Mindfulness-Based Exercise Video in Educating Hispanic/Latino Patients With Colorectal Cancer and Their Caregivers

NCT ID: NCT02057991

Last Updated: 2017-11-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

94 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-01-07

Study Completion Date

2017-11-09

Brief Summary

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This randomized pilot trial studies mindfulness-based program in educating patients with colorectal cancer and their caregivers. A mindfulness-based exercise video may help reduce stress and fatigue in patients with colorectal cancer and their caregivers.

Detailed Description

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PRIMARY OBJECTIVES:

I. To evaluate the effect of a brief educational program on colorectal cancer knowledge acquisition in a 3-arm randomized clinical trial (Control Group: standard of care; Treatment Group 1: cancer education; Treatment Group 2: mindfulness + cancer education) comparing visual/written educational material with and without mindfulness training to the standard of care.

II. To determine the priming effect of a brief mindfulness training on retaining knowledge of colorectal cancer education.

III. To determine the joint effect of colorectal cancer education delivered to both the patient and a caregiver on the overall colorectal cancer knowledge.

SECONDARY OBJECTIVES:

I. To examine the relative changes in psychobiological variables (stress, anxiety, depression, mindfulness, fatigue, life benefit) from pre (T0) to post (T1) intervention in the 3 arms of the clinical trials.

II. To measure changes in salivary cortisol levels as an indicator of acute stress reactivity across 4 time points across a one-hour period (i.e., 0 min, 20 min, 40 min, 60 min) during active chemotherapy (T1).

III. To determine the moderating effect of baseline peripheral levels of inflammation (interleukin-1 \[IL-1\], IL-6, c-reactive protein \[CRP\] and tumor necrosis factor alpha \[TNFa\]) on the trajectory of salivary cortisol reactivity.

OUTLINE: Patients and caregivers are randomized to 1 of 3 groups.

GROUP I: Patients and caregivers receive standard of care.

GROUP II: Patients and caregivers receive a 20-minute self-playing interactive educational video brochure.

GROUP III: Patients and caregivers receive a 20-minute self-playing interactive educational video brochure and watch a 20-minute interactive mindfulness exercise video.

Conditions

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Anxiety Disorder Colon Cancer Depression Fatigue Rectal Cancer

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Group I (standard of care)

Patients and caregivers receive standard of care.

Group Type NO_INTERVENTION

No interventions assigned to this group

Group II (educational video)

Patients and caregivers receive a 20-minute self-playing interactive educational video brochure.

Group Type EXPERIMENTAL

educational intervention

Intervention Type OTHER

Watch an educational video

caregiver-related intervention or procedure

Intervention Type OTHER

Watch mindfulness exercise video and/or educational video

questionnaire administration

Intervention Type OTHER

Ancillary studies

laboratory biomarker analysis

Intervention Type OTHER

Correlative studies

Group III (educational video, mindfulness exercise video)

Patients and caregivers receive a 20-minute self-playing interactive educational video brochure and watch a 20-minute interactive mindfulness exercise video.

Group Type EXPERIMENTAL

educational intervention

Intervention Type OTHER

Watch an educational video

CAM exercise therapy

Intervention Type PROCEDURE

Watch a mindfulness exercise video

caregiver-related intervention or procedure

Intervention Type OTHER

Watch mindfulness exercise video and/or educational video

questionnaire administration

Intervention Type OTHER

Ancillary studies

laboratory biomarker analysis

Intervention Type OTHER

Correlative studies

Interventions

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educational intervention

Watch an educational video

Intervention Type OTHER

CAM exercise therapy

Watch a mindfulness exercise video

Intervention Type PROCEDURE

caregiver-related intervention or procedure

Watch mindfulness exercise video and/or educational video

Intervention Type OTHER

questionnaire administration

Ancillary studies

Intervention Type OTHER

laboratory biomarker analysis

Correlative studies

Intervention Type OTHER

Other Intervention Names

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intervention, educational Exercise Therapy

Eligibility Criteria

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Inclusion Criteria

* Patient diagnosed with colorectal cancer
* Patients with at least one more chemotherapy appointment at the time of enrollment
* if patients have a caregiver, patients should agree to bring a caregiver to one of their hospital visits or have the caregiver schedule a separate study visit
* Ability to understand and the willingness to sign a written informed consent

Exclusion Criteria

* Illiterate participants
* Deaf participants
* Participants that do not read speak or understand either Spanish or English
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Cancer Institute (NCI)

NIH

Sponsor Role collaborator

University of Southern California

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jane Figueiredo

Role: PRINCIPAL_INVESTIGATOR

University of Southern California

Locations

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USC Norris Comprehensive Cancer Center

Los Angeles, California, United States

Site Status

Countries

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United States

Other Identifiers

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NCI-2014-00164

Identifier Type: REGISTRY

Identifier Source: secondary_id

3C-13-6

Identifier Type: OTHER

Identifier Source: secondary_id

R01CA155101

Identifier Type: NIH

Identifier Source: secondary_id

View Link

P30CA014089

Identifier Type: NIH

Identifier Source: secondary_id

View Link

3C-13-6

Identifier Type: -

Identifier Source: org_study_id