The Effect of Repeated Lifestyle Intervention on Weight Loss Maintenance

NCT ID: NCT02040753

Last Updated: 2016-02-01

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 2120 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2014-02-28
• Study Completion Date: 2016-01-31

Brief Summary

In Denmark and the western world, there is an increasing prevalence of obesity probably due to a combination of inadequate daily physical activity and a high energy intake. One approach to achieve weight loss and change life style is to participate in an intensive supervised prolonged life style modification course. The immediate effect is often positive, but over time the overall effect is limited as the majority will not maintain weight loss and a changed life style.

In this study we will analyse the results of the intensive lifestyle intervention as it has been practised at Ubberup Folk High School over the last 13 years. As some people have several stays at Ubberup Folk High School we want to we have a special interest in the effect of repeated lifestyle intervention.

Research question:

What is the effect of several lifestyle interventions on weight loss maintenance?

The study design is retrospective and descriptive and will be based on a lifestyle intervention, as it has practiced in a real life setting at Ubberup folk high school.

Conditions

Obesity; Overweight

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: RETROSPECTIVE

Study Groups

Intensive Lifestyle Intervention

Former participants of intensive lifestyle intervention at Ubberup Folk High School.

Intensive Lifestyle Intervention

Intervention Type: BEHAVIORAL

Intensive Lifestyle intervention at Ubberup Folk High School for 10-14 weeks. Daily exercise for 1-3hrs. Calorie restriction. Education within Nutrition, exercise and healthy living in general.

Interventions

Intensive Lifestyle Intervention

Intensive Lifestyle intervention at Ubberup Folk High School for 10-14 weeks. Daily exercise for 1-3hrs. Calorie restriction. Education within Nutrition, exercise and healthy living in general.

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• Former participants of the intensive lifestyle intervention at Ubberup Folk High School.

Exclusion Criteria

• Gastric bypass surgery or banding

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 65 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Ubberup Folk High School

OTHER

Sponsor Role: collaborator

University of Copenhagen

OTHER

Sponsor Role: lead

Responsible Party

Jørn Wulff Helge

Associate Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Jørn W Helge, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Copenhagen, Department of Biomedical Sciences

Locations

University of Copenhagen, Department of Biomedical Sciences

Copenhagen, , Denmark

Countries

Denmark

References

Karlsen TI, Sohagen M, Hjelmesaeth J. Predictors of weight loss after an intensive lifestyle intervention program in obese patients: a 1-year prospective cohort study. Health Qual Life Outcomes. 2013 Oct 3;11:165. doi: 10.1186/1477-7525-11-165.

Reference Type: BACKGROUND

PMID: 24090083 (View on PubMed)

McCormack SE, McCarthy MA, Harrington SG, Farilla L, Hrovat MI, Systrom DM, Thomas BJ, Torriani M, McInnis K, Grinspoon SK, Fleischman A. Effects of exercise and lifestyle modification on fitness, insulin resistance, skeletal muscle oxidative phosphorylation and intramyocellular lipid content in obese children and adolescents. Pediatr Obes. 2014 Aug;9(4):281-91. doi: 10.1111/j.2047-6310.2013.00180.x. Epub 2013 Jun 25.

Reference Type: BACKGROUND

PMID: 23801526 (View on PubMed)

Danielsen KK, Svendsen M, Maehlum S, Sundgot-Borgen J. Changes in body composition, cardiovascular disease risk factors, and eating behavior after an intensive lifestyle intervention with high volume of physical activity in severely obese subjects: a prospective clinical controlled trial. J Obes. 2013;2013:325464. doi: 10.1155/2013/325464. Epub 2013 Apr 22.

Reference Type: BACKGROUND

PMID: 23710347 (View on PubMed)

Bruun JM, Helge JW, Richelsen B, Stallknecht B. Diet and exercise reduce low-grade inflammation and macrophage infiltration in adipose tissue but not in skeletal muscle in severely obese subjects. Am J Physiol Endocrinol Metab. 2006 May;290(5):E961-7. doi: 10.1152/ajpendo.00506.2005. Epub 2005 Dec 13.

Reference Type: BACKGROUND

PMID: 16352667 (View on PubMed)

Pedersen JO, Zimmermann E, Stallknecht BM, Bruun JM, Kroustrup JP, Larsen JF, Helge JW. [Lifestyle intervention in the treatment of severe obesity]. Ugeskr Laeger. 2006 Jan 9;168(2):167-72. Danish.

Reference Type: BACKGROUND

PMID: 16403343 (View on PubMed)

Bruun JM, Stallknecht B, Helge JW, Richelsen B. Interleukin-18 in plasma and adipose tissue: effects of obesity, insulin resistance, and weight loss. Eur J Endocrinol. 2007 Oct;157(4):465-71. doi: 10.1530/EJE-07-0206.

Reference Type: BACKGROUND

PMID: 17893261 (View on PubMed)

Christiansen T, Bruun JM, Madsen EL, Richelsen B. Weight loss maintenance in severely obese adults after an intensive lifestyle intervention: 2- to 4-year follow-up. Obesity (Silver Spring). 2007 Feb;15(2):413-20. doi: 10.1038/oby.2007.530.

Reference Type: BACKGROUND

PMID: 17299115 (View on PubMed)

Dandanell S, Skovborg C, Praest CB, Kristensen KB, Nielsen MG, Lionett S, Jorgensen SD, Vigelso A, Dela F, Helge JW. Maintaining a clinical weight loss after intensive lifestyle intervention is the key to cardiometabolic health. Obes Res Clin Pract. 2017 Jul-Aug;11(4):489-498. doi: 10.1016/j.orcp.2016.09.009. Epub 2016 Oct 5.

Reference Type: DERIVED

PMID: 27720417 (View on PubMed)

Other Identifiers

UBBERUP1

Identifier Type: -

Identifier Source: org_study_id