Dissemination of the Look Ahead Weight Management Treatment in the Military

NCT ID: NCT02063178

Last Updated: 2019-02-28

Study Results

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

248 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-01-06

Study Completion Date

2018-06-30

Brief Summary

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Purpose: This study aims to take the procedural and research-based lessons learned from a pilot weight loss intervention (IRB # 13-02563-XP), conducted by The University of Tennessee Health Science Center in 2013, and apply them to the current study of 204 active duty military personnel. The pilot study translated and tailored the Look Ahead weight loss intervention to an overweight/obese active duty U.S. Air Force population, while accommodating the lifestyle and environment that is unique to military members and evaluate materials and procedures used.

Rationale: Being overweight is now by far the leading medical reason for rejection in the military. Unfortunately, the impact of weight problems on the military does not stop with those turned away from military service. From 1998 to 2008, the Armed Forces Health Surveillance Center reported the percent of active military members who experienced medical encounters for overweight or obesity significantly increased. The estimated total days of work lost from absenteeism associated with active-duty personnel who are overweight or obese was 658,000. Using Department of Defense (DOD) estimates of average daily based, it was estimated that overweight and obesity costs the DOD $103 million dollars in health care costs annually. Note this estimate is for active duty personnel only. Furthermore, obesity is a major cause for the discharge of uniformed personnel.

The current study is inspired by the successful Look Ahead trial, a behavioral science obesity intervention treatment program that included: a collaborative approach, education, behavioral support, and motivational interviewing. The unique nature of this weight reduction study is significant. To our knowledge, there had not been a successful translation of a highly efficacious obesity treatment in the military until The University of Tennessee Health Science Center implemented a pilot version of the Fit Blue program for active duty U.S. Air Force members in 2013. Following a successful pilot and extant results from the Look Ahead trial, Investigators expect success during the full scale Fit Blue study.

Detailed Description

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This study is a weight loss intervention program tailored to a military population. Investigators will randomize 204 consented participants to either an intensive counselor-initiated weight loss intervention or a self-paced weight loss intervention. Neither of the aforementioned conditions are controls and both treatments are expected to result in weight reduction.

Procedures: This is a two-arm individually randomized trial. The Counselor-initiated group will follow a more intense counselor-initiated approach, where the counselor schedules weekly telephone sessions and contacts them directly. The Self-paced group uses a less intense approach, where the participants can receive the same telephone counseling sessions as the counselor-initiated group, only if they call the counselor.

Potential participants will be recruited through the use of advertisements, electronic bulletins, emails, newspapers, and word-of-mouth. Prior to randomization, interested individuals will complete a phone screening, informed consent, two in-person data collection visits and obtain medical clearance, as well as participate in 1 week of dietary and physical activity self-monitoring.

The randomized participants will spend the next year involved in study interventions (either the Counselor-Initiated intervention or the Self-Paced intervention), diet and exercise self-monitoring, daily weighing, and may also include telephone counseling sessions.

The follow-up data collection visits will occur at 4 and 12 months after randomization. At these visits, physical measurements will be collected (i.e. height, weight, abdominal circumference, blood pressure and heart rate) and participants will complete various questionnaires. A Quality of Life questionnaire will also be administered by study personnel.

Conditions

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Overweight Obesity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Counselor-Initiated

Participants will receive 28 telephone sessions over a 12 month period by interventionists trained in behavior change skills and motivational interviewing techniques. Participants will be asked to monitor food intake and physical activity using the LoseIt website/app and weight daily using a Body Trace e-scale. Participants will receive feedback on self-monitoring through e-mail. Dietary goals will be based on weight and participants' weight-loss progress. Participants will be encouraged to replace 2 meals and a snack with meal replacements (provided). Participants will be asked to gradually increase their moderate to vigorous exercise to 225-250 minutes per week. The Toolbox includes additional treatment options (e.g., food scales, exercise videos, cookbooks) for those who wish to take advantage of them. There will be several challenges that will provide a specific goal (e.g. increase self-monitoring), with a small award for completion.

Group Type EXPERIMENTAL

Phone-based sessions (28 total) on a structured schedule

Intervention Type BEHAVIORAL

28 sessions will be reviewed weekly and then bi-weekly with a trained motivational interviewing counselor for those individuals randomly assigned to the counselor-initiated condition.

Weight self-monitoring

Intervention Type BEHAVIORAL

Each randomized participant will be given a Body Trace scale that will electronically record their weight.

Dietary and physical activity self-monitoring

Intervention Type BEHAVIORAL

Each randomized participant will be given a free account to Lose It! Premium, an online food/activity diary for self-monitoring.

Scheduled tailored interventionist feedback

Intervention Type BEHAVIORAL

Randomly assigned participants to the counselor-initiated condition will receive feedback on their progress throughout their sessions with their assigned interventionist.

Dietary goals

Intervention Type BEHAVIORAL

Each randomized participant will receive a daily calorie goal range based on their current weight, gender, and BMI.

