Trial Outcomes & Findings for Dispatcher-Activated Neighborhood Access Defibrillation and Cardiopulmonary Resuscitation (NCT NCT02010151)

NCT ID: NCT02010151

Last Updated: 2020-03-30

Results Overview

we compared the survival to discharge rate between before intervention period and intervention period. Survival to discharge checked at the discharge point of hospital.

• Recruitment status: COMPLETED
• Study phase: NA
• Target enrollment: 3194 participants
• Primary outcome timeframe: discharge time from first admission from emergency department within 2 month
• Results posted on: 2020-03-30

Participant Flow

Participant milestones

Measure	Conventional Dispatcher Assisted CPR patients enrolled in period that conventional dispatcher assisted CPR was provided to patient (January 2013 to April 2015). baseline EMS assessed OHCA: 2,418 * Adult * presumed cardiac etiology * Resuscitation attempted * Not witnessed by EMS provider * Eligible for analysis Final population : 1498	NAD-CPR patients enrolled in period that NAD-CPR was provided to patient (May 2015 to December 2017) baseline EMS assessed OHCA: 2,611 * Adult * presumed cardiac etiology * Resuscitation attempted * Not witnessed by EMS provider * Eligible for analysis Final population : 1,696 (TM sent: 598)
Overall Study STARTED	1498	1696
Overall Study COMPLETED	1498	1696
Overall Study NOT COMPLETED	0	0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Measure	Conventional Dispatcher CPR n=1498 Participants patients enrolled in period that conventional dispatcher CPR was provided to the patients.	NAD-CPR n=1696 Participants patients enrolled in period that NAD-CPR was provided to the patients.	Total n=3194 Participants Total of all reporting groups
Age, Continuous	71 years n=1498 Participants	72 years n=1696 Participants	72 years n=3194 Participants
Sex: Female, Male Female	532 Participants n=1498 Participants	577 Participants n=1696 Participants	1109 Participants n=3194 Participants
Sex: Female, Male Male	966 Participants n=1498 Participants	1119 Participants n=1696 Participants	2085 Participants n=3194 Participants
Race and Ethnicity Not Collected	—	—	0 Participants Race and Ethnicity were not collected from any participant.
Region of Enrollment South Korea	1498 Participants n=1498 Participants	1696 Participants n=1696 Participants	3194 Participants n=3194 Participants
TM sent	0 Participants n=1498 Participants	598 Participants n=1696 Participants	598 Participants n=3194 Participants

PRIMARY outcome

Timeframe: discharge time from first admission from emergency department within 2 month

Population: Study population excluding exclusion criteria

we compared the survival to discharge rate between before intervention period and intervention period.

Survival to discharge checked at the discharge point of hospital.

Outcome measures

Measure	Conventional Dispatcher CPR n=1498 Participants patients enrolled in period that conventional dispatcher CPR was provided to the patients.	NAD-CPR n=1696 Participants patients enrolled in period that NAD-CPR was provided to the patients.
Number of Participants Surviving at Hospital Discharge	135 Participants	216 Participants

SECONDARY outcome

Timeframe: hospital arriving time from ambulance within 2 hours

we compared the Pre-hospital return of spontaneous circulation (ROSC) rate between before intervention period and intervention period.

Outcome measures

Measure	Conventional Dispatcher CPR n=1498 Participants patients enrolled in period that conventional dispatcher CPR was provided to the patients.	NAD-CPR n=1696 Participants patients enrolled in period that NAD-CPR was provided to the patients.
Number of Participants With Pre-Hospital Return of Spontaneous Circulation (ROSC)	107 Participants	223 Participants

SECONDARY outcome

Timeframe: discharge time from first admission from emergency department within 2 month

Cerebral performance category 1 or 2 is defined as good neurological recovery. we compared the good neurological recovery rate between before intervention period and intervention period.

Outcome measures

Measure	Conventional Dispatcher CPR n=1498 Participants patients enrolled in period that conventional dispatcher CPR was provided to the patients.	NAD-CPR n=1696 Participants patients enrolled in period that NAD-CPR was provided to the patients.
Number of Participants With Good Neurological Recovery	68 Participants	140 Participants

Adverse Events

Conventional Dispatcher CPR

Serious events: 1363 serious events

Other events: 0 other events

Deaths: 1363 deaths

NAD-CPR

Serious events: 1480 serious events

Other events: 0 other events

Deaths: 1480 deaths

Serious adverse events

Measure	Conventional Dispatcher CPR n=1498 participants at risk patients enrolled in period that conventional dispatcher CPR was provided to the patients.	NAD-CPR n=1696 participants at risk patients enrolled in period that NAD-CPR was provided to the patients.
Cardiac disorders death	91.0% 1363/1498 • Number of events 1363 • from hospital arrival (from ambulance) to the hospital or ED discharge within 2 month (All patients have different time frame because all patients have different admission period)	87.3% 1480/1696 • Number of events 1480 • from hospital arrival (from ambulance) to the hospital or ED discharge within 2 month (All patients have different time frame because all patients have different admission period)

Other adverse events

Adverse event data not reported

Additional Information

Dr. Sun Young Lee

Seoul National University Hospital

Phone: +82-10-9269-2376

Email: sy2376@gmail.com

Results disclosure agreements

• Principal investigator is a sponsor employee
• Publication restrictions are in place