The Effectiveness of AAD and IPV to Treat Hospitalized Infants (<2years) With Acute Viral Bronchiolitis.

NCT ID: NCT02126748

Last Updated: 2015-03-11

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

103 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-12-31

Study Completion Date

2015-01-31

Brief Summary

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The purpose of this study is to investigate the effectiveness of two airway clearance techniques; Intrapulmonary Percussive Ventilation and Assisted Autogenic Drainage in hospitalized infants under the age of 2 with acute viral bronchiolitis.

Detailed Description

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Conditions

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Bronchiolitis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Intrapulmonary Percussive Ventilation

20 min of IPV administered to the patient inhalation 4ml hypertonic saline 3% 3x/day

Group Type EXPERIMENTAL

inhalation 4ml hypertonic saline 3% 3x/day

Intervention Type OTHER

Intrapulmonary Percussive Ventilation

Intervention Type DEVICE

Assisted Autogenic Drainage

20 min of AAD administered to the patient inhalation 4ml hypertonic saline 3% 3x/day

Group Type ACTIVE_COMPARATOR

inhalation 4ml hypertonic saline 3% 3x/day

Intervention Type OTHER

Assisted Autogenic Drainage

Intervention Type PROCEDURE

control

20 min of bouncing administered tot the patient inhalation 4ml hypertonic saline 3% 3x/day

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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inhalation 4ml hypertonic saline 3% 3x/day

Intervention Type OTHER

Intrapulmonary Percussive Ventilation

Intervention Type DEVICE

Assisted Autogenic Drainage

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* first period of wheezing
* Wang score between 3 and 7
* age \< 24 months
* Sa02\> 90%

Exclusion Criteria

* ICU patients
* mechanical ventilation
* use of antibiotics
* use of corticosteroids
* gestational age \< 34 weeks
* chronic cardiac or pulmonary disease
* no parental consent
Minimum Eligible Age

1 Day

Maximum Eligible Age

24 Months

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Vrije Universiteit Brussel

OTHER

Sponsor Role lead

Responsible Party

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Filip Van Ginderdeuren

PT,Drs

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Uz Brussel

Jette, Brussels Capital, Belgium

Site Status

Countries

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Belgium

References

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Roque-Figuls M, Gine-Garriga M, Granados Rugeles C, Perrotta C, Vilaro J. Chest physiotherapy for acute bronchiolitis in paediatric patients between 0 and 24 months old. Cochrane Database Syst Rev. 2023 Apr 3;4(4):CD004873. doi: 10.1002/14651858.CD004873.pub6.

Reference Type DERIVED
PMID: 37010196 (View on PubMed)

Other Identifiers

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FVG003

Identifier Type: -

Identifier Source: org_study_id

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