Prophylactic Antibiotic in Treatment of Fingertip Amputation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-01-31

Study Completion Date

2015-02-28

Brief Summary

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Fingertip amputation is a common injury. Considerable controversy exists as to whether prophylactic antibiotics are necessary for this injury. The investigators goal was to compare the rate of infections among subgroups with and without prophylactic antibiotic treatment. The study hypothesis was that infection rates were similar in the two groups.

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Detailed Description

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Conditions

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Infection Rate After Fingertip Amputation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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no antibiotic

Group Type NO_INTERVENTION

No interventions assigned to this group

Cephazolin

cefazoline

Group Type ACTIVE_COMPARATOR

Cephazolin

Intervention Type DRUG

Cephazolin

Interventions

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Cephazolin

Intervention Type DRUG

Other Intervention Names

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Cefamezine

Eligibility Criteria

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Inclusion Criteria

* fingertip amputation with bone exposed

Exclusion Criteria

* under the age of 18 years
* if the patient had diabetes
* oncological disorder
* immune deficiency
* bleeding disorder
* used steroids regularly
* presented with a grossly contaminated wound or other injury requiring antibiotic treatment
* were currently taking antibiotics, or had a previous allergic reaction to cephalosporins.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes