Mathematical Model for the Human Menstrual Cycle, Endocrinological Diseases and Fertility Treatment-PAEON

NCT ID: NCT02098668

Last Updated: 2016-09-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

123 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-09-30

Study Completion Date

2016-04-30

Brief Summary

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Development of a bio-mathematical model of the human female cycle

Detailed Description

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From hormonal measurements throughout 1-2 menstrual cycles in women with and without endocrinological pathology a mathematical model of the human menstrual cycle will be generated. The model will serve to predict development of the cycle including ovulation as well as to better understand the pathophysiology of endocrinological disorder. In a second step current treatment protocols for fertility treatment will be integrated into the model in order to optimize treatment outcome.

Conditions

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Polycystic Ovary Syndrome Endometriosis Hyperprolactinemia

Study Design

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Study Time Perspective

PROSPECTIVE

Study Groups

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Normal, pathological cycle, infertility

healthy women PCOS Endometriosis hyperprolactinemia fertility treatment

Fertility treatment

Intervention Type OTHER

Fertility treatment

Interventions

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Fertility treatment

Fertility treatment

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

\- Women during their reproductive phase, no hormonal therapy

Exclusion Criteria

\- Amenorrhoae
Minimum Eligible Age

18 Months

Maximum Eligible Age

43 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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University of Zurich

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Brigitte Leeners, MD

Role: PRINCIPAL_INVESTIGATOR

University Hospital Zurich, Division of Reproductive Endocrinology

Locations

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University Hospital Zurich, Division of Reproductive Endocrinology

Zurich, Canton of Zurich, Switzerland

Site Status

Countries

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Switzerland

References

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Leeners B, Kruger THC, Geraedts K, Tronci E, Mancini T, Egli M, Roblitz S, Saleh L, Spanaus K, Schippert C, Zhang Y, Ille F. Associations Between Natural Physiological and Supraphysiological Estradiol Levels and Stress Perception. Front Psychol. 2019 Jun 11;10:1296. doi: 10.3389/fpsyg.2019.01296. eCollection 2019.

Reference Type DERIVED
PMID: 31244718 (View on PubMed)

Other Identifiers

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17721_PAEON

Identifier Type: -

Identifier Source: org_study_id

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