C1q/TNF-related Proteins in Non-Alcoholic Fatty Liver Disease

NCT ID: NCT02083159

Last Updated: 2016-09-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-03-31

Brief Summary

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Non-alcoholic fatty liver disease (NAFLD) is characterized by an accumulation of fat in the liver, which is one of the most common forms of chronic liver disease in developed countries. In western countries, the prevalence of NAFLD in the general population is estimated to be 20-30%; in obese populations, this increases to 57.5-74%. But, it hasn't been clearly elucidated yet regarding the underlying disease pathophysiology and treatmet strategy.

Recently, members of the C1q/tumor necrosis factor-related protein (CTRP) family have been reported to share structural homology with adiponectin. To date, 15 CTRP family members have been found that might play major roles in glucose metabolism and inflammation.

The investigators tried to clarify the relationship between CTRP family and NAFLD in Korean men and women.

Detailed Description

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Conditions

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NAFLD

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients with NAFLD

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* 20\<age\<80
* apparently healthy subjects

Exclusion Criteria

* a history of CVD
* diabetes
* stage 2 hypertension
* malignancy
* severe renal or hepatic disease
Minimum Eligible Age

20 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Korea University

OTHER

Sponsor Role lead

Responsible Party

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Kyung Mook Choi

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Korea Univ. Guro Hospital

Seoul, , South Korea

Site Status RECRUITING

Countries

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South Korea

Central Contacts

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Ho Cheol Hong, M.D.

Role: CONTACT

822-2626-3044

Kyung Mook Choi, M.D.

Role: CONTACT

822-2626-3043

Facility Contacts

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Ho Cheol Hong, M.D.

Role: primary

822-2626-3044

Kyung Mook Choi, M.D.

Role: backup

822-2626-3043

Other Identifiers

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NAFLD(CTRP)

Identifier Type: -

Identifier Source: org_study_id

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