Trial Outcomes & Findings for Comparison of Treatment for Hoarding Disorder (NCT NCT02040805)
NCT ID: NCT02040805
Last Updated: 2020-02-11
Results Overview
This is a 23-item self-report questionnaire that measures hoarding symptoms and their impact, including problems with acquisition, clutter, and difficulty discarding, as well as distress and impairment/interference. The SI-R is scored on a scale of 0-92. Higher scores indicate more severe hoarding, and scores of 42 and over are considered clinically significant hoarding. Although subscale scores can be calculated, this study uses total scores as the primary outcome.
Recruitment status
COMPLETED
Study phase
NA
Target enrollment
323 participants
Primary outcome timeframe
Administered at screening before start of treatment groups and after last treatment group (20 weeks later).
Results posted on
2020-02-11
Participant Flow
Recruitment occurred during April 2014 through February 2016. Participants were individuals with Hoarding Disorder recruited primarily through the Mental Health Association - San Francisco and flyers in the bay area (e.g. community center boards, coffee shops, laundry mats, libraries).
Participant milestones
| Measure |
Group Cognitive-Behavioral Therapy
Sixteen sessions of group therapy facilitated by a psychologist.
Group Cognitive Behavioral Therapy: Group therapy over approximately 20 weeks, based on a structured manual adapted from the individual CBT workbook for hoarding by Steketee and Frost (2006). Each session will be 2 hours in length and consists of weekly check-ins, psychoeducation about hoarding, developing understanding and awareness of one's hoarding symptoms and patterns, behavior modification, cognitive restructuring, goal-setting, motivational enhancement, in vivo and imaginal exposure for discarding and acquisition, executive skills training (organization, sorting, planning, decision-making, problem-solving, etc.), guidelines on establishing "clutter buddies", and relapse prevention. Groups will be led by clinical postdoctoral psychology fellows in the Department of Psychiatry at UCSF.
|
Peer Facilitated Support Group
Fifteen sessions of peer-facilitated group support.
Peer Facilitated Support Group: Fifteen sessions of peer facilitated, group support, over the course of 20 weeks, based on a structured manualized approach (Buried in Treasures: Help for Compulsive Acquiring, Saving, and Hoarding). Each session will be 2 hours in length. In this model, two trained peers, usually, but not necessarily, with personal lived experience of hoarding, will guide the group chapter by chapter through the Buried in Treasures manual.
|
|---|---|---|
|
Overall Study
STARTED
|
160
|
163
|
|
Overall Study
COMPLETED
|
118
|
113
|
|
Overall Study
NOT COMPLETED
|
42
|
50
|
Reasons for withdrawal
| Measure |
Group Cognitive-Behavioral Therapy
Sixteen sessions of group therapy facilitated by a psychologist.
Group Cognitive Behavioral Therapy: Group therapy over approximately 20 weeks, based on a structured manual adapted from the individual CBT workbook for hoarding by Steketee and Frost (2006). Each session will be 2 hours in length and consists of weekly check-ins, psychoeducation about hoarding, developing understanding and awareness of one's hoarding symptoms and patterns, behavior modification, cognitive restructuring, goal-setting, motivational enhancement, in vivo and imaginal exposure for discarding and acquisition, executive skills training (organization, sorting, planning, decision-making, problem-solving, etc.), guidelines on establishing "clutter buddies", and relapse prevention. Groups will be led by clinical postdoctoral psychology fellows in the Department of Psychiatry at UCSF.
|
Peer Facilitated Support Group
Fifteen sessions of peer-facilitated group support.
Peer Facilitated Support Group: Fifteen sessions of peer facilitated, group support, over the course of 20 weeks, based on a structured manualized approach (Buried in Treasures: Help for Compulsive Acquiring, Saving, and Hoarding). Each session will be 2 hours in length. In this model, two trained peers, usually, but not necessarily, with personal lived experience of hoarding, will guide the group chapter by chapter through the Buried in Treasures manual.
|
|---|---|---|
|
Overall Study
Lost to Follow-up
|
14
|
9
|
|
Overall Study
Withdrawal by Subject
|
28
|
41
|
Baseline Characteristics
322 of the 323 randomized participants provided race/ethnicity information.
