Trial Outcomes & Findings for Shared Health Appointments and Reciprocal Enhanced Support (NCT NCT02132676)

NCT ID: NCT02132676

Last Updated: 2020-09-02

Results Overview

Glycemic control (measured by Hemoglobin A1c) in each group will be assessed by the comparison of an average of the values obtained during routine outpatient clinical practice in 6-month windows preceding baseline and following the 6 and 12-month post-enrollment evaluation periods. In addition to measuring absolute values of A1c, the investigators will also examine the change in the percentage of patients with an average A1c \> 8%.

Recruitment status

COMPLETED

Target enrollment

1536 participants

Primary outcome timeframe

6 months and 12 months post-enrollment

Results posted on

2020-09-02

Participant Flow

Participant milestones

Participant milestones
Measure
Usual Care
Randomly selected sample of those not offered participation in a Shared Medical Appointment (SMA)
Active Treatment
All those scheduled for a Shared Medical Appointment (SMA), regardless of whether an SMA was actually attended
Overall Study
STARTED
727
809
Overall Study
COMPLETED
727
809
Overall Study
NOT COMPLETED
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Shared Health Appointments and Reciprocal Enhanced Support

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Usual Care
n=727 Participants
Randomly selected sample of those not offered participation in a Shared Medical Appointment (SMA)
Active Treatment
n=809 Participants
All those scheduled for a Shared Medical Appointment (SMA), regardless of whether an SMA was actually attended
Total
n=1536 Participants
Total of all reporting groups
Age, Continuous
67.8 years
STANDARD_DEVIATION 12.7 • n=5 Participants
67.1 years
STANDARD_DEVIATION 9.2 • n=7 Participants
67.5 years
STANDARD_DEVIATION 11.0 • n=5 Participants
Sex: Female, Male
Female
20 Participants
n=5 Participants
27 Participants
n=7 Participants
47 Participants
n=5 Participants
Sex: Female, Male
Male
707 Participants
n=5 Participants
782 Participants
n=7 Participants
1489 Participants
n=5 Participants
Race (NIH/OMB)
American Indian or Alaska Native
6 Participants
n=5 Participants
7 Participants
n=7 Participants
13 Participants
n=5 Participants
Race (NIH/OMB)
Asian
23 Participants
n=5 Participants
27 Participants
n=7 Participants
50 Participants
n=5 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
9 Participants
n=5 Participants
14 Participants
n=7 Participants
23 Participants
n=5 Participants
Race (NIH/OMB)
Black or African American
85 Participants
n=5 Participants
148 Participants
n=7 Participants
233 Participants
n=5 Participants
Race (NIH/OMB)
White
536 Participants
n=5 Participants
545 Participants
n=7 Participants
1081 Participants
n=5 Participants
Race (NIH/OMB)
More than one race
7 Participants
n=5 Participants
8 Participants
n=7 Participants
15 Participants
n=5 Participants
Race (NIH/OMB)
Unknown or Not Reported
61 Participants
n=5 Participants
60 Participants
n=7 Participants
121 Participants
n=5 Participants
A1c
8.9 percent
STANDARD_DEVIATION 1.3 • n=5 Participants
9.1 percent
STANDARD_DEVIATION 1.5 • n=7 Participants
9.0 percent
STANDARD_DEVIATION 1.4 • n=5 Participants
SBP
137.7 mmHg
STANDARD_DEVIATION 15.2 • n=5 Participants
136.2 mmHg
STANDARD_DEVIATION 13.4 • n=7 Participants
136.8 mmHg
STANDARD_DEVIATION 14.2 • n=5 Participants
On insulin
255 Participants
n=5 Participants
385 Participants
n=7 Participants
640 Participants
n=5 Participants
On statin
470 Participants
n=5 Participants
603 Participants
n=7 Participants
1073 Participants
n=5 Participants
Classes of anti-hypertensive meds
2.2 number of classes of antihypertensives
STANDARD_DEVIATION 1.3 • n=5 Participants
2.4 number of classes of antihypertensives
STANDARD_DEVIATION 1.2 • n=7 Participants
2.3 number of classes of antihypertensives
STANDARD_DEVIATION 1.2 • n=5 Participants
Primary Care Physician (PCP) in-person visits in past 8 months
3.2 number of in-person PCP visits
STANDARD_DEVIATION 3.4 • n=5 Participants
3.4 number of in-person PCP visits
STANDARD_DEVIATION 3.1 • n=7 Participants
3.3 number of in-person PCP visits
STANDARD_DEVIATION 3.3 • n=5 Participants
PCP phone visits in past 8 months
0.7 number of PCP phone visits
STANDARD_DEVIATION 1.5 • n=5 Participants
0.7 number of PCP phone visits
STANDARD_DEVIATION 1.2 • n=7 Participants
0.7 number of PCP phone visits
STANDARD_DEVIATION 1.3 • n=5 Participants
Nurse case manager in-person visits in past 8 months
0.2 number of RNCM in-person visits
STANDARD_DEVIATION 0.8 • n=5 Participants
0.2 number of RNCM in-person visits
STANDARD_DEVIATION 0.7 • n=7 Participants
0.2 number of RNCM in-person visits
STANDARD_DEVIATION 0.7 • n=5 Participants
Nurse case manager phone visits in past 8 months
0.3 number of RNCM phone visits
STANDARD_DEVIATION 0.9 • n=5 Participants
0.3 number of RNCM phone visits
STANDARD_DEVIATION 0.9 • n=7 Participants
0.3 number of RNCM phone visits
STANDARD_DEVIATION 0.9 • n=5 Participants
Endocrinology in-person visits in past 8 months
0.2 number of Endocrinology in-person visits
STANDARD_DEVIATION 0.8 • n=5 Participants
0.3 number of Endocrinology in-person visits
STANDARD_DEVIATION 0.8 • n=7 Participants
0.3 number of Endocrinology in-person visits
STANDARD_DEVIATION 0.8 • n=5 Participants

PRIMARY outcome

Timeframe: 6 months and 12 months post-enrollment

Population: Only those with A1c values documented in the electronic health record (EHR) during the evaluation windows were included in the number analyzed

Glycemic control (measured by Hemoglobin A1c) in each group will be assessed by the comparison of an average of the values obtained during routine outpatient clinical practice in 6-month windows preceding baseline and following the 6 and 12-month post-enrollment evaluation periods. In addition to measuring absolute values of A1c, the investigators will also examine the change in the percentage of patients with an average A1c \> 8%.

Outcome measures

Outcome measures
Measure
Usual Care
n=727 Participants
Randomly selected sample of those not offered participation in a Shared Medical Appointment (SMA)
Active Treatment
n=809 Participants
All those scheduled for a Shared Medical Appointment (SMA), regardless of whether an SMA was actually attended
Change in Glycemic Control
Baseline
8.92 % glycolated hemoglobin
Standard Deviation 1.31
9.12 % glycolated hemoglobin
Standard Deviation 1.48
Change in Glycemic Control
6-Months
8.26 % glycolated hemoglobin
Standard Deviation 1.47
8.16 % glycolated hemoglobin
Standard Deviation 1.37
Change in Glycemic Control
12-Months
8.15 % glycolated hemoglobin
Standard Deviation 1.50
8.15 % glycolated hemoglobin
Standard Deviation 1.40

SECONDARY outcome

Timeframe: 6 months and 12 months post-enrollment

Population: Only those with SBP values documented in the EHR during the evaluation windows were included in the number analyzed

Systolic blood pressure (SBP) in each group will be assessed by the comparison of an average of the values obtained during routine outpatient clinical practice in 6-month windows preceding baseline and following the 6 and 12-month post-enrollment evaluation periods. In addition to measuring absolute values, the investigators will also examine the change in percentage of patients with an average SBP \> 140.

