Randomized-controlled Trial of Yoga for Ulcerative Colitis

NCT ID: NCT02043600

Last Updated: 2015-09-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

77 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-02-28

Study Completion Date

2015-08-31

Brief Summary

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The aim of this randomized trial is to investigate the effects of a 12-week yoga intervention compared to self-care on quality of life, stress, psychological health, and physiological parameters in 77 patients with ulcerative colitis.

Detailed Description

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Conditions

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Colitis, Ulcerative

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Yoga

Group Type EXPERIMENTAL

Yoga

Intervention Type BEHAVIORAL

12-week Hatha Yoga intervention 90 minutes once a week

Self-care

Group Type ACTIVE_COMPARATOR

Self-care

Intervention Type BEHAVIORAL

Self-care books are provided for self-directed use

Interventions

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Yoga

12-week Hatha Yoga intervention 90 minutes once a week

Intervention Type BEHAVIORAL

Self-care

Self-care books are provided for self-directed use

Intervention Type BEHAVIORAL

Other Intervention Names

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Self-care book

Eligibility Criteria

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Inclusion Criteria

* Ulcerative colitis (clinical, endoscopic and histological diagnosis)
* Disease duration at least 12 months
* Clinical remission for at least 4 weeks and less than 12 months
* CAI \< 5
* IBDQ \< 170
* Physical and mental ability to perform yoga
* No regular practice of yoga or Pilates in the previous 12 months

Exclusion Criteria

* Clinically active disease (CAI \> 4 Rachmilewitz)
* Complete resection of the colon
* Acute, infectious or chronic active ulcerative colitis
* Severe disease precluding yoga practice
* Malignancy with a disease-free survival \< 5 years except curatively treated basalioma of the skin
* Alcohol or drug abuse
* Dementia
* Pregnancy
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Deutsche Morbus Crohn / Colitis ulcerosa Vereinigung DCCV

UNKNOWN

Sponsor Role collaborator

Universität Duisburg-Essen

OTHER

Sponsor Role lead

Responsible Party

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Holger Cramer

Postdoctoral Researcher

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Holger Cramer, PhD

Role: PRINCIPAL_INVESTIGATOR

Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Faculty of Medicine, University of Duisburg-Essen, Essen, Germany

Jost Langhorst, MD

Role: STUDY_DIRECTOR

Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Faculty of Medicine, University of Duisburg-Essen, Essen, Germany

Locations

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Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Faculty of Medicine, University of Duisburg-Essen

Essen, , Germany

Site Status

Countries

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Germany

References

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Tiles-Sar N, Neuser J, de Sordi D, Baltes A, Preiss JC, Moser G, Timmer A. Psychological interventions for treatment of inflammatory bowel disease. Cochrane Database Syst Rev. 2025 Apr 17;4(4):CD006913. doi: 10.1002/14651858.CD006913.pub3.

Reference Type DERIVED
PMID: 40243391 (View on PubMed)

Koch AK, Schols M, Langhorst J, Dobos G, Cramer H. Perceived stress mediates the effect of yoga on quality of life and disease activity in ulcerative colitis. Secondary analysis of a randomized controlled trial. J Psychosom Res. 2020 Mar;130:109917. doi: 10.1016/j.jpsychores.2019.109917. Epub 2019 Dec 31.

Reference Type DERIVED
PMID: 31927346 (View on PubMed)

Cramer H, Schafer M, Schols M, Kocke J, Elsenbruch S, Lauche R, Engler H, Dobos G, Langhorst J. Randomised clinical trial: yoga vs written self-care advice for ulcerative colitis. Aliment Pharmacol Ther. 2017 Jun;45(11):1379-1389. doi: 10.1111/apt.14062. Epub 2017 Apr 5.

Reference Type DERIVED
PMID: 28378342 (View on PubMed)

Other Identifiers

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13-5560-BO

Identifier Type: -

Identifier Source: org_study_id

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