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Single Application of Desensitizing Pastes as Dentin Sensitivity Treatment

NCT ID: NCT02018783

Last Updated: 2013-12-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

138 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-04-30

Study Completion Date

2013-08-31

Brief Summary

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The aim of this study was to evaluate the efficacy of three desensitizing toothpastes for immediate and intermediate-term relief of CDH, when compared with a control toothpaste. One hundred and thirty-eight hypersensitive teeth were diagnosed and randomized into four groups according to the therapeutic agent of each desensitizing cream tested: 1) strontium acetate and calcium carbonate, 2) calcium carbonate and arginine 8%, 3) calcium phosphate nanoparticles and 4) a control toothpaste. The desensitizing creams were applied according to the manufacturer's instructions. Cervical dentin hypersensitivity was assessed at baseline, immediately, 24 hours and 30 days after the treatment. Cold and evaporative tests were used to assess the sensitivity level.

Detailed Description

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Conditions

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Dentine Hypersensitivity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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Sensodyne

Digital application for 60 seconds.

Group Type EXPERIMENTAL

Sensodyne

Intervention Type PROCEDURE

Digital application for 60 seconds.

Colgate

Slow-speed handpiece with a Robson brush for 3 seconds by repeating the procedure

Group Type EXPERIMENTAL

Colgate

Intervention Type PROCEDURE

Slow-speed handpiece with a Robson brush for 3 seconds by repeating the procedure

Nano P

Slow-speed handpiece with a Robson brush for 10 seconds

Group Type EXPERIMENTAL

Nano P

Intervention Type PROCEDURE

Slow-speed handpiece with a Robson brush for 10 seconds

Cocorico

Digital application for 60 seconds

Group Type PLACEBO_COMPARATOR

Cocorico

Intervention Type PROCEDURE

Digital application for 60 seconds

Interventions

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Colgate

Slow-speed handpiece with a Robson brush for 3 seconds by repeating the procedure

Intervention Type PROCEDURE

Sensodyne

Digital application for 60 seconds.

Intervention Type PROCEDURE

Nano P

Slow-speed handpiece with a Robson brush for 10 seconds

Intervention Type PROCEDURE

Cocorico

Digital application for 60 seconds

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* subjects 18 years or older
* in good general and oral health; have complaint of CDH in teeth distributed in all 4 quadrants
* not making use of desensitizing agents
* not having undergone periodontal treatment over the past 3 months
* respond to evaporative stimulus with a score ≥ 1.5 cm on VAS

Exclusion Criteria

* patients who presented restorations and caries near the exposed dentin of the hypersensitive teeth
* who made frequent use of painkillers, anti-inflammatory and antidepressants drugs
Minimum Eligible Age

22 Years

Maximum Eligible Age

48 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Federal University of São Paulo

OTHER

Sponsor Role lead

Responsible Party

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Olga Flecha

PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Olga D Flecha, PhD

Role: PRINCIPAL_INVESTIGATOR

Federal University of São Paulo

Locations

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Periodontics Clinic, Department of Dentistry

Diamantina, Minas Gerais, Brazil

Site Status

Countries

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Brazil

Other Identifiers

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dessensibilizantes

Identifier Type: -

Identifier Source: org_study_id