Investigating the Role of EN in NTIS Among Fistula Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-01-31

Study Completion Date

2014-04-30

Brief Summary

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The purpose of this study is to investigate whether enteral nutrition are effective in the treatment of nonthyroidal illness syndrome among fistula patients.

Detailed Description

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Nonthyroidal illness syndrome (NTIS) is a common alterations in thyroid function observed in about 70% of hospitalized patients, with or without acute systemic illnesses. Mechanisms in the pathogenesis of NTIS are not yet well understood. Our previous study demonstrated that NTIS occurred frequently with a prevalence of 57.5% in gastrointestinal fistulas patients. In recent study, it has been shown that early enteral nutrition decreases the duration of hospitalization and mortality in the burn population, indicating a potential role of enteral nutrition in NTIS.In addition, the management of fistula patients requires bundle therapy including Nutrition therapy, especially enteral nutrition.The purpose of this study is to investigate whether enteral nutrition are effective in the treatment of nonthyroidal illness syndrome among fistula patients.

Conditions

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Gastrointestinal Fistula

Keywords

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gastrointestinal fistula enteral nutrition thyroid function

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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gastrointestinal fistula

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Clinical diagnosis of gastrointestinal fistula
* Clinical diagnosis of nonthyroidal illness syndrome
* Using enteral nutrition for fistula management

Exclusion Criteria

* patients who were prescribed drug which may affect thyroid function before or in our study
* patients who were diagnosed as primary thyroid disease

Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Jianan Ren

VIce-president of General Surgery, Jinling Hospital, Professor of Medical School of Nanjing University

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Department of General Surgery, Jinling Hospital

Nanjing, Jiangsu, China

Site Status

Countries

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China

Other Identifiers

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81270478

Identifier Type: OTHER

Identifier Source: secondary_id

NTIS-EN-1

Identifier Type: -

Identifier Source: org_study_id