Trial Outcomes & Findings for Obtain Additional Information on Use of CorMatrix ECM (Extracellular Matrix) (NCT NCT02073331)

NCT ID: NCT02073331

Last Updated: 2023-07-21

Results Overview

Data will be collected at the initial post-operative visit. This is a single visit study.

Recruitment status

COMPLETED

Target enrollment

1420 participants

Primary outcome timeframe

Post-op visit, after an average of 30 days

Results posted on

2023-07-21

Participant Flow

Participant milestones

Participant milestones
Measure
CorMatrix ECM
Data collection for information on the use of CorMatrix ECM for pericardial reconstruction
Overall Study
STARTED
1420
Overall Study
COMPLETED
1420
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Obtain Additional Information on Use of CorMatrix ECM (Extracellular Matrix)

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
CorMatrix ECM
n=1 Participants
Data collection for information on the use of CorMatrix ECM for pericardial reconstruction
Age, Categorical
<=18 years
0 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
845 Participants
n=5 Participants
Age, Categorical
>=65 years
575 Participants
n=5 Participants
Age, Continuous
61.3 years
STANDARD_DEVIATION 11.9 • n=5 Participants
Sex: Female, Male
Female
376 Participants
n=5 Participants
Sex: Female, Male
Male
1,044 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
118 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
1,302 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants
Race (NIH/OMB)
American Indian or Alaska Native
7 Participants
n=5 Participants
Race (NIH/OMB)
Asian
18 Participants
n=5 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
3 Participants
n=5 Participants
Race (NIH/OMB)
Black or African American
158 Participants
n=5 Participants
Race (NIH/OMB)
White
1,088 Participants
n=5 Participants
Race (NIH/OMB)
More than one race
141 Participants
n=5 Participants
Race (NIH/OMB)
Unknown or Not Reported
5 Participants
n=5 Participants
Region of Enrollment
United States
1,420 participants
n=5 Participants
Pre-Operative Risk Factors
Hypertension
1,138 Risk factors
n=5 Participants
Pre-Operative Risk Factors
Hypercholesterolemia
727 Risk factors
n=5 Participants
Pre-Operative Risk Factors
Diabetes Mellitus
531 Risk factors
n=5 Participants
Pre-Operative Risk Factors
Smoking
357 Risk factors
n=5 Participants
Pre-Operative Risk Factors
Prior Myocardial Infarction
242 Risk factors
n=5 Participants
Pre-Operative Risk Factors
Congestive Heart Failure
226 Risk factors
n=5 Participants
Pre-Operative Risk Factors
Chronic Obstructive Pulmonary Disease
158 Risk factors
n=5 Participants
Pre-Operative Risk Factors
Prior Percutaneous Coronary Intervention
126 Risk factors
n=5 Participants
Pre-Operative Risk Factors
Chronic Renal Failure
70 Risk factors
n=5 Participants
Pre-Operative Risk Factors
Prior Cerebrovascular Accident
60 Risk factors
n=5 Participants
Index Procedure
Isolated CABG
923 Participants
n=5 Participants
Index Procedure
Valve Repair/Replacement
300 Participants
n=5 Participants
Index Procedure
CABG & Valve Repair/Replacement
136 Participants
n=5 Participants
Index Procedure
Other
61 Participants
n=5 Participants

PRIMARY outcome

Timeframe: Post-op visit, after an average of 30 days

Data will be collected at the initial post-operative visit. This is a single visit study.

Outcome measures

Outcome measures
Measure
CorMatrix ECM
n=1 Participants
Data collection for information on the use of CorMatrix ECM for pericardial reconstruction
Proportion of Subjects With Device Related Adverse Events.
0 Proportion of subjects
Interval 0.0 to 0.0

Adverse Events

CorMatrix ECM

Serious events: 0 serious events
Other events: 0 other events
Deaths: 8 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Clinical Director

Aziyo Biologics, Inc.

Phone: 510-730-7973

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place

Restriction type: GT60