Outcome measures

Outcome measures
Measure
Usual Care
n=727 Participants
Randomly selected sample of those not offered participation in a Shared Medical Appointment (SMA)
Active Treatment
n=809 Participants
All those scheduled for a Shared Medical Appointment (SMA), regardless of whether an SMA was actually attended
Change in Systolic Blood Pressure (SBP)
Baseline
139.6 mmHg
Standard Deviation 18.9
137.2 mmHg
Standard Deviation 17.5
Change in Systolic Blood Pressure (SBP)
6-Moths
139.6 mmHg
Standard Deviation 20.5
136.2 mmHg
Standard Deviation 18.7
Change in Systolic Blood Pressure (SBP)
12-Months
139.3 mmHg
Standard Deviation 19.7
137.4 mmHg
Standard Deviation 19.5

SECONDARY outcome

Timeframe: 6 months and 12 months post-enrollment

The number of participants who are not on insulin at baseline and are started on insulin during the 6 and 12-month post-enrollment periods will be totaled and compared for the SMA group and the no intervention control group. For the no intervention control group, baseline will be the date they are identified by the data manager. For the SMA group, baseline will be the date of the first SMA.

Outcome measures

Outcome measures
Measure
Usual Care
n=727 Participants
Randomly selected sample of those not offered participation in a Shared Medical Appointment (SMA)
Active Treatment
n=809 Participants
All those scheduled for a Shared Medical Appointment (SMA), regardless of whether an SMA was actually attended
Insulin Starts
Baseline
255 Participants
385 Participants
Insulin Starts
6-Months
247 Participants
418 Participants
Insulin Starts
12-Months
246 Participants
406 Participants

SECONDARY outcome

Timeframe: 6 months and 12 months post-enrollment

Major utilization events (admissions, bed days of care, and outpatient visits) will be collected from electronic medical records. Outpatient visits will be limited to those clinics most likely to be impacted by the intervention (e.g., primary care visits, diabetes specialty visits, and nurse visits).

Outcome measures

Outcome measures
Measure
Usual Care
n=727 Participants
Randomly selected sample of those not offered participation in a Shared Medical Appointment (SMA)
Active Treatment
n=809 Participants
All those scheduled for a Shared Medical Appointment (SMA), regardless of whether an SMA was actually attended
Emergency Department (ED) Visits
12-Months
0.50 number of ED visits
Standard Deviation 1.26
0.60 number of ED visits
Standard Deviation 1.31
Emergency Department (ED) Visits
Baseline
0.51 number of ED visits
Standard Deviation 1.24
0.54 number of ED visits
Standard Deviation 1.16
Emergency Department (ED) Visits
6-Months
0.42 number of ED visits
Standard Deviation 1.04
0.68 number of ED visits
Standard Deviation 1.36

SECONDARY outcome

Timeframe: 6 months and 12 months post-enrollment

The number of participants who are not on a statin at baseline and are started on insulin during the 6 and 12-month post-enrollment periods will be totaled and compared for the SMA group and the no intervention control group. For the no intervention control group, baseline will be the date they are identified by the data manager. For the SMA group, baseline will be the date of the first SMA.

Outcome measures

Outcome measures
Measure
Usual Care
n=727 Participants
Randomly selected sample of those not offered participation in a Shared Medical Appointment (SMA)
Active Treatment
n=809 Participants
All those scheduled for a Shared Medical Appointment (SMA), regardless of whether an SMA was actually attended
Statin Starts
Baseline
470 Participants
603 Participants
Statin Starts
6-Months
456 Participants
617 Participants
Statin Starts
12-Months
446 Participants
608 Participants

SECONDARY outcome

Timeframe: 6 months and 12 months post-enrollment

Population: Only those participants who were on at least one anti-hypertensive med during the evaluation windows were included in the number analyzed

Change in antihypertensive use (number of classes of prescribed anti-hypertensives) in each group will be assessed at baseline and following the 6 and 12-month post-enrollment evaluation periods. For the no intervention control group, baseline will be the date they are identified by the data manager. For the SMA group, baseline will be the date of the first SMA.

