Heart Rate Variability & Fatty Acid Status: Haemodialysis Patients

NCT ID: NCT02014792

Last Updated: 2020-11-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

52 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-08-31

Study Completion Date

2016-03-31

Brief Summary

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Studies suggest that dietary omega-3 fatty acids influence the extent to which the time interval between each heart beat varies (heart rate variability; HRV). Low HRV is associated with increased risk of sudden cardiac death (SCD). The purpose of this research is to investigate the relationship between 24 hour parameters of HRV and blood omega-3 fatty acid levels in patients who have recently commenced haemodialysis.

Detailed Description

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Conditions

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Chronic Kidney Disease

Keywords

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Haemodialysis Heart rate variability n-3 PUFA

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Chronic kidney disease, stage 5

Patients with stage 5 chronic kidney disease who have recently commenced haemodialysis treatment (within 6-10 weeks of starting treatment)

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* CKD stage 5 commencing haemodialysis,
* male or female,
* aged 40-80 y,
* written informed consent

Exclusion Criteria

* history of chronic liver disease or neuropathy, infection or antibiotics within the last month.
Minimum Eligible Age

40 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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King's College Hospital NHS Trust

OTHER

Sponsor Role collaborator

King's College London

OTHER

Sponsor Role lead

Responsible Party

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Dr Wendy Hall

Lecturer in Nutritional Sciences

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Wendy Hall, PhD

Role: PRINCIPAL_INVESTIGATOR

King's College London

Iain Macdougall, FRCP

Role: STUDY_CHAIR

King's College Hospital NHS Trust

Locations

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King's College London

London, , United Kingdom

Site Status

King's College Hospital

London, , United Kingdom

Site Status

Guy's and St Thomas' Hospital

London, , United Kingdom

Site Status

Countries

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United Kingdom

References

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Pinto, A., MacLaughlin, H., Gray, R., & Hall, W. (2020). Heart rate variability and long chain n-3 PUFA in patients with chronic kidney disease commencing haemodialysis: A cross-sectional study. Proceedings of the Nutrition Society, 79(OCE2), E643. doi:10.1017/S0029665120005923

Reference Type RESULT

Related Links

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Other Identifiers

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DNS9195677

Identifier Type: -

Identifier Source: org_study_id