Safety and Effectiveness Study of the Precision SCS Systems Adapted for High-Rate Spinal Cord Stimulation

NCT ID: NCT02093793

Last Updated: 2020-11-13

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

383 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-03-27

Study Completion Date

2019-08-29

Brief Summary

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To evaluate the safety and effectiveness of the Precision Spinal Cord Stimulator Systems Adapted for High-Rate Spinal Cord Stimulation as an aid in the management of chronic intractable pain

Detailed Description

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To evaluate the safety and effectiveness of high rate spinal cord stimulation (HR-SCS) therapy as an aid in the management of chronic intractable pain of the trunk using the Boston Scientific (BSC) PRECISION Spinal Cord Stimulator Systems Adapted for High-Rate Spinal Cord Stimulation

Conditions

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Chronic Pain Back Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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High Rate Spinal Cord Stimulation

PRECISION SCS Adapted for High-Rate SCS

Group Type EXPERIMENTAL

PRECISION SCS Adapted for High-Rate SCS

Intervention Type DEVICE

Comparison of spinal cord stimulation parameters

Commercial Rate Spinal Cord Stimulation

PRECISION SCS Adapted for High-Rate SCS

Group Type ACTIVE_COMPARATOR

PRECISION SCS Adapted for High-Rate SCS

Intervention Type DEVICE

Comparison of spinal cord stimulation parameters

Interventions

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PRECISION SCS Adapted for High-Rate SCS

Comparison of spinal cord stimulation parameters

Intervention Type DEVICE

Other Intervention Names

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Boston Scientific PRECISION Spinal Cord Stimulator System

Eligibility Criteria

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Inclusion Criteria

* Have been diagnosed with chronic, intractable pain of the trunk (NRS ≥ 5) which has been refractory to conservative therapy for a minimum of 90 days.
* Be an appropriate candidate for the surgical procedures required in this study based on the clinical judgment of the implanting physician
* Be 22 years of age or older at the time of enrollment
* Be willing and capable of giving informed consent
* Be willing and able to comply with study-related requirements, procedures, and visits

Exclusion Criteria

* Have a medical condition or pain in other area(s), not intended to be treated with SCS, that could interfere with study procedures, accurate pain reporting, and/or confound evaluation of study endpoints, as determined by the Investigator
* Have evidence of an active disruptive psychological or psychiatric disorder or other known condition significant enough to impact perception of pain, compliance of intervention and/or ability to evaluate treatment outcome, as determined by a psychologist
* Have previous spinal cord stimulation trial or is already implanted with an active implantable device(s) (e.g. pacemaker, drug pump, implantable pulse generator)
* Have a current systemic infection, or local infection in close proximity to anticipated surgical field
* Pregnant or plan to get pregnant during the course of the study or not using adequate contraception.
* Be participating in another clinical study that may influence the data collected for the study
Minimum Eligible Age

22 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Boston Scientific Corporation

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Mark Wallace, M.D.

Role: PRINCIPAL_INVESTIGATOR

University of California, San Diego

Locations

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Hope Research Institute

Phoenix, Arizona, United States

Site Status

Coastal Pain & Spinal Diagnostics

Carlsbad, California, United States

Site Status

UCSD Medical Center - Jacobs Medical Center

La Jolla, California, United States

Site Status

San Diego Pain Institute

San Diego, California, United States

Site Status

Compass Research, LLC

Orlando, Florida, United States

Site Status

Rush University Medical Center

Chicago, Illinois, United States

Site Status

Willis-Knighton River Cities Clinical Research Center

Shreveport, Louisiana, United States

Site Status

MAPS Applied Research Center

Edina, Minnesota, United States

Site Status

Mayo Clinic Foundation

Rochester, Minnesota, United States

Site Status

Mercy Medical Research Institute

Springfield, Missouri, United States

Site Status

Hope Research Institute

Las Vegas, Nevada, United States

Site Status

Premier Pain Centers, LLC

Shrewsbury, New Jersey, United States

Site Status

The Center for Clinical Research, LLC

Winston-Salem, North Carolina, United States

Site Status

University Hospitals of Cleveland

Cleveland, Ohio, United States

Site Status

Pacific Sports and Spine, LLC

Eugene, Oregon, United States

Site Status

Pain Consultants of Oregon

Eugene, Oregon, United States

Site Status

Oregon Health Sciences University

Portland, Oregon, United States

Site Status

Oregon Neurosurgery

Springfield, Oregon, United States

Site Status

Precision Spine Care

Tyler, Texas, United States

Site Status

Pacific Medical Center

Seattle, Washington, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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A4007

Identifier Type: -

Identifier Source: org_study_id