Baseline characteristics by cohort
| Measure |
Group Cognitive-Behavioral Therapy
n=160 Participants
Sixteen sessions of group therapy facilitated by a psychologist.
Group Cognitive Behavioral Therapy: Group therapy over approximately 20 weeks, based on a structured manual adapted from the individual CBT workbook for hoarding by Steketee and Frost (2006). Each session will be 2 hours in length and consists of weekly check-ins, psychoeducation about hoarding, developing understanding and awareness of one's hoarding symptoms and patterns, behavior modification, cognitive restructuring, goal-setting, motivational enhancement, in vivo and imaginal exposure for discarding and acquisition, executive skills training (organization, sorting, planning, decision-making, problem-solving, etc.), guidelines on establishing "clutter buddies", and relapse prevention. Groups will be led by clinical postdoctoral psychology fellows in the Department of Psychiatry at UCSF.
|
Peer Facilitated Support Group
n=163 Participants
Fifteen sessions of peer-facilitated group support.
Peer Facilitated Support Group: Fifteen sessions of peer facilitated, group support, over the course of 20 weeks, based on a structured manualized approach (Buried in Treasures: Help for Compulsive Acquiring, Saving, and Hoarding). Each session will be 2 hours in length. In this model, two trained peers, usually, but not necessarily, with personal lived experience of hoarding, will guide the group chapter by chapter through the Buried in Treasures manual.
|
Total
n=323 Participants
Total of all reporting groups
|
|---|---|---|---|
|
Age, Continuous
|
59.0 years
STANDARD_DEVIATION 10.9 • n=160 Participants
|
58.9 years
STANDARD_DEVIATION 10.6 • n=163 Participants
|
59.0 years
STANDARD_DEVIATION 10.7 • n=323 Participants
|
|
Sex: Female, Male
Female
|
117 Participants
n=160 Participants
|
124 Participants
n=163 Participants
|
241 Participants
n=323 Participants
|
|
Sex: Female, Male
Male
|
43 Participants
n=160 Participants
|
39 Participants
n=163 Participants
|
82 Participants
n=323 Participants
|
|
Race/Ethnicity, Customized
Race/Ethnicity Characteristics · American Indian/Alaskan Native
|
0 Participants
n=160 Participants • 322 of the 323 randomized participants provided race/ethnicity information.
|
1 Participants
n=162 Participants • 322 of the 323 randomized participants provided race/ethnicity information.
|
1 Participants
n=322 Participants • 322 of the 323 randomized participants provided race/ethnicity information.
|
|
Race/Ethnicity, Customized
Race/Ethnicity Characteristics · Asian
|
16 Participants
n=160 Participants • 322 of the 323 randomized participants provided race/ethnicity information.
|
17 Participants
n=162 Participants • 322 of the 323 randomized participants provided race/ethnicity information.
|
33 Participants
n=322 Participants • 322 of the 323 randomized participants provided race/ethnicity information.
|
|
Race/Ethnicity, Customized
Race/Ethnicity Characteristics · Black/African American
|
17 Participants
n=160 Participants • 322 of the 323 randomized participants provided race/ethnicity information.
|
6 Participants
n=162 Participants • 322 of the 323 randomized participants provided race/ethnicity information.
|
23 Participants
n=322 Participants • 322 of the 323 randomized participants provided race/ethnicity information.
|
|
Race/Ethnicity, Customized
Race/Ethnicity Characteristics · Hispanic
|
9 Participants
n=160 Participants • 322 of the 323 randomized participants provided race/ethnicity information.
|
8 Participants
n=162 Participants • 322 of the 323 randomized participants provided race/ethnicity information.
|
17 Participants
n=322 Participants • 322 of the 323 randomized participants provided race/ethnicity information.
|
|
Race/Ethnicity, Customized
Race/Ethnicity Characteristics · Native Hawaiian/Other Pacific Islander
|
2 Participants
n=160 Participants • 322 of the 323 randomized participants provided race/ethnicity information.
|
1 Participants
n=162 Participants • 322 of the 323 randomized participants provided race/ethnicity information.
|
3 Participants
n=322 Participants • 322 of the 323 randomized participants provided race/ethnicity information.
