Trial Outcomes & Findings for Cast vs. Splints for Minimally Displaced Distal Radius Fractures in the Elderly (NCT NCT02066857)

NCT ID: NCT02066857

Last Updated: 2017-05-24

Results Overview

Wrist ROM will be assessed by a goniometer exam.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

5 participants

Primary outcome timeframe

Baseline, Month 3

Results posted on

2017-05-24

Participant Flow

Participants were recruited from the Emory Orthopaedic Fracture Clinic from April 2014 to November 2014.

Participant milestones

Participant milestones
Measure
Generic Plaster or Fiberglass Cast Group
Participants were randomized to receive a generic plaster or fiberglass cast for treatment of non-displaced distal radius fracture for 6 weeks.
Generic "Off the Shelf" Removable Splint Group
Participants were randomized to receive a generic "off the shelf" removable splint for treatment of non-displaced distal radius fracture for 6 weeks.
Overall Study
STARTED
1
4
Overall Study
COMPLETED
0
3
Overall Study
NOT COMPLETED
1
1

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Cast vs. Splints for Minimally Displaced Distal Radius Fractures in the Elderly

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Generic Plaster or Fiberglass Cast Group
n=1 Participants
Participants were randomized to receive a generic plaster or fiberglass cast for treatment of non-displaced distal radius fracture for 6 weeks.
Generic "Off the Shelf" Removable Splint Group
n=4 Participants
Participants were randomized to receive a generic "off the shelf" removable splint for treatment of non-displaced distal radius fracture for 6 weeks.
Total
n=5 Participants
Total of all reporting groups
Age, Categorical
<=18 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
1 Participants
n=5 Participants
1 Participants
n=7 Participants
2 Participants
n=5 Participants
Age, Categorical
>=65 years
0 Participants
n=5 Participants
3 Participants
n=7 Participants
3 Participants
n=5 Participants
Sex: Female, Male
Female
0 Participants
n=5 Participants
4 Participants
n=7 Participants
4 Participants
n=5 Participants
Sex: Female, Male
Male
1 Participants
n=5 Participants
0 Participants
n=7 Participants
1 Participants
n=5 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Race (NIH/OMB)
Asian
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Race (NIH/OMB)
Black or African American
1 Participants
n=5 Participants
2 Participants
n=7 Participants
3 Participants
n=5 Participants
Race (NIH/OMB)
White
0 Participants
n=5 Participants
2 Participants
n=7 Participants
2 Participants
n=5 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Region of Enrollment
United States
1 Participants
n=5 Participants
4 Participants
n=7 Participants
5 Participants
n=5 Participants

PRIMARY outcome

Timeframe: Baseline, Month 3

Population: Data for this outcome measure are not available for analysis.

Wrist ROM will be assessed by a goniometer exam.

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: Baseline, Week 2, Week 6, Week 12

Population: Of the 5 participants who were enrolled, data were analyzed for the 3 participants who completed all study visits.

The Mayo Wrist Score is a clinician-completed scoring system used to evaluate the level of functionality in the wrist, assessing pain, functional status (able to work), range of motion and grip strength. Total scores for functionality range from 0-100 and are categorized as follows: 90-100 indicates excellent, 80-90 indicates good, 60-80 indicates satisfactory, below 60 indicates poor. The assessment was completed at all study visits.

Outcome measures

Outcome measures
Measure
Generic Plaster or Fiberglass Cast Group
n=3 Participants
Participants were randomized to receive a generic plaster or fiberglass cast for treatment of non-displaced distal radius fracture for 6 weeks.
Generic "Off the Shelf" Removable Splint Group
Participants were randomized to receive a generic "off the shelf" removable splint for treatment of non-displaced distal radius fracture for 6 weeks.
Mean Mayo Wrist Score
Baseline
31.67 units on a scale
Standard Deviation 16.07
Mean Mayo Wrist Score
Week 2
46.67 units on a scale
Standard Deviation 20.21
Mean Mayo Wrist Score
Week 6
65 units on a scale
Standard Deviation 10
Mean Mayo Wrist Score
Week 12
78.33 units on a scale
Standard Deviation 2.89

PRIMARY outcome

Timeframe: Baseline, Month 3

Population: Data for this outcome measure are not available for analysis.

