Tooth Loss in Periodontitis Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-06-30

Study Completion Date

2020-12-31

Brief Summary

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Tooth loss in periodontitis patients is associated with patient and site factors as well as with treatment provided. Not much is known about long-term tooth loss in periodontitis patients in private practice in the UK. The study plans to follow-up 200 subjects with periodontitis (and currently on maintenance therapy) for 5 years. The effect of treatment provided, site and patient risk factors on tooth loss will be studied.

Detailed Description

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Conditions

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Periodontitis

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

1. Initial diagnosis of chronic or aggressive periodontitis (Lindhe et al. 1999, Lang et al. 1999), with at least two sites with PPD and CAL ≥5mm
2. Diagnosed and treated by the same periodontist (LN)
3. Willing to give written informed consent for study participation
4. Willing to undergo SPT as per standard of care for at least 5 years

Exclusion Criteria

1. Serious medical history that prevents patients from undergoing dental treatment
2. History of rheumatic fever, heart murmur, mitral valve prolapse, artificial heart valve or other conditions requiring prophylactic antibiotic coverage prior to invasive dental procedures
3. Current alcohol or drug abuse
4. Self-reported pregnancy or lactation
5. Other severe acute or chronic medical or psychiatric condition or laboratory abnormality that may compromise trial participation and/or interpretation of trial results and, in the judgement of the investigator, would make the subject inappropriate for entry into this trial

Minimum Eligible Age

16 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Luigi Nibali, PhD

Role: PRINCIPAL_INVESTIGATOR

UCL

Locations

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The Dentist

Bishop's Stortford, Herts, United Kingdom

Site Status

Ravenscourt Dental Practice

London, , United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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UCL 14/0110

Identifier Type: -

Identifier Source: org_study_id