Meal replacements

Intervention Type BEHAVIORAL

Randomized participants will receive coupons for meal replacements including oatmeal and popcorn.

Physical activity goals

Intervention Type BEHAVIORAL

Each participant will complete the Global Physical Activity Questionnaire which will determine their weekly exercise goals.

Toolbox

Intervention Type BEHAVIORAL

The toolbox includes additional treatment options for those who wish to take advantage of them. Items may include: food scales, cookbooks, etc. These items may be checked out and must be returned prior to the completion of the study.

Challenges

Intervention Type BEHAVIORAL

There will be several challenges designed to increase participant interest and provide a specific goal (e.g., increase self-monitoring). Participants who successfully completed the challenges will be given a small award.

Self-Paced

The Self-paced group uses a less intense approach, where the participants can receive the same telephone counseling sessions as the counselor-initiated group, only if they call the counselor. Participants will be asked to monitor food intake and physical activity using the LoseIt website/app and weight daily using a Body Trace e-scale. Participants will receive feedback on self-monitoring through e-mail only upon request. Dietary goals will be based on weight and participants' weight-loss progress. Participants will be asked to gradually increase their moderate to vigorous exercise to 225-250 minutes per week.

Group Type ACTIVE_COMPARATOR

Phone-based sessions upon request

Intervention Type BEHAVIORAL

For those individuals randomly assigned to the self-paced condition, the 28 sessions are still available to them, the participant has to call to initiate sessions.

Weight self-monitoring

Intervention Type BEHAVIORAL

Each randomized participant will be given a Body Trace scale that will electronically record their weight.

Dietary and physical activity self-monitoring

Intervention Type BEHAVIORAL

Each randomized participant will be given a free account to Lose It! Premium, an online food/activity diary for self-monitoring.

Dietary goals

Intervention Type BEHAVIORAL

Each randomized participant will receive a daily calorie goal range based on their current weight, gender, and BMI.

Physical activity goals

Intervention Type BEHAVIORAL

Each participant will complete the Global Physical Activity Questionnaire which will determine their weekly exercise goals.

Tailored interventionist feedback upon request

Intervention Type BEHAVIORAL

Randomly assigned participants to the self-paced condition have the option to receive feedback on their progress upon request.

Interventions

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Phone-based sessions (28 total) on a structured schedule

28 sessions will be reviewed weekly and then bi-weekly with a trained motivational interviewing counselor for those individuals randomly assigned to the counselor-initiated condition.

Intervention Type BEHAVIORAL

Phone-based sessions upon request

For those individuals randomly assigned to the self-paced condition, the 28 sessions are still available to them, the participant has to call to initiate sessions.

Intervention Type BEHAVIORAL

Weight self-monitoring

Each randomized participant will be given a Body Trace scale that will electronically record their weight.

Intervention Type BEHAVIORAL

Dietary and physical activity self-monitoring

Each randomized participant will be given a free account to Lose It! Premium, an online food/activity diary for self-monitoring.

Intervention Type BEHAVIORAL

Scheduled tailored interventionist feedback

Randomly assigned participants to the counselor-initiated condition will receive feedback on their progress throughout their sessions with their assigned interventionist.

Intervention Type BEHAVIORAL

Dietary goals

Each randomized participant will receive a daily calorie goal range based on their current weight, gender, and BMI.

Intervention Type BEHAVIORAL

Meal replacements

Randomized participants will receive coupons for meal replacements including oatmeal and popcorn.

Intervention Type BEHAVIORAL

Physical activity goals

Each participant will complete the Global Physical Activity Questionnaire which will determine their weekly exercise goals.

Intervention Type BEHAVIORAL

Toolbox

The toolbox includes additional treatment options for those who wish to take advantage of them. Items may include: food scales, cookbooks, etc. These items may be checked out and must be returned prior to the completion of the study.

Intervention Type BEHAVIORAL

Challenges

There will be several challenges designed to increase participant interest and provide a specific goal (e.g., increase self-monitoring). Participants who successfully completed the challenges will be given a small award.

Intervention Type BEHAVIORAL

Tailored interventionist feedback upon request

Randomly assigned participants to the self-paced condition have the option to receive feedback on their progress upon request.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

1. Active duty military personnel at Joint Base San Antonio in the San Antonio, Texas area
2. BMI \> 25kg/m2
3. English speaking
4. Clearance by healthcare provider for participation in study
5. \>18 years of age
6. Participants have at least one year left on their duty assignment at enrollment