Outcome measures

Outcome measures
Measure
Usual Care
n=727 Participants
Randomly selected sample of those not offered participation in a Shared Medical Appointment (SMA)
Active Treatment
n=809 Participants
All those scheduled for a Shared Medical Appointment (SMA), regardless of whether an SMA was actually attended
Change in Number of Classes of Anti-hypertensive Meds
Baseline
2.23 Number of classes of anti-hypertensives
Standard Deviation 1.27
2.38 Number of classes of anti-hypertensives
Standard Deviation 1.21
Change in Number of Classes of Anti-hypertensive Meds
6-Months
2.31 Number of classes of anti-hypertensives
Standard Deviation 1.28
2.38 Number of classes of anti-hypertensives
Standard Deviation 1.19
Change in Number of Classes of Anti-hypertensive Meds
12-Months
2.28 Number of classes of anti-hypertensives
Standard Deviation 1.19
2.39 Number of classes of anti-hypertensives
Standard Deviation 1.24

SECONDARY outcome

Timeframe: 6 months and 12 months post-enrollment

Population: Only those who completed each timepoint's survey and responded to the relevant scale items were included in the number analyzed

Patients' satisfaction with VA care will be assessed through surveys at baseline and 6 and 12 months post-enrollment for the SMA group. The following relates to the scale used: Scale name: VA Healthcare Satisfaction Scale Scale ranges: 1-6 (Strongly Disagree=1, Disagree=2, Slightly Disagree=3, Slightly Agree=4, Agree=5, Strongly Agree=6) Direction of range: Higher score indicates a better outcome

Outcome measures

Outcome measures
Measure
Usual Care
n=448 Participants
Randomly selected sample of those not offered participation in a Shared Medical Appointment (SMA)
Active Treatment
All those scheduled for a Shared Medical Appointment (SMA), regardless of whether an SMA was actually attended
Change in Patient-reported Satisfaction With VA Care
Baseline
4.58 units on a scale
Standard Deviation 1.04
Change in Patient-reported Satisfaction With VA Care
6-Months
4.97 units on a scale
Standard Deviation 0.98
Change in Patient-reported Satisfaction With VA Care
12-Months
4.88 units on a scale
Standard Deviation 1.08

SECONDARY outcome

Timeframe: 6 months and 12 months post-enrollment

Population: Only those who completed each timepoint's survey and responded to the relevant scale items were included in the number analyzed

Patients' level of diabetes distress will be assessed through surveys at baseline and 6 and 12 months post-enrollment for the SMA group. The following relates to the scale used: Scale name: Diabetes Distress Scale Scale ranges: 1-5 (Not a Problem=1, Minor Problem=2, Moderate Problem=3, Somewhat Serious Problem=4, Serious Problem=5) Direction of range: Lower score indicates a better outcome

Outcome measures

Outcome measures
Measure
Usual Care
n=451 Participants
Randomly selected sample of those not offered participation in a Shared Medical Appointment (SMA)
Active Treatment
All those scheduled for a Shared Medical Appointment (SMA), regardless of whether an SMA was actually attended
Change in Patient-reported Diabetes Distress
Baseline
2.43 units on a scale
Standard Deviation 1.02
Change in Patient-reported Diabetes Distress
6-Months
2.19 units on a scale
Standard Deviation 0.99
Change in Patient-reported Diabetes Distress
12-Months
2.03 units on a scale
Standard Deviation 0.93

SECONDARY outcome

Timeframe: 6 months and 12 months post-enrollment

Population: Only those who completed each timepoint's survey and responded to the relevant scale items were included in the number analyzed

