The Purpose of the Study is to Examine Whether Iron Deficiency Anemia is Associated With Increased Production of Thrombin and Whether Correction of Anemia by Providing Iron Intravenously Causes a Significant Reduction in Production of Thrombin.

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

82 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-10-31

Study Completion Date

2015-12-31

Brief Summary

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In total 50 subjects with iron deficiency anemia treated with intravenous iron are planned for inclusion in this trial. After signing an informed consent a blood sample will be obtained from each participant before iron treatment. The investigators will measure the thrombin generation in plasma assessed by the calibrated automated thrombogram (CAT). patient will go face to face interview and will be asked to answer structured questionnaire which will include information on demographics, clinical data ( fever, allergies , etc.) and comorbidities

Two weeks after completing intravenous iron administration additional blood samples will be taken: thrombin generation will be measured

Detailed Description

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Conditions

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Iron Deficiency Anemias

Keywords

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Anemias Iron-Deficiency thrombin

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* age \>18 years
* Iron deficiency anemia that did not response to oral iron treatment and is planned to receive iron supplement intravenously.
* Signing the informed consent

Exclusion Criteria

* chronic inflammatory disease
* renal failure
* Malignancy
* Infectious disease
* Other reason for anemia except iron deficiency anemia.
* Pregnant women
* Use of anti aggregating agents or anticoagulants

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Elias mazen

prof mazen elias

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Haemek medical center

Afula, , Israel

Site Status

Countries

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Israel

Other Identifiers

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thrombingeneration- anemia

Identifier Type: -

Identifier Source: org_study_id