Exclusion Criteria

1. No access to a computer for self-monitoring in Lose It! or email feedback from counselor
2. Scheduled extended leave away from the San Antonio area in the next 13 months (i.e. planned Permanent Change of Station/Temporary Duty Assignment/deployment)
3. More than one failure of military-proctored physical fitness test on the last 12 months
4. Uncontrolled hypertension defined as Blood pressure \> 140/90
5. A member of the same household is already a FitBlue participant
6. Disability or condition that would limit physical activity
7. Current use of a weight loss medication
8. History of significant kidney or liver disease
9. History of uncontrolled thyroid disease or pheochromocytoma
10. Malignancy in last 5 years
11. History of diabetes treated with a medication that could cause hypoglycemia
12. Pregnancy, child birth within the last 6 months, breastfeeding for less than 6 months postpartum, or planning to become pregnant during the study follow-up time (12 months)
13. Presence of an unstable psychiatric condition
14. Severe asthma, bronchitis, or emphysema that precludes exercise
15. History of bariatric surgery or history of significant recent weight loss ( \> 10 pounds in past 3 months)
16. Other medical or behavioral factors that in the judgement of the Principal Investigator may interfere with study participation or the ability to follow the intervention protocol
17. History of cerebral, coronary, or peripheral vascular disease, uncontrolled cardiac arrhythmia, or uncontrolled congestive heart failure in past 12 months
18. Lack of access to telephone
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

Sponsor Role collaborator

United States Air Force

FED

Sponsor Role collaborator

University of Tennessee

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Rebecca Krukowski, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Tennessee

Locations

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Wilford Hall Ambulatory Surgical Center/Lackland Air Force Base

San Antonio, Texas, United States

Site Status

Countries

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United States

References

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Farage G, Simmons C, Kocak M, Klesges RC, Talcott GW, Richey P, Hare M, Johnson KC, Sen S, Krukowski R. Assessing the Contribution of Self-Monitoring Through a Commercial Weight Loss App: Mediation and Predictive Modeling Study. JMIR Mhealth Uhealth. 2021 Jul 14;9(7):e18741. doi: 10.2196/18741.

Reference Type DERIVED
PMID: 34259635 (View on PubMed)

Fahey MC, Klesges RC, Kocak M, Gladney LA, Talcott GW, Krukowski RA. Counselor Efficiency at Providing Feedback in a Technology-Based Behavioral Weight Loss Intervention: Longitudinal Analysis. JMIR Form Res. 2021 May 5;5(5):e23974. doi: 10.2196/23974.

Reference Type DERIVED
PMID: 33949954 (View on PubMed)

Manz KC, Waters TM, Clifton HE, Kocak M, Klesges RC, Talcott GW, Krukowski RA. Cost-Effectiveness of a Weight Loss Intervention: An Adaptation of the Look AHEAD Lifestyle Intervention in the US Military. Obesity (Silver Spring). 2020 Jan;28(1):89-96. doi: 10.1002/oby.22681. Epub 2019 Nov 26.

Reference Type DERIVED
PMID: 31773873 (View on PubMed)

Pebley K, Klesges RC, Talcott GW, Kocak M, Krukowski RA. Measurement Equivalence of E-Scale and In-Person Clinic Weights. Obesity (Silver Spring). 2019 Jul;27(7):1107-1114. doi: 10.1002/oby.22512. Epub 2019 Jun 5.

Reference Type DERIVED
PMID: 31168928 (View on PubMed)

Fahey MC, Klesges RC, Kocak M, Wayne Talcott G, Krukowski RA. Changes in the Perceptions of Self-weighing Across Time in a Behavioral Weight Loss Intervention. Obesity (Silver Spring). 2018 Oct;26(10):1566-1575. doi: 10.1002/oby.22275.

Reference Type DERIVED
PMID: 30277031 (View on PubMed)

Krukowski RA, Hare ME, Talcott GW, Gladney LA, Johnson KC, Richey PA, Kocak M, Keller PL, Hryshko-Mullen A, Klesges RC. Dissemination of the Look AHEAD Intensive Lifestyle Intervention in the United States Military: A Randomized Controlled Trial. Obesity (Silver Spring). 2018 Oct;26(10):1558-1565. doi: 10.1002/oby.22293.

Reference Type DERIVED
PMID: 30277030 (View on PubMed)

Fahey MC, Hare ME, Talcott GW, Kocak M, Hryshko-Mullen A, Klesges RC, Krukowski RA. Characteristics Associated With Participation in a Behavioral Weight Loss Randomized Control Trial in the U.S. Military. Mil Med. 2019 Mar 1;184(3-4):e120-e126. doi: 10.1093/milmed/usy199.

Reference Type DERIVED
PMID: 30125001 (View on PubMed)

Krukowski RA, Hare ME, Talcott GW, Johnson KC, Richey PA, Kocak M, Balderas J, Colvin L, Keller PL, Waters TM, Klesges RC. Dissemination of the Look AHEAD intensive lifestyle intervention in the United States Air Force: study rationale, design and methods. Contemp Clin Trials. 2015 Jan;40:232-9. doi: 10.1016/j.cct.2014.12.014. Epub 2014 Dec 26.

Reference Type DERIVED
PMID: 25545025 (View on PubMed)

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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1R01DK097158-01

Identifier Type: NIH

Identifier Source: secondary_id

View Link

1R01DK097158-01

Identifier Type: NIH

Identifier Source: org_study_id

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