Pigtail Catheter: a Less Invasive Option for Pleural Drainage of Recurrent Hepatic Hydrothorax
NCT ID: NCT02119169
Last Updated: 2017-12-27
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
30 participants
INTERVENTIONAL
2014-03-31
2022-12-31
Brief Summary
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Detailed Description
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HH is an infrequent but a well-known complication of portal hypertension. Trans-diaphragmatic passage of ascitic fluid from peritoneal to the pleural cavity through numerous diaphragmatic defects has been shown to be the predominant mechanism in the formation of HH (Kumar\&Kumar, 2014).
Patients with hepatic hydrothoraces often have few options (Goto et al., 2011). Diuretic-resistant HH could be managed with liver transplantation, transjugular intrahepatic portosystemic shunt (TIPS) or indwelling pleural catheters. However, tube thoracotomy and pleurodesis failed in most patients (Singh et al., 2013).
Case reports and small case series have reported a high rate of complications associated with chest tube placement for hepatic hydrothorax. The most common reported complications were acute kidney injury, pneumothorax, and empyema. Death has been recorded in some cases. Chest tube insertion for hepatic hydrothorax carries significant morbidity and mortality, with questionable benefit (Orman\&Lok, 2009).
Pigtail catheter insertion is an effective and safe method of draining pleural fluid. Its use is safe and recommended for all cases of pleural effusion requiring chest drain except for empyema and other loculated effusions that yielded low success rate (Bediwy and Amer, 2012).
Conditions
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Study Design
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NA
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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pigtail catheter
Pigtail catheter for pleural drainage of recurrent hepatic hydrothorax
Pigtail catheter
pigtail catheter for pleural drainage
Interventions
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Pigtail catheter
pigtail catheter for pleural drainage
Eligibility Criteria
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Inclusion Criteria
* Pleural fluid should be transudate according to Light's criteria:
* Pleural fluid-to-serum protein ratio less than 0.5
* Pleural fluid lactic dehydrogenase (LDH) less than 200 IU
* Pleural fluid-to-serum LDH ratio and pleural fluid-to-high normal serum LDH ratio less than 0.6
Exclusion Criteria
* Congestive heart failure.
* Recent (i.e. within the previous 2 weeks) episode of digestive hemorrhage.
* Exudative pleural effusion.
* Ascitic fluid or pleural fluid infection
* Platelet count below 50,000
* Prothrombin activity below 50%
18 Years
70 Years
ALL
No
Sponsors
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Tanta University
OTHER
Sherief Abd-Elsalam
OTHER
Responsible Party
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Sherief Abd-Elsalam
doctor
Principal Investigators
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Mohamed A. Sharaf-Eldin, professor
Role: PRINCIPAL_INVESTIGATOR
TUH
Adel S Bediwy, Professor
Role: STUDY_DIRECTOR
TUH
Sherief M Abd-Elsalam, Doctor
Role: STUDY_CHAIR
TUH
Abdelrahman a kobtan, doctor
Role: STUDY_CHAIR
TUH
Locations
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Tanta university hospital
Tanta, , Egypt
Countries
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Central Contacts
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Facility Contacts
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Abd-Elsalam
Role: primary
References
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Sharaf-Eldin M, Bediwy AS, Kobtan A, Abd-Elsalam S, El-Kalla F, Mansour L, Elkhalawany W, Elhendawy M, Soliman S. Pigtail Catheter: A Less Invasive Option for Pleural Drainage in Egyptian Patients with Recurrent Hepatic Hydrothorax. Gastroenterol Res Pract. 2016;2016:4013052. doi: 10.1155/2016/4013052. Epub 2016 Jun 2.
Other Identifiers
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Tanta university hospital
Identifier Type: OTHER_GRANT
Identifier Source: secondary_id
Mohamed Sharaf-Eldin
Identifier Type: -
Identifier Source: org_study_id