Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
28 participants
INTERVENTIONAL
2013-10-31
2014-10-31
Brief Summary
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Detailed Description
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The two product pigmentation reducing herbal regimen is based on the novel concept of inhibiting all 14 major and the 3 branch steps in the melanin cascade.
Conditions
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Study Design
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NON_RANDOMIZED
SINGLE_GROUP
TREATMENT
QUADRUPLE
Study Groups
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4% Hydroquinone
4% hydroquinone applied to one side of the face.
Hydroquinone
Hydroquinone 4% is applied twice a day to either the left or right side of the face for a duration of 4 months.
Herbal depigmenting agent
Herbal depigmenting agent applied on the other side of the face.
Herbal depigmenting agent (Epionce)
A two product herbal pigmentation reducing regimen is applied twice a day to either the left or right side of the face for a duration of 4 months.
Interventions
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Herbal depigmenting agent (Epionce)
A two product herbal pigmentation reducing regimen is applied twice a day to either the left or right side of the face for a duration of 4 months.
Hydroquinone
Hydroquinone 4% is applied twice a day to either the left or right side of the face for a duration of 4 months.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Must be in good general health
* Must be willing to use sunscreen on the face daily
* Must be willing to avoid tanning beds and excessive exposure to direct sunlight
* Must be willing to continue using regular cosmetic regimen
Exclusion Criteria
* Using a medication that increases sensitivity to sunlight including doxycycline, minocycline, tetracycline, ciprofloxin, hydrochlorothiazide, and sulfonamides.
* Any known allergies/sensitivities to facial skincare products, anti-aging products, de-pigmenting products, or products containing hydroquinone
* Usage of any new skincare products during the course of the study
* Presence of atopic dermatitis or psoriasis on the face
* Uncontrolled diabetes, hypertension, hypothyroidism, hyperthyroidism
* TCA or other deep peels within 1 year or medium to light peels within 3 months prior to starting the study
* Facial/laser treatment within the last 3 months
* Facial cosmetic surgery within the last 12 months
* Use of product, topical, or systemic medication, known to affect dyschromia, having "whitening" or anti-aging properties
* Physical skin conditions such as excessive hair, scarring, tattoos that might impair evaluations of the test sites
* Active hepatitis, immune deficiency, or autoimmune disease
30 Years
65 Years
FEMALE
Yes
Sponsors
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Episciences, Inc.
INDUSTRY
Sadick Research Group
OTHER
Responsible Party
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Principal Investigators
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Neil S Sadick, MD
Role: PRINCIPAL_INVESTIGATOR
Sadick Research Group
Locations
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Sadick Research Group
New York, New York, United States
Countries
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Other Identifiers
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SRG-EPI-1
Identifier Type: -
Identifier Source: org_study_id