Influence of Bionecteurs on Catheter-associated Infection

NCT ID: NCT02134769

Last Updated: 2016-11-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

221 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-08-31

Study Completion Date

2015-12-31

Brief Summary

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Bionecteur® is a protective non-touch applicator to ensure aseptic connection made by Vygon. However, there are no studies describing a positive effect of using Bionecteurs ® in regard to catheter-related bloodstream infections. In this study Bionecteur® will be used on central venous lines and arterial lines in postoperative patients of a 40-bed ICU. The incidence of catheter-related bloodstream infections will we compared to patients without inclusion of Bionecteur® devices.

Detailed Description

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* Prospective, randomised observational study
* Postsurgical patients in an anesthesiological ICU with ICU LOS (LOS: length of stay) \> 3 days

* Inclusion:

\---- Age ≥ 18 years

---. demand of central venous and arterial line

\--- written consent of patient and/or assignee
* Exclusion

* Handicapped patients
* patient with ICU LOS \< 3 days
* Study design

1. Three days after admission to ICU blood cultures are drawn to exclude preexisting blood stream infection
2. Patients in a bed with even number are assigned to Bionecteur® group. Control group (without using bionecteurs) are patients with an odd bed number.
3. Biconecteurs® are connected to all lumens of the central catheter and to arterial catheter. Control group is treated without using Bionecteurs®. Handling of vascular catheters are performed as described in institutional guidelines in both groups.
4. Catheter-related bloodstream infections are monitored by an independent person during ICU treatment
5. The study will be finished ab discharge of ICU or removal of catheters.

Conditions

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Infection

Keywords

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catheter-related bloodstream infections

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Participants

Study Groups

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Control

No use of Bionecteur; handling according to institutional guideline

Group Type NO_INTERVENTION

No interventions assigned to this group

Bionecteur

Use of Bionecteur; handling according to institutional guideline

Group Type ACTIVE_COMPARATOR

Bionecteur

Intervention Type DEVICE

Using Bionecteur at each lumina of the catheter; handling according to institutional guideline

Interventions

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Bionecteur

Using Bionecteur at each lumina of the catheter; handling according to institutional guideline

Intervention Type DEVICE

Other Intervention Names

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bionector® company: Vygon

Eligibility Criteria

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Inclusion Criteria

* Length of Stay (LOS) in ICU \> 3 days
* written consent by patient or notarial carers
* medical indication for central venous line/arterial line

Exclusion Criteria

* handicap
* LOS ICU \< 3 days
* no consent
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Vygon GmbH & Co. KG

INDUSTRY

Sponsor Role collaborator

University Hospital Tuebingen

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Helene A Haeberle, MD

Role: PRINCIPAL_INVESTIGATOR

University Hospital Tuebingen, Germany

Locations

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University Hospital Tuebingen

Tübingen, , Germany

Site Status

Countries

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Germany

References

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Koeppen M, Weinert F, Oehlschlaeger S, Koerner A, Rosenberger P, Haeberle HA. Needle-free connectors catheter-related bloodstream infections: a prospective randomized controlled trial. Intensive Care Med Exp. 2019 Dec 2;7(1):63. doi: 10.1186/s40635-019-0277-7.

Reference Type DERIVED
PMID: 31792889 (View on PubMed)

Other Identifiers

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ZVK-Bionect

Identifier Type: OTHER

Identifier Source: secondary_id

BIONECT-2014

Identifier Type: -

Identifier Source: org_study_id