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Trial Outcomes & Findings for Maintaining Cognitive Health in Aging Veterans (NCT NCT02023944)

NCT ID: NCT02023944

Last Updated: 2019-05-31

Results Overview

Measures laypersons' knowledge of memory changes in adulthood for research or educational purposes using true/false/"don't know" questions, with half of the questions pertaining to normal memory aging and the other half covering pathological memory deficits due to non-normative factors, such as dementia. Test-retest reliability and convergent and discriminant validity were established at adequate levels. Minimum value is 0, maximum value is 28, higher scores indicate better knowledge of memory aging.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

50 participants

Primary outcome timeframe

Within 1 week of start of program

Results posted on

2019-05-31

Participant Flow

One participant was recruited, assigned to the control group, and then dropped out before the baseline due to dissatisfaction with group assignment.

Participant milestones

Participant milestones
Measure
Intervention
12-week course on aging Memory and Aging Course: This is a 12-week course that will provide participants with an understanding of what normal and pathological aging processes look like. It will also provide participants with methods to maintain healthy lifestyles as they continue to grow older.
Control, No Intervention
No Intervention; considered "treatment as usual"
Overall Study
STARTED
25
25
Overall Study
COMPLETED
25
24
Overall Study
NOT COMPLETED
0
1

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Maintaining Cognitive Health in Aging Veterans

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Intervention
n=25 Participants
12-week course on aging Memory and Aging Course: This is a 12-week course that will provide participants with an understanding of what normal and pathological aging processes look like. It will also provide participants with methods to maintain healthy lifestyles as they continue to grow older.
Control, No Intervention
n=24 Participants
No Intervention, considered "treatment as usual"
Total
n=49 Participants
Total of all reporting groups
Age, Categorical
<=18 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
3 Participants
n=5 Participants
2 Participants
n=7 Participants
5 Participants
n=5 Participants
Age, Categorical
>=65 years
22 Participants
n=5 Participants
22 Participants
n=7 Participants
44 Participants
n=5 Participants
Age, Continuous
73.6 years
n=5 Participants
73.6 years
n=7 Participants
73.6 years
n=5 Participants
Sex: Female, Male
Female
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Sex: Female, Male
Male
25 Participants
n=5 Participants
24 Participants
n=7 Participants
49 Participants
n=5 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Race (NIH/OMB)
Asian
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Race (NIH/OMB)
Black or African American
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Race (NIH/OMB)
White
25 Participants
n=5 Participants
24 Participants
n=7 Participants
49 Participants
n=5 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Region of Enrollment
United States
25 Participants
n=5 Participants
24 Participants
n=7 Participants
49 Participants
n=5 Participants
Memory Controllability Inventory
65.2 units on a scale
STANDARD_DEVIATION 9.8 • n=5 Participants
57.4 units on a scale
STANDARD_DEVIATION 10.4 • n=7 Participants
60.7 units on a scale
STANDARD_DEVIATION 7.2 • n=5 Participants

PRIMARY outcome

Timeframe: Within 1 week of start of program

Measures laypersons' knowledge of memory changes in adulthood for research or educational purposes using true/false/"don't know" questions, with half of the questions pertaining to normal memory aging and the other half covering pathological memory deficits due to non-normative factors, such as dementia. Test-retest reliability and convergent and discriminant validity were established at adequate levels. Minimum value is 0, maximum value is 28, higher scores indicate better knowledge of memory aging.

Outcome measures

Outcome measures
Measure
Intervention
n=25 Participants
12-week course on aging Memory and Aging Course: This is a 12-week course that will provide participants with an understanding of what normal and pathological aging processes look like. It will also provide participants with methods to maintain healthy lifestyles as they continue to grow older.
Control, No Intervention
n=24 Participants
No Intervention, considered "treatment as usual"
Knowledge of Memory Aging Questionnaire-Revised
19.8 units on a scale
Standard Deviation 2.7
19.5 units on a scale
Standard Deviation 3.6

SECONDARY outcome

Timeframe: Within 1 week of start of program

The MMQ is a measure constructed to reflect aspects of memory that are potentially amenable to clinical intervention. The scale consists of three subscales - memory contentment, memory ability, and memory strategy use. Higher scores indicate, respectively, greater contentment, ability, and strategy use. Minimum 0, maximum 80

Outcome measures

Outcome measures
Measure
Intervention
n=25 Participants
12-week course on aging Memory and Aging Course: This is a 12-week course that will provide participants with an understanding of what normal and pathological aging processes look like. It will also provide participants with methods to maintain healthy lifestyles as they continue to grow older.
Control, No Intervention
n=24 Participants
No Intervention, considered "treatment as usual"
Multifactorial Memory Questionnaire (MMQ)
Memory Contentment
46.7 units on a scale
Standard Deviation 12.8
38.7 units on a scale
Standard Deviation 15.2
Multifactorial Memory Questionnaire (MMQ)
Memory Ability
52.6 units on a scale
Standard Deviation 8.4
50.5 units on a scale
Standard Deviation 11.4
Multifactorial Memory Questionnaire (MMQ)
Memory Strategy
41.0 units on a scale
Standard Deviation 8.7
36.5 units on a scale
Standard Deviation 7.1

Adverse Events

Intervention

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Control, No Intervention

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Maureen K. O'Connor

Bedford Veterans Hospital

Phone: 781-687-2830

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place