Trial Outcomes & Findings for Preemptive Femoral & Lateral Femoral Cutaneous Nerve Blocks for THA Acute Pain (NCT NCT01997567)

NCT ID: NCT01997567

Last Updated: 2018-10-03

Results Overview

The primary outcome measure will be pain scores at rest (NRS 0-10). Those scores will be documented at initial visit prior to surgery, and at postoperative office visits at 3 weeks, 3 months and 6 months post-procedure.

Recruitment status

TERMINATED

Study phase

NA

Target enrollment

3 participants

Primary outcome timeframe

Preoperative 2-8 wks

Results posted on

2018-10-03

Participant Flow

Participant milestones

Participant milestones
Measure
Grp 1 Ropivacaine Block
Group 1 consented subjects will receive for their hip arthroscopy procedures general anesthesia (sevoflurane) with single femoral and lateral femoral cutaneous nerve blocks under ultrasound guidance, with 20 ml solution for the femoral block and 10 ml for lateral femoral cutaneous block, for a total of 30 ml solution of ropivacaine 0.5% with epinephrine 1:200,000 (150mcg) as a tracer for intravascular injection (total 30 ml) Ropivacaine: Subjects will receive for their hip arthroscopy procedures general anesthesia (sevoflurane) with single femoral and lateral femoral cutaneous nerve blocks under ultrasound guidance, with 20 ml solution for the femoral block and 10 ml for lateral femoral cutaneous block, for a total of 30 ml solution of ropivacaine 0.5% with epinephrine 1:200,000 (150mcg) as a tracer for intravascular injection (total 30 ml)
Grp 2 Placebo Block
Group 2 consented subjects will receive for their hip arthroscopy procedures general anesthesia (sevoflurane) with single femoral and lateral femoral cutaneous nerve blocks under ultrasound guidance, with 20 ml solution for the femoral block and 10 ml for lateral femoral cutaneous block, for a total of 30 ml solution of saline with epinephrine 1:200,000 (150 mcg) (total 30 ml) Placebo: Group 2 consented subjects will receive for their hip arthroscopy procedures general anesthesia (sevoflurane) with single femoral and lateral femoral cutaneous nerve blocks under ultrasound guidance, with 20 ml solution for the femoral block and 10 ml for lateral femoral cutaneous block, for a total of 30 ml solution of saline with epinephrine 1:200,000 (150 mcg) (total 30 ml)
Overall Study
STARTED
0
0
Overall Study
COMPLETED
0
0
Overall Study
NOT COMPLETED
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Preemptive Femoral & Lateral Femoral Cutaneous Nerve Blocks for THA Acute Pain

Baseline characteristics by cohort

Baseline data not reported

PRIMARY outcome

Timeframe: Preoperative 2-8 wks

Population: Study was closed due to enrollment issues and data were not collected or analyzed.

The primary outcome measure will be pain scores at rest (NRS 0-10). Those scores will be documented at initial visit prior to surgery, and at postoperative office visits at 3 weeks, 3 months and 6 months post-procedure.

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: 3 wks postoperative

Population: Study was closed due to enrollment issues and data were not collected or analized.

The primary outcome measure will be pain scores at rest (NRS 0-10). Those scores will be documented at initial visit prior to surgery, and at postoperative office visits at 3 weeks, 3 months and 6 months post-procedure. Study was closed due to enrollment issues and data were not collected or analized.

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: 3 months postoperative

Population: Study was closed due to enrollment issues and data were not collected or analyzed.

The primary outcome measure will be pain scores at rest (NRS 0-10). Those scores will be documented at initial visit prior to surgery, and at postoperative office visits at 3 weeks, 3 months and 6 months post-procedure.

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: 6 months postoperative

Population: Study was closed due to enrollment issues and data were not collected or analyzed.

The primary outcome measure will be pain scores at rest (NRS 0-10). Those scores will be documented at initial visit prior to surgery, and at postoperative office visits at 3 weeks, 3 months and 6 months post-procedure.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Preoperative 2-8 wks

Population: Study was closed due to enrollment issues and data were not collected or analyzed.

Preoperative VR-12 scores will be compared with the VR-12 scores obtained at the 3 mo and 6 mo postoperative visits.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 3 months postoperative

Population: Study was closed due to enrollment issues and data were not collected or analyzed.

Preoperative VR-12 scores will be compared with the VR-12 scores obtained at the 3 mo and 6 mo postoperative visits.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 6 months postoperative

Population: Study was closed due to enrollment issues and data were not collected or analyzed.

Preoperative VR-12 scores will be compared with the VR-12 scores obtained at the 3 mo and 6 mo postoperative visits.

Outcome measures

Outcome data not reported

Adverse Events

Grp 1 Ropivacaine Block

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Grp 2 Placebo Block

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Sandeep Amin, M.D

Rush University Medical Center Department of Anesthesiology

Phone: 312-942-6449

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place