My Mobile Advice Program: A Randomized Pilot Feasibility Study

NCT ID: NCT02136498

Last Updated: 2017-11-13

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

66 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-10-31

Study Completion Date

2016-02-29

Brief Summary

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The purpose of this pilot study is to evaluate the acceptability and feasibility of the proposed smoking cessation intervention (called MyMAP or My Mobile Advice Program).

Detailed Description

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Investigators will develop and pilot test a prototype of the MyMAP intervention.The intervention is designed to help smokers better manage issues known to reduce treatment adherence (withdrawal symptoms, medication side-effects, low motivation, and inadequate behavioral skills for medication adherence) and to facilitate greater communication between patients and providers so clinicians can provide appropriate oversight of medication use, intervene when medically necessary, and address patient concerns that may otherwise lead to non-adherence or early treatment termination.

Conditions

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Smoking Cessation Medication Adherence

Keywords

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smoking cessation varenicline adherence

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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mHealth self-help + varenicline

Participants in this control arm received standard cognitive-behavioral self-help materials delivered via a mobile health (mHealth) program + a standard course of varenicline.

Group Type ACTIVE_COMPARATOR

Varenicline

Intervention Type DRUG

Standard 12 week course of varenicline, provided in both arms

Cognitive-behavioral self-help

Intervention Type BEHAVIORAL

Standard self-help education for smoking cessation, delivered via mobile-optimized website accessible via smartphone.

mHealth MyMAP program + varenicline

Participants in the experimental arm received standard cognitive-behavioral self-help materials delivered via a mHealth program + additional personalized support features (automated, tailored advice managing nicotine withdrawal symptoms and medication side-effects \& secure messaging with a cessation counselor; i.e., MyMAP program) + a standard course of varenicline.

Group Type EXPERIMENTAL

Varenicline

Intervention Type DRUG

Standard 12 week course of varenicline, provided in both arms

Cognitive-behavioral self-help

Intervention Type BEHAVIORAL

Standard self-help education for smoking cessation, delivered via mobile-optimized website accessible via smartphone.

MyMAP (My Mobile Advice Program)

Intervention Type BEHAVIORAL

Same standard self-help intervention as in control arm + automatically-tailored support and advice for managing nicotine withdrawal symptoms + secure messaging with cessation counselor

Interventions

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Varenicline

Standard 12 week course of varenicline, provided in both arms

Intervention Type DRUG

Cognitive-behavioral self-help

Standard self-help education for smoking cessation, delivered via mobile-optimized website accessible via smartphone.

Intervention Type BEHAVIORAL

MyMAP (My Mobile Advice Program)

Same standard self-help intervention as in control arm + automatically-tailored support and advice for managing nicotine withdrawal symptoms + secure messaging with cessation counselor

Intervention Type BEHAVIORAL

Other Intervention Names

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Chantix

Eligibility Criteria

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Inclusion Criteria

* An invited member of Group Health, a health care system in the Pacific Northwest
* Plan to remain enrolled in Group Health for the next 6 months
* aged 18 - 65
* Eligible for smoking cessation treatment through Group Health insurance coverage
* smoke \>= 10 cigs a day
* speak and read in English
* willing to use varenicline and no contraindications for this medication
* ready to quit smoking
* have a smart phone with internet access
* willing to receive study texts and emails
* receive care at a Group Health clinic and have electronic medical records in this system
* fill prescriptions through the Group Health pharmacy
* agree to use birth control while taking study medication, if there is a risk of pregnancy

Exclusion Criteria

* lifetime history of dementia
* psychosis or bipolar disorder based on self-report or medical record review
* hearing, comprehension or visual limitations that preclude full study participation
* current use of other forms of tobacco
* any medical contraindication for varenicline use
* documented history of suicidal ideation/intent
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Michigan

OTHER

Sponsor Role collaborator

University of California, Davis

OTHER

Sponsor Role collaborator

Kaiser Permanente

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jennifer McClure, PhD

Role: PRINCIPAL_INVESTIGATOR

Group Health Research Institute

Sheryl Catz, PhD

Role: PRINCIPAL_INVESTIGATOR

University of California, Davis

Larry An, MD

Role: PRINCIPAL_INVESTIGATOR

University of Michigan

Locations

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Group Health Research Institute

Seattle, Washington, United States

Site Status

Countries

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United States

References

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McClure JB, Anderson ML, Bradley K, An LC, Catz SL. Evaluating an Adaptive and Interactive mHealth Smoking Cessation and Medication Adherence Program: A Randomized Pilot Feasibility Study. JMIR Mhealth Uhealth. 2016 Aug 3;4(3):e94. doi: 10.2196/mhealth.6002.

Reference Type RESULT
PMID: 27489247 (View on PubMed)

Related Links

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Other Identifiers

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1R34DA034612

Identifier Type: NIH

Identifier Source: org_study_id

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