National Registry for Egyptian Pediatric Neuromuscular Diseases

NCT ID: NCT02124616

Last Updated: 2014-04-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-04-30

Study Completion Date

2020-12-31

Brief Summary

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Our aim is to establish multi-center national Egyptian database of information for inherited and acquired neuromuscular diseases in infants and children from 0 to 18 years of age.

Detailed Description

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Aims: An open-ended multi-center, national Egyptian study to collect and analyze data for children with Neuromuscular Diseases (NMD) inherited NMD (spinal muscular atrophy (SMA), Duchenne/Becker and congenital muscular dystrophies (DMD/BMD, CMD), congenital myopathies, and congenital myasthenic syndromes) and acquired NMD (neuropathies, myasthenia gravis and myositis).

Participants: Eligible infants and children with inherited and acquired neuromuscular diseases.

DESIGN: This study is a prospective cohort study.

Outcome measures: Motor development assessment, respiratory and cardiac examination.

Conditions

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Spinal Muscular Atrophy Muscular Dystrophy Muscle Diseases Myasthenic Syndromes Polyneuropathies

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Neuromuscular diseases

Prospective cohort of children with inherited or acquired neuromuscular diseases.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Weakness, hypotonia.
* Nerve conduction study and electromyographic confirmation of lower motor neuron affection.

Exclusion Criteria

* Chromosomal diseases.
* Malformations and deformations.
Minimum Eligible Age

1 Month

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ain Shams University

OTHER

Sponsor Role lead

Responsible Party

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Sahar M.A. Hassanein, MD

Professor of Pediatrics

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Sahar MA Hassanein, MD, PhD

Role: STUDY_CHAIR

Pediatric Department, Children's Hospital, Faculty of Medicine, Ain Shams University

Locations

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Pediatric Department, Children's Hospital, Faculty of Medicine, Ain Shams University

Cairo, Abassia, Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Sahar MA Hassanein, MD, PhD

Role: CONTACT

201223183943

Facility Contacts

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Mohsen S Elalfy, MD, PhD

Role: primary

Related Links

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http://med.asu.edu.eg/

Faculty of Medicine, Ain Shams University website

http://www.asu.edu.eg/

Ain Shams University web site

Other Identifiers

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EGYPT PED-NMD 2014

Identifier Type: -

Identifier Source: org_study_id

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