Insulin Dosing in Diabetic Patients With End Stage Renal Disease (ESRD) or Hemodialysis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

496 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-10-01

Study Completion Date

2017-05-17

Brief Summary

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The purpose of this study is to assess whether the current recommendation for a 50% dose reduction in insulin for diabetic patients with a creatinine clearance (CrCl) ≤15 mL/min or on hemodialysis results in an increased number of hypoglycemic episodes.

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Detailed Description

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Conditions

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Diabetes Hypoglycemia Renal Dysfunction Insulin Dosing

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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End Stage Renal Disease

GFR 15 ml/min or less or on Dialysis

No interventions assigned to this group

Chronic Kidney Disease Stage 4

GFR 15-30 ml/min

No interventions assigned to this group

Chronic Kidney Disease Stage -3

GFR 30-60 ml/min

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Inpatient men and women 18 years of age and older with a diagnosis of type 2 diabetes mellitus (T2DM) with CrCl ≥60, 16-59 or ≤15 milliliters/minute.