Panitumumab for Intravenous Infusion 100 mg and 400 mg Special Drug Use Surveillance "Survey on Unresectable, Advanced or Recurrent Colorectal Cancer With Wild-type KRAS Gene" (All-patient Surveillance)

NCT ID: NCT02089737

Last Updated: 2017-04-06

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

3091 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-06-30

Study Completion Date

2012-07-31

Brief Summary

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The efficacy and safety of panitumumab (Vectibix) in the routine clinical setting will be studied.

Specifically, information will be collected on the following as events of interest: skin disorders, interstitial lung disease, infusion reactions, electrolyte abnormalities, and cardiac disorders.

Detailed Description

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The efficacy and safety of panitumumab (Vectibix) in the routine clinical setting will be studied.

Participants of this surveillance will be patients with unresectable, advanced or recurrent colorectal cancer with the wild-type KRAS gene. The planned sample size is 2,000 patients.

The usual adult dosage is 6 mg/kg of panitumumab given by intravenous drip infusion over a 60-minute period once every 2 weeks. The dosage may also be reduced as needed, depending on the patient's condition.

Conditions

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Advanced or Recurrent Colorectal Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Panitumumab 6 mg/kg

Panitumumab 6 mg/kg, intravenous drip infusion over a 60-minute period, once every 2 weeks

Panitumumab

Intervention Type DRUG

Panitumumab for intravenous infusion

Interventions

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Panitumumab

Panitumumab for intravenous infusion

Intervention Type DRUG

Other Intervention Names

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Vectibix

Eligibility Criteria

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Inclusion Criteria

* Unresectable, advanced or recurrent colorectal cancer with wild-type KRAS gene

Exclusion Criteria

* Patients with a medical history of severe hypersensitivity to any of the ingredients of Vectibix
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Takeda

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Postmarketing Group Manager

Role: STUDY_CHAIR

Takeda

Other Identifiers

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JapicCTI-132374

Identifier Type: REGISTRY

Identifier Source: secondary_id

JapicCTI-R140654

Identifier Type: REGISTRY

Identifier Source: secondary_id

183-011

Identifier Type: -

Identifier Source: org_study_id

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