Grip strength will be assessed by bilateral dynamometer testing.

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: Duration of Study (Up to 3 Months)

Population: Of the 5 participants who were enrolled, data were analyzed for the 3 participants who completed all study visits.

The number of participants who experienced treatment related complications including the need for manipulation in the case of lost reduction.

Outcome measures

Outcome measures
Measure
Generic Plaster or Fiberglass Cast Group
n=3 Participants
Participants were randomized to receive a generic plaster or fiberglass cast for treatment of non-displaced distal radius fracture for 6 weeks.
Generic "Off the Shelf" Removable Splint Group
Participants were randomized to receive a generic "off the shelf" removable splint for treatment of non-displaced distal radius fracture for 6 weeks.
Complication Rate
0 Participants

PRIMARY outcome

Timeframe: Baseline, Week 2, Week 6, Week 12

Population: Of the 5 participants who were enrolled, data were analyzed for the 3 participants who completed all study visits.

Pain will be assessed by a visual analog scale (VAS). Participants rate their pain level in a scale from 0 to 10; 0 representing "no pain" and 10 representing "the worst pain imaginable". The assessment was completed at all study visits.

Outcome measures

Outcome measures
Measure
Generic Plaster or Fiberglass Cast Group
n=3 Participants
Participants were randomized to receive a generic plaster or fiberglass cast for treatment of non-displaced distal radius fracture for 6 weeks.
Generic "Off the Shelf" Removable Splint Group
Participants were randomized to receive a generic "off the shelf" removable splint for treatment of non-displaced distal radius fracture for 6 weeks.
Mean Pain Score
Baseline
6 units on a scale
Standard Deviation 3.46
Mean Pain Score
Week 2
3.66 units on a scale
Standard Deviation 3.06
Mean Pain Score
Week 6
1.67 units on a scale
Standard Deviation 1.53
Mean Pain Score
Week 12
.33 units on a scale
Standard Deviation .58

SECONDARY outcome

Timeframe: Baseline, Week 2, Week 6, Week 12

Population: Of the 5 participants who were enrolled, data were analyzed for the 3 participants who completed all study visits.

The DASH questionnaire asks about symptoms as well as ability to perform certain activities. Scores range on a 0-100 scale. A higher score indicates greater disability.

Outcome measures

Outcome measures
Measure
Generic Plaster or Fiberglass Cast Group
n=3 Participants
Participants were randomized to receive a generic plaster or fiberglass cast for treatment of non-displaced distal radius fracture for 6 weeks.
Generic "Off the Shelf" Removable Splint Group
Participants were randomized to receive a generic "off the shelf" removable splint for treatment of non-displaced distal radius fracture for 6 weeks.
Mean Disabilities of the Arm and Shoulder (DASH) Questionnaire Score
Baseline
73.03 units on a scale
Standard Deviation 23.53
Mean Disabilities of the Arm and Shoulder (DASH) Questionnaire Score
Week 2
38.63 units on a scale
Standard Deviation 27.11
Mean Disabilities of the Arm and Shoulder (DASH) Questionnaire Score
Week 6
23.33 units on a scale
Standard Deviation 22.50
Mean Disabilities of the Arm and Shoulder (DASH) Questionnaire Score
Week 12
11.67 units on a scale
Standard Deviation 16.07

SECONDARY outcome

Timeframe: Baseline, Month 3

Population: No participants completed this survey as this outcome measure was removed from the protocol. No data were collected.

The SF-12 QOL is a self-administered measure asking views about participant's health and how well they are able to perform usual activities.

Outcome measures

Outcome data not reported

Adverse Events

Generic Plaster or Fiberglass Cast Group

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Generic "Off the Shelf" Removable Splint Group

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Claude Jarrett, M.D.

Emory University

Phone: 404-778-8099

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place