|
|
Race/Ethnicity, Customized
Race/Ethnicity Characteristics · Other or Multiracial
|
23 Participants
n=160 Participants • 322 of the 323 randomized participants provided race/ethnicity information.
|
23 Participants
n=162 Participants • 322 of the 323 randomized participants provided race/ethnicity information.
|
46 Participants
n=322 Participants • 322 of the 323 randomized participants provided race/ethnicity information.
|
|
Race/Ethnicity, Customized
Race/Ethnicity Characteristics · White
|
89 Participants
n=160 Participants • 322 of the 323 randomized participants provided race/ethnicity information.
|
101 Participants
n=162 Participants • 322 of the 323 randomized participants provided race/ethnicity information.
|
190 Participants
n=322 Participants • 322 of the 323 randomized participants provided race/ethnicity information.
|
|
Race/Ethnicity, Customized
Race/Ethnicity Characteristics · Prefer not to answer
|
4 Participants
n=160 Participants • 322 of the 323 randomized participants provided race/ethnicity information.
|
5 Participants
n=162 Participants • 322 of the 323 randomized participants provided race/ethnicity information.
|
9 Participants
n=322 Participants • 322 of the 323 randomized participants provided race/ethnicity information.
|
PRIMARY outcome
Timeframe: Administered at screening before start of treatment groups and after last treatment group (20 weeks later).Population: All randomized participants who were not lost to follow-up.
This is a 23-item self-report questionnaire that measures hoarding symptoms and their impact, including problems with acquisition, clutter, and difficulty discarding, as well as distress and impairment/interference. The SI-R is scored on a scale of 0-92. Higher scores indicate more severe hoarding, and scores of 42 and over are considered clinically significant hoarding. Although subscale scores can be calculated, this study uses total scores as the primary outcome.
Outcome measures
| Measure |
Group Cognitive-Behavioral Therapy
n=160 Participants
Sixteen sessions of group therapy facilitated by a psychologist.
Group Cognitive Behavioral Therapy: Group therapy over approximately 20 weeks, based on a structured manual adapted from the individual CBT workbook for hoarding by Steketee and Frost (2006). Each session will be 2 hours in length and consists of weekly check-ins, psychoeducation about hoarding, developing understanding and awareness of one's hoarding symptoms and patterns, behavior modification, cognitive restructuring, goal-setting, motivational enhancement, in vivo and imaginal exposure for discarding and acquisition, executive skills training (organization, sorting, planning, decision-making, problem-solving, etc.), guidelines on establishing "clutter buddies", and relapse prevention. Groups will be led by clinical postdoctoral psychology fellows in the Department of Psychiatry at UCSF.
|
Peer Facilitated Support Group
n=163 Participants
Fifteen sessions of peer-facilitated group support.
Peer Facilitated Support Group: Fifteen sessions of peer facilitated, group support, over the course of 20 weeks, based on a structured manualized approach (Buried in Treasures: Help for Compulsive Acquiring, Saving, and Hoarding). Each session will be 2 hours in length. In this model, two trained peers, usually, but not necessarily, with personal lived experience of hoarding, will guide the group chapter by chapter through the Buried in Treasures manual.
|
|---|---|---|
|
Saving Inventory-Revised (SI-R)
Baseline
|
64.5 units on a scale
Standard Deviation 11.7
|
66.4 units on a scale
Standard Deviation 11.6
|
|
Saving Inventory-Revised (SI-R)
End of Treatment: 20 weeks later
|
45.9 units on a scale
Standard Deviation 15.0
|
47.8 units on a scale
Standard Deviation 14.2
|
SECONDARY outcome
Timeframe: Administered at baseline and after last treatment group (20 weeks later).Population: All randomized participants who were not lost to follow-up.
The ADL-H is a 15-item self-report questionnaire that measures hoarding specific difficulties or problems that may impact daily functioning. It includes questions on activities affected by clutter or hoarding, problems in the home, and safety issues. For this study, the score on each ADL-H item was summed to create a total score ranging from 0 to 75. Higher scores indicate more severe functional impairment due to hoarding.
Outcome measures
| Measure |
Group Cognitive-Behavioral Therapy
n=160 Participants
Sixteen sessions of group therapy facilitated by a psychologist.
