Evaluation of a Dual Action Pneumatic Compression Device: Patient Ease of Use and Comfort

NCT ID: NCT02015221

Last Updated: 2016-12-15

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

81 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-11-30

Study Completion Date

2015-08-31

Brief Summary

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The purpose of this study is to determine the ease of use and comfort of the ACTitouch dual action pneumatic compression device in patients with unilateral or bilateral chronic venous insufficiency (CVI) with or without venous leg ulcers, as compared to standard compression.

Detailed Description

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Subjects will be randomized to receive either the ACTitouch system or standard compression garments, and will respond to symptom surveys and quality of life surveys to assess comfort and ease of use of each. These will be conducted at Baseline, at Day 15 and Day 30.

Conditions

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Chronic Venous Insufficiency

Keywords

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chronic venous insufficiency venous leg ulcers pneumatic compression

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Blinding Strategy

NONE

Study Groups

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ACTitouch

ACTitouch in sustained gradient compression mode during all waking hours (at least 10 hours per day) and intermittent pneumatic compression mode for 2 hours each day.

Group Type EXPERIMENTAL

Dual Action Pneumatic Compression Device

Intervention Type DEVICE

A novel dual action pneumatic compression device that provides both sustained compression while ambulatory, and intermittent pneumatic compression when connected to an AC outlet.

Standard Compression Garments

Standard Compression Garments of compression levels 30mmHg to 40mmHg during all waking hours each day.

Group Type ACTIVE_COMPARATOR

Standard Compression Garments

Intervention Type DEVICE

Compression stockings with a 30-40mmHg level of compression.

Interventions

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Dual Action Pneumatic Compression Device

A novel dual action pneumatic compression device that provides both sustained compression while ambulatory, and intermittent pneumatic compression when connected to an AC outlet.

Intervention Type DEVICE

Standard Compression Garments

Compression stockings with a 30-40mmHg level of compression.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Diagnosis of unilateral or bilateral CVI with or without leg ulcers
* Documented history of low adherence to compression garment therapy
* CEAP classification C3-C6
* Leg circumferences within the following ranges: Ankle 12-44cm, calf 22-6m, below the knee 22-68cm

Exclusion Criteria

* History of skin sensitivity to any of the components of ACTitouch or compression garments
* History of acute (deep vein thrombosis) DVT or (pulmonary embolism) PE within the last 3 months
* Ankle Brachial Index (ABI) \< 0.8
* Acute thrombophlebitis
* History of pulmonary edema or decompensated congestive heart failure
* Currently has an active infection of the skin such as cellulitis requiring antibiotics
* Poorly controlled diabetes with an HbA1c value of \>10%
* Exhibits any condition which, according to the PI, justifies the subjects exclusion from the study, such as a medical condition where an increase in venous or lymphatic return is undesirable.
* Subjects with open ulcers must be able to follow their care regimen for ulcer healing concurrently with the assigned study regimen.
* Participating in another clinical trial
* Changes to medications that affect edema within the last 30 days
* Currently pregnant or trying to become pregnant
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Tactile Medical

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Fedor Lurie, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Associate Director, Jobst Vascular Institute

Locations

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Associated Foot and Ankle Specialists, LLC

Phoenix, Arizona, United States

Site Status

Empire Orthopedic Center

Colton, California, United States

Site Status

University of California, San Diego

La Jolla, California, United States

Site Status

VA Loma Linda Healthcare System

Loma Linda, California, United States

Site Status

Long Beach VA Healthcare System

Long Beach, California, United States

Site Status

Park Nicollet Heart and Vascular Center

Minneapolis, Minnesota, United States

Site Status

Stony Brook Vein Center

Stony Brook, New York, United States

Site Status

University Hospitals Case Medical Center

Cleveland, Ohio, United States

Site Status

Ohio Health System

Columbus, Ohio, United States

Site Status

Jobst Vascular Institute

Toledo, Ohio, United States

Site Status

Greenville Hospital System

Greenville, South Carolina, United States

Site Status

Countries

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United States

References

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Lurie F, Schwartz M. Patient-centered outcomes of a dual action pneumatic compression device in comparison to compression stockings for patients with chronic venous disease. J Vasc Surg Venous Lymphat Disord. 2017 Sep;5(5):699-706.e1. doi: 10.1016/j.jvsv.2017.06.003.

Reference Type DERIVED
PMID: 28818225 (View on PubMed)

Other Identifiers

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ACTitouch EOU

Identifier Type: -

Identifier Source: org_study_id