Investigation of the Proportion of Human Epidermal Growth Factor Receptor 2 Protein Overexpression of Gastric Adenocarcinoma and Prognostic Effect of HER2, and Analysis of Practice Pattern of Herceptin Use in Stage IV Gastric Cancer

NCT ID: NCT02136836

Last Updated: 2014-05-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

860 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-05-31

Brief Summary

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The objective of this study is to investigate the proportion of HER2 overexpression in gastric cancer patients group, to evaluate the relation of HER2 overexpression with prognosis, and to analyze the proportion of herceptin applied to patients in clinical field. Furthermore, the investigators are going to reevaluate the clinical benefit of Herceptin for survival prolongation compared to chemotherapy only.

Detailed Description

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Conditions

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Stomach Neoplasms

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Study Groups

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gastric adenocarcinoma

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. Histologically confirmed gastric adenocarcinoma
2. Patients were diagnosed during 2006-2013
3. HER2 expression status was evaluated in primary gastric cancer or metastatic lesion.

Exclusion Criteria

* Patients with second primary cancer within 5 years
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Yonsei University

OTHER

Sponsor Role lead

Responsible Party

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Jae Yong Cho

Chief of division of medical oncology, Gangnam Severance Hospital

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jae Yong Cho, M.D.,Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Gangnam Severance Hospital, Yonsei University

Locations

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Gangnam Severance Hospital

Seoul, , South Korea

Site Status

Countries

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South Korea

Other Identifiers

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Roche

Identifier Type: OTHER

Identifier Source: secondary_id

GSCH-STO13-01

Identifier Type: -

Identifier Source: org_study_id

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