A Comparison of Farabloc Fabric With Placebo on Alleviation Hot Flash in Menopausal Women

NCT ID: NCT02006238

Last Updated: 2014-06-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-02-28

Study Completion Date

2014-12-31

Brief Summary

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This is a prospective, randomized, double-blind, crossover study. The purpose of this study is to determine whether Farabloc fabric is effective in alleviation of hot flash symptoms in menopausal women. This study will require all prospective participants to fill out a week of Hot Flash Diary to determine eligibility before beginning the study. All prospective participants will be assessed for hot flash frequency, hot flash distress and hot flash severity according to their perception in the Hot Flash Diary during the experimental period.

Detailed Description

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Fifty menopausal volunteers will be randomly assigned to two groups, one receiving Farabloc fabric containing Farabloc (experimental), and the other a similar-appearing fabric made of Nylon (placebo).

All eligible participants will be selected by the initial interview. The following information will be collected during interview process.

* Address
* Medical history
* Concomitant medication
* Allergies

Participants will be asked the following:

1. On a scale from 1 to 10, how much are you bothered by your hot flashes?
2. Do these hot flashes wake you up at night? Around how many times do they occur at night?
3. What are you expectations about this study?

A Menopause Rating Scale questionnaire will be completed by the potential participant to assess symptoms Eligible patients from each group will initially undergo a 7 day washout period before intervention in order to eliminate any effects of hormone replacement therapies (HRT) or herbal supplements that subjects may be using prior to participation in the study. Subjects will be randomized to receive a Farabloc fabric or placebo fabric for one week. After this, the two groups will undergo a second 7 day washout period before crossing over to the other fabric. Once crossed over, participants will use the allocated fabrics for another week.

Participants will be asked not to take their usual HRT or herbal supplements for the entire experimental duration in this study in order to produce impartial, precise and reliable results.

The manufacturer will assign codes for placebo fabric or experimental Farabloc. The randomization code will be broken at the completion of the study for data analysis.

Conditions

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Menopause

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Farabloc

The participants will sleep on Farabloc fabric nightly for a week.

Group Type EXPERIMENTAL

Farabloc

Intervention Type DEVICE

The participants will be randomly received Farabloc (experimental) for one week, followed by a 7 day washout and then crossed over to received the Nylon fabric (placebo) for one week.

Nylon Fabric

Intervention Type DEVICE

The participants will be randomly received Nylon fabric (placebo) for one week, followed by a 7 day washout and then crossed over to receive Farabloc (experimental) for one week.

Nylon Fabric

The participants will sleep on Nylon fabric nightly for week.

Group Type PLACEBO_COMPARATOR

Farabloc

Intervention Type DEVICE

The participants will be randomly received Farabloc (experimental) for one week, followed by a 7 day washout and then crossed over to received the Nylon fabric (placebo) for one week.

Nylon Fabric

Intervention Type DEVICE

The participants will be randomly received Nylon fabric (placebo) for one week, followed by a 7 day washout and then crossed over to receive Farabloc (experimental) for one week.

Interventions

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Farabloc

The participants will be randomly received Farabloc (experimental) for one week, followed by a 7 day washout and then crossed over to received the Nylon fabric (placebo) for one week.

Intervention Type DEVICE

Nylon Fabric

The participants will be randomly received Nylon fabric (placebo) for one week, followed by a 7 day washout and then crossed over to receive Farabloc (experimental) for one week.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Women with 12 months amenorrhea
* Experiencing more than 2 nocturnal hot flashes nightly.

Exclusion Criteria

* Other medical conditions associated with night sweats
* Currently on medication associated with night sweats
* Less than 2 nocturnal hot flashes per night
* Allergies to metals
* Abnormal mental status
* MRS scale rating of mild or above
* Currently on hormone replacement therapy or herbal supplements and cannot safety discontinue these for the duration of the study.
Minimum Eligible Age

45 Years

Maximum Eligible Age

60 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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University of British Columbia

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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York N Hsiang, MB FRCSC

Role: PRINCIPAL_INVESTIGATOR

University of British Columbia, Division of Vascular Surgery and Vancouver General Hospital

Locations

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Dr. Hsiang's office, 510-943 W. Broadway

Vancouver, British Columbia, Canada

Site Status RECRUITING

Countries

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Canada

Central Contacts

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York N Hsiang, MB FRCSC

Role: CONTACT

604.876.5882

Rollin Y Yu

Role: CONTACT

778.321.7921

Facility Contacts

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York N Hsiang, MB FRCSC

Role: primary

604.876.5882

Other Identifiers

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H13-03052

Identifier Type: -

Identifier Source: org_study_id

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