Study Results
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View full resultsBasic Information
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TERMINATED
PHASE4
13 participants
INTERVENTIONAL
2012-09-30
2016-07-08
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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Phenylephrine
Phenylephrine for maintaining blood pressure within 10 % of baseline
Phenylephrine
Ephedrine
Ephedrine for maintaining blood pressure within 10 % of baseline
Ephedrine
Interventions
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Phenylephrine
Ephedrine
Eligibility Criteria
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Inclusion Criteria
* Age ≥18 yrs
* Pre-eclampsia (mild, or severe)
* Non-laboring women
* CD under spinal anesthesia
Exclusion Criteria
* Allergy to phenylephrine or ephedrine, or any other standardized medication
* Severe Cardiac disease in pregnancy with marked functional limitations (NYHA Class III and IV)
* Patients on Monoamine Oxidase Inhibitors or Tricyclic Antidepressants
* History of recent amphetamine or cocaine use.
* Subject enrollment in another study involving a study medication within 30 days of CD
* Any other physical or psychiatric condition which may impair their ability to cooperate with study data collection
18 Years
50 Years
FEMALE
No
Sponsors
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Duke University
OTHER
Responsible Party
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Principal Investigators
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Ashraf S Habib, MD
Role: PRINCIPAL_INVESTIGATOR
Duke University
Locations
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Duke University Medical Center
Durham, North Carolina, United States
Countries
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Other Identifiers
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Pro00032812
Identifier Type: -
Identifier Source: org_study_id
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