Patients' degree of diabetes support will be assessed through surveys at baseline and 6 and 12 months post-enrollment for the SMA group. The following relates to the scale used: Scale name: Diabetes Support Scale Scale ranges: 1-6 (Strongly Disagree=1, Disagree=2, Slightly Disagree=3, Slightly Agree=4, Agree=5, Strongly Agree=6) Direction of range: Higher score indicates a better outcome

Outcome measures

Outcome measures
Measure
Usual Care
n=446 Participants
Randomly selected sample of those not offered participation in a Shared Medical Appointment (SMA)
Active Treatment
All those scheduled for a Shared Medical Appointment (SMA), regardless of whether an SMA was actually attended
Change in Patient-reported Degree of Diabetes Support
Baseline
3.77 units on a scale
Standard Deviation 1.30
Change in Patient-reported Degree of Diabetes Support
6-Months
4.29 units on a scale
Standard Deviation 1.25
Change in Patient-reported Degree of Diabetes Support
12-Months
4.09 units on a scale
Standard Deviation 1.37

SECONDARY outcome

Timeframe: 6 months and 12 months post-enrollment

Population: Only those who completed each timepoint's survey and responded to the relevant scale items were included in the number analyzed

Patients' degree of self-efficacy will be assessed through surveys at baseline and 6 and 12 months post-enrollment for the SMA group. The following relates to the scale used: Scale name: Williams Self-Efficacy Scale Scale ranges: 1-6 (Strongly Disagree=1, Disagree=2, Slightly Disagree=3, Slightly Agree=4, Agree=5, Strongly Agree=6) Direction of range: Higher score indicates a better outcome

Outcome measures

Outcome measures
Measure
Usual Care
n=449 Participants
Randomly selected sample of those not offered participation in a Shared Medical Appointment (SMA)
Active Treatment
All those scheduled for a Shared Medical Appointment (SMA), regardless of whether an SMA was actually attended
Change in Patient-reported Degree of Self-Efficacy
Baseline
4.51 units on a scale
Standard Deviation 1.05
Change in Patient-reported Degree of Self-Efficacy
6-Months
4.84 units on a scale
Standard Deviation 1.02
Change in Patient-reported Degree of Self-Efficacy
12-Months
4.87 units on a scale
Standard Deviation 1.05

SECONDARY outcome

Timeframe: 6 months and 12 months post-enrollment

Major utilization events (admissions, bed days of care, and outpatient visits) will be collected from electronic medical records. Outpatient visits will be limited to those clinics most likely to be impacted by the intervention (e.g., primary care visits, diabetes specialty visits, and nurse visits).

Outcome measures

Outcome measures
Measure
Usual Care
n=727 Participants
Randomly selected sample of those not offered participation in a Shared Medical Appointment (SMA)
Active Treatment
n=809 Participants
All those scheduled for a Shared Medical Appointment (SMA), regardless of whether an SMA was actually attended
Hospitalizations
Baseline
0.12 number of hospitalizations
Standard Deviation 0.46
0.10 number of hospitalizations
Standard Deviation 0.36
Hospitalizations
6-Months
0.12 number of hospitalizations
Standard Deviation 0.52
0.15 number of hospitalizations
Standard Deviation 0.56
Hospitalizations
12-Months
0.14 number of hospitalizations
Standard Deviation 0.55
0.12 number of hospitalizations
Standard Deviation 0.52

SECONDARY outcome

Timeframe: 6 months and 12 months post-enrollment

Population: Only those participants who had at least one hospitalization during the evaluation windows were included in the number analyzed

Major utilization events (admissions, bed days of care, and outpatient visits) will be collected from electronic medical records. Outpatient visits will be limited to those clinics most likely to be impacted by the intervention (e.g., primary care visits, diabetes specialty visits, and nurse visits).