Group Cognitive Behavioral Therapy: Group therapy over approximately 20 weeks, based on a structured manual adapted from the individual CBT workbook for hoarding by Steketee and Frost (2006). Each session will be 2 hours in length and consists of weekly check-ins, psychoeducation about hoarding, developing understanding and awareness of one's hoarding symptoms and patterns, behavior modification, cognitive restructuring, goal-setting, motivational enhancement, in vivo and imaginal exposure for discarding and acquisition, executive skills training (organization, sorting, planning, decision-making, problem-solving, etc.), guidelines on establishing "clutter buddies", and relapse prevention. Groups will be led by clinical postdoctoral psychology fellows in the Department of Psychiatry at UCSF.
|
Peer Facilitated Support Group
n=163 Participants
Fifteen sessions of peer-facilitated group support.
Peer Facilitated Support Group: Fifteen sessions of peer facilitated, group support, over the course of 20 weeks, based on a structured manualized approach (Buried in Treasures: Help for Compulsive Acquiring, Saving, and Hoarding). Each session will be 2 hours in length. In this model, two trained peers, usually, but not necessarily, with personal lived experience of hoarding, will guide the group chapter by chapter through the Buried in Treasures manual.
|
|---|---|---|
|
Activities of Daily Living Scale, Hoarding (ADL-H)
Baseline
|
29.9 units on a scale
Standard Deviation 9.5
|
32.0 units on a scale
Standard Deviation 11.2
|
|
Activities of Daily Living Scale, Hoarding (ADL-H)
End of Treatment: 20 weeks later
|
25.5 units on a scale
Standard Deviation 10.1
|
26.1 units on a scale
Standard Deviation 8.7
|
POST_HOC outcome
Timeframe: The post-hoc longitudinal data were collected at varying time points, but at least three months after the treatment ended. The range was 3 months to 25 months, with a mean of 14 months after treatment end.Population: All randomized participants who were not lost to follow-up.
This is a 23-item self-report questionnaire that measures hoarding symptoms and their impact, including problems with acquisition, clutter, and difficulty discarding, as well as distress and impairment/interference. Using the SI-R, we obtained longitudinal follow-up data (defined as a second post-treatment assessment of hoarding symptom severity at least three months following completion of treatment). The total SI-R score was used, which ranges from 0-92, higher scores indicating more severe hoarding.
Outcome measures
| Measure |
Group Cognitive-Behavioral Therapy
n=101 Participants
Sixteen sessions of group therapy facilitated by a psychologist.
Group Cognitive Behavioral Therapy: Group therapy over approximately 20 weeks, based on a structured manual adapted from the individual CBT workbook for hoarding by Steketee and Frost (2006). Each session will be 2 hours in length and consists of weekly check-ins, psychoeducation about hoarding, developing understanding and awareness of one's hoarding symptoms and patterns, behavior modification, cognitive restructuring, goal-setting, motivational enhancement, in vivo and imaginal exposure for discarding and acquisition, executive skills training (organization, sorting, planning, decision-making, problem-solving, etc.), guidelines on establishing "clutter buddies", and relapse prevention. Groups will be led by clinical postdoctoral psychology fellows in the Department of Psychiatry at UCSF.
|
Peer Facilitated Support Group
n=82 Participants
Fifteen sessions of peer-facilitated group support.
Peer Facilitated Support Group: Fifteen sessions of peer facilitated, group support, over the course of 20 weeks, based on a structured manualized approach (Buried in Treasures: Help for Compulsive Acquiring, Saving, and Hoarding). Each session will be 2 hours in length. In this model, two trained peers, usually, but not necessarily, with personal lived experience of hoarding, will guide the group chapter by chapter through the Buried in Treasures manual.
|
|---|---|---|
|
Longitudinal Follow-Up: Saving Inventory-Revised (SI-R)
|
48.2 units on a scale
Standard Deviation 14.9
|
47.9 units on a scale
Standard Deviation 13.9
|
POST_HOC outcome
Timeframe: Post-hoc longitudinal analyses were conducted at three or more months' following the end of treatment. The range was 3-25 months, and the mean time to longitudinal follow up was 14 months.Population: All randomized participants who were not lost to follow-up.
