Study to Evaluate the Sexual Functioning of Healthy Adults After Receiving Vilazodone, Paroxetine or Placebo

NCT ID: NCT02097147

Last Updated: 2015-02-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

202 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-03-31

Study Completion Date

2014-11-30

Brief Summary

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To compare the effects of vilazodone, paroxetine and placebo on sexual function in sexually active healthy adults.

Detailed Description

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Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Vilazodone 20 mg

Vilazodone 10 mg once daily for 7 days, followed by vilazodone 20 mg once daily for 28 days.

Group Type EXPERIMENTAL

Vilazodone 20 mg

Intervention Type DRUG

Oral administration, once per day.

Vilazodone 40 mg

Vilazodone 10 mg once daily for 7 days, followed by vilazodone 20 mg once daily for 7 days, followed by vilazodone 40 mg once daily for 21 days

Group Type EXPERIMENTAL

Vilazodone 40 mg

Intervention Type DRUG

Oral administration, once per day.

Paroxetine 20 mg

Paroxetine 10 mg once daily for 7 days, followed by paroxetine 20 mg for 28 days

Group Type ACTIVE_COMPARATOR

Paroxetine 20 mg

Intervention Type DRUG

Oral administration, once per day.

Placebo

Placebo once daily for 35 days

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

Oral administration, once per day.

Interventions

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Vilazodone 20 mg

Oral administration, once per day.

Intervention Type DRUG

Vilazodone 40 mg

Oral administration, once per day.

Intervention Type DRUG

Paroxetine 20 mg

Oral administration, once per day.

Intervention Type DRUG

Placebo

Oral administration, once per day.

Intervention Type DRUG

Other Intervention Names

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Viibyrd Viibryd Paxil

Eligibility Criteria

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Inclusion Criteria

* Healthy male or female, aged 18 through 45 years, inclusive
* Currently sexually active
* If female, non pregnant and agree to use acceptable for of contraception during
* If male, be sterile or have partner use contraception.

Exclusion Criteria

* Have sexual dysfunction
* Have history of diagnosis or treatment of any disorder related to sexual functioning.
* Clinically significant disease state, in the opinion of the examining physician, in any body system
* History of alcohol or other substance abuse or dependence within the previous 5 years
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Forest Laboratories

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Maju Mathews, MD

Role: STUDY_DIRECTOR

Forest Laboratories

Locations

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Forest Investigative Site 001

Miami, Florida, United States

Site Status

Forest Investigative Site 002

Overland Park, Kansas, United States

Site Status

Forest Investigative Site 003

Saint Paul, Minnesota, United States

Site Status

Forest Investigative Site 004

Charlottesville, Virginia, United States

Site Status

Countries

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United States

Other Identifiers

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VLZ-MD-24

Identifier Type: -

Identifier Source: org_study_id

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