Outcome measures

Outcome measures
Measure
Usual Care
n=727 Participants
Randomly selected sample of those not offered participation in a Shared Medical Appointment (SMA)
Active Treatment
n=810 Participants
All those scheduled for a Shared Medical Appointment (SMA), regardless of whether an SMA was actually attended
Length of Hospitalizations
Baseline
6.1 days
Standard Deviation 12.7
3.1 days
Standard Deviation 3.2
Length of Hospitalizations
6-Months
12.7 days
Standard Deviation 33.2
6.3 days
Standard Deviation 9.3
Length of Hospitalizations
12-Months
7.3 days
Standard Deviation 9.2
8.6 days
Standard Deviation 21.5

SECONDARY outcome

Timeframe: 6 months and 12 months post-enrollment

Major utilization events (admissions, bed days of care, and outpatient visits) will be collected from electronic medical records. Outpatient visits will be limited to those clinics most likely to be impacted by the intervention (e.g., primary care visits, diabetes specialty visits, and nurse visits).

Outcome measures

Outcome measures
Measure
Usual Care
n=727 Participants
Randomly selected sample of those not offered participation in a Shared Medical Appointment (SMA)
Active Treatment
n=809 Participants
All those scheduled for a Shared Medical Appointment (SMA), regardless of whether an SMA was actually attended
PCP Visits
Baseline
1.65 number of PCP visits
Standard Deviation 1.47
1.57 number of PCP visits
Standard Deviation 1.30
PCP Visits
6-Months
1.04 number of PCP visits
Standard Deviation 1.20
1.42 number of PCP visits
Standard Deviation 1.37
PCP Visits
12-Months
1.11 number of PCP visits
Standard Deviation 1.19
1.38 number of PCP visits
Standard Deviation 1.29

SECONDARY outcome

Timeframe: 6 months and 12 months post-enrollment

Major utilization events (admissions, bed days of care, and outpatient visits) will be collected from electronic medical records. Outpatient visits will be limited to those clinics most likely to be impacted by the intervention (e.g., primary care visits, diabetes specialty visits, and nurse visits).

Outcome measures

Outcome measures
Measure
Usual Care
n=727 Participants
Randomly selected sample of those not offered participation in a Shared Medical Appointment (SMA)
Active Treatment
n=809 Participants
All those scheduled for a Shared Medical Appointment (SMA), regardless of whether an SMA was actually attended
Nurse Case Manager Visits
Baseline
0.40 number of RNCM visits
Standard Deviation 1.12
0.42 number of RNCM visits
Standard Deviation 1.09
Nurse Case Manager Visits
6-Months
0.08 number of RNCM visits
Standard Deviation 0.38
0.29 number of RNCM visits
Standard Deviation 0.86
Nurse Case Manager Visits
12-Months
0.18 number of RNCM visits
Standard Deviation 0.74
0.23 number of RNCM visits
Standard Deviation 0.78

SECONDARY outcome

Timeframe: 6 months and 12 months post-enrollment

Major utilization events (admissions, bed days of care, and outpatient visits) will be collected from electronic medical records. Outpatient visits will be limited to those clinics most likely to be impacted by the intervention (e.g., primary care visits, diabetes specialty visits, and nurse visits).

Outcome measures

Outcome measures
Measure
Usual Care
n=727 Participants
Randomly selected sample of those not offered participation in a Shared Medical Appointment (SMA)
Active Treatment
n=809 Participants
All those scheduled for a Shared Medical Appointment (SMA), regardless of whether an SMA was actually attended
Endocrinology Visits
Baseline
0.18 number of Endocrinology visits
Standard Deviation 0.69
0.21 number of Endocrinology visits
Standard Deviation 0.64
Endocrinology Visits
6-Months
0.15 number of Endocrinology visits
Standard Deviation 0.68
0.20 number of Endocrinology visits
Standard Deviation 0.61
Endocrinology Visits
12-Months
0.15 number of Endocrinology visits
Standard Deviation 0.62
0.21 number of Endocrinology visits
Standard Deviation 0.63

Adverse Events

Usual Care

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Active Treatment

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Michele Heisler

VA Ann Arbor Healthcare System Center for Clinical Management & Research

Phone: 734-845-3502

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place