Prognostic Relevance of Biological Subtype in Breast Cancer

NCT ID: NCT02063906

Last Updated: 2017-05-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

202 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-02-28

Study Completion Date

2019-05-31

Brief Summary

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Recently, the investigators face "on the edges" for treatment decision to decide adjuvant systemic treatment, especially for patients who show discordance between stage and tumor biology. The aim of this study was to compare the prognostic relevance of the TNM staging system and intrinsic subtype in breast cancer patients who received curative surgery.

Detailed Description

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Identified patients who received curative surgery for stage I-III breast cancer and had available data on immunohistochemistry profiles including hormone receptor status (HR) status, human epidermal growth factor receptor 2 (HER2) status, and Ki 67 staining at Samsung Medical Center from January 2004 to September 2008. Primary outcomes were recurrence-free survival (RFS) and overall survival (OS).

Conditions

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Breast Cancer

Study Design

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Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Study Groups

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Breast cancer stage I-III

who received curative surgery for stage I-III breast cancer and had available data on immunohistochemistry profiles including hormone receptor status (HR) status, human epidermal growth factor receptor 2 (HER2) status, and Ki 67 staining at Samsung Medical Center from January 2004 to September 2008.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* patients who received curative surgery
* stage I-III breast cancer
* between January 2004 and September 2008
* had available immunohistochemistry profiles.

Exclusion Criteria

* age \<18 years old
* microinvasive carcinoma of breast
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Samsung Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Young-Hyuck Im

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Young-Hyuck Im, Pf

Role: PRINCIPAL_INVESTIGATOR

Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine

Locations

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Samsung Medical Center, Sungkyunkwan University School of Medicine

Seoul, , South Korea

Site Status RECRUITING

Countries

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South Korea

Central Contacts

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Young-Hyuck Im, MD, PhD

Role: CONTACT

Facility Contacts

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Young-Hyuck Im, MD, PhD

Role: primary

+82-2-3410-3445

Other Identifiers

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2014-02-045

Identifier Type: -

Identifier Source: org_study_id

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