The ADL-H is a 15-item self-report questionnaire that measures hoarding specific difficulties or problems that may impact daily functioning. It includes questions on activities affected by clutter or hoarding, problems in the home, and safety issues. Using the ADL-H, we obtained longitudinal follow-up data (defined as a second post-treatment assessment of hoarding specific difficulties or problems that may impact daily functioning at least three months following completion of treatment). For this study, a total score using the sum of all of the items was created, ranging from 0 to a total possible of 75. Higher scores indicate more severe impairment due to hoarding.
Outcome measures
| Measure |
Group Cognitive-Behavioral Therapy
n=98 Participants
Sixteen sessions of group therapy facilitated by a psychologist.
Group Cognitive Behavioral Therapy: Group therapy over approximately 20 weeks, based on a structured manual adapted from the individual CBT workbook for hoarding by Steketee and Frost (2006). Each session will be 2 hours in length and consists of weekly check-ins, psychoeducation about hoarding, developing understanding and awareness of one's hoarding symptoms and patterns, behavior modification, cognitive restructuring, goal-setting, motivational enhancement, in vivo and imaginal exposure for discarding and acquisition, executive skills training (organization, sorting, planning, decision-making, problem-solving, etc.), guidelines on establishing "clutter buddies", and relapse prevention. Groups will be led by clinical postdoctoral psychology fellows in the Department of Psychiatry at UCSF.
|
Peer Facilitated Support Group
n=80 Participants
Fifteen sessions of peer-facilitated group support.
Peer Facilitated Support Group: Fifteen sessions of peer facilitated, group support, over the course of 20 weeks, based on a structured manualized approach (Buried in Treasures: Help for Compulsive Acquiring, Saving, and Hoarding). Each session will be 2 hours in length. In this model, two trained peers, usually, but not necessarily, with personal lived experience of hoarding, will guide the group chapter by chapter through the Buried in Treasures manual.
|
|---|---|---|
|
Longitudinal Follow-Up: Activities of Daily Living Scale, Hoarding (ADL-H)
|
27.6 units on a scale
Standard Deviation 11.6
|
27.8 units on a scale
Standard Deviation 9.7
|
Adverse Events
Group Cognitive-Behavioral Therapy
Serious events: 0 serious events
Other events: 1 other events
Deaths: 0 deaths
Peer Facilitated Support Group
Serious events: 0 serious events
Other events: 2 other events
Deaths: 0 deaths
Serious adverse events
Adverse event data not reported
Other adverse events
| Measure |
Group Cognitive-Behavioral Therapy
n=160 participants at risk
Sixteen sessions of group therapy facilitated by a psychologist.
Group Cognitive Behavioral Therapy: Group therapy over approximately 20 weeks, based on a structured manual adapted from the individual CBT workbook for hoarding by Steketee and Frost (2006). Each session will be 2 hours in length and consists of weekly check-ins, psychoeducation about hoarding, developing understanding and awareness of one's hoarding symptoms and patterns, behavior modification, cognitive restructuring, goal-setting, motivational enhancement, in vivo and imaginal exposure for discarding and acquisition, executive skills training (organization, sorting, planning, decision-making, problem-solving, etc.), guidelines on establishing "clutter buddies", and relapse prevention. Groups will be led by clinical postdoctoral psychology fellows in the Department of Psychiatry at UCSF.
|
Peer Facilitated Support Group
n=163 participants at risk
Fifteen sessions of peer-facilitated group support.
Peer Facilitated Support Group: Fifteen sessions of peer facilitated, group support, over the course of 20 weeks, based on a structured manualized approach (Buried in Treasures: Help for Compulsive Acquiring, Saving, and Hoarding). Each session will be 2 hours in length. In this model, two trained peers, usually, but not necessarily, with personal lived experience of hoarding, will guide the group chapter by chapter through the Buried in Treasures manual.
|
|---|---|---|
|
Psychiatric disorders
Voluntary hospitalization due to "alcohol detox" "possible suicidality"
|
0.62%
1/160
|
0.00%
0/163
|
|
Psychiatric disorders
Suicidality
|
0.00%
0/160
|
0.61%
1/163
|
|
Social circumstances
Participant Fell
|
0.00%
0/160
|
0.61%
1/163
|
Additional Information
Dr. Kevin L. Delucchi
University of California, San Francisco
Phone: 415-476-4180
Email: [email protected]
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place