Safety and Performance Investigation of a New 1-piece Ostomy Product Compared to Standard of Care 1-piece in Subjects With Ileostomy

NCT ID: NCT01994863

Last Updated: 2015-03-11

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

View full results

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

TERMINATED

Clinical Phase

PHASE2

Total Enrollment

23 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-09-30

Study Completion Date

2012-11-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The objective of the investigation is to document New Mio 1-piece is non-inferior (no worse) in reducing leakage (4-point scale) compared to Standard of Care.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Ileostomy - Stoma

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

First Coloplast Test product; then Standard Care (see below)

The subjects are randomised to test Coloplast Test product first and thereafter test Standard Care.

Standard Care is a collection of three different already marketed 1-piece flat ostomy appliances. These are Coloplast Sensura 1-piece; Hollister: Moderma 1-piece and B.Braun Flexima 1-piece.

The three Standard Care products were tested in a 1:1:1 randomisation.

Group Type EXPERIMENTAL

Coloplast Test product

Intervention Type DEVICE

Coloplast test product is a newly developed 1-piece ostomy appliance

Standard Care

Intervention Type DEVICE

Standard care consists of three already marketed 1-piece ostomy products

Coloplast SenSura Hollister Moderma/Moderma Flex B.Braun Flexima/Softima

First Standard Care (see below); Then coloplast test product

The subjects are randomised to test Standard care first and thereafter test Coloplast test product.

Standard Care is a collection of three different already marketed 1-piece flat ostomy appliances. These are Coloplast Sensura 1-piece; Hollister: Moderma 1-piece and B.Braun Flexima 1-piece.

The three Standard Care products were tested in a 1:1:1 randomisation.

Group Type EXPERIMENTAL

Coloplast Test product

Intervention Type DEVICE

Coloplast test product is a newly developed 1-piece ostomy appliance

Standard Care

Intervention Type DEVICE

Standard care consists of three already marketed 1-piece ostomy products

Coloplast SenSura Hollister Moderma/Moderma Flex B.Braun Flexima/Softima

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Coloplast Test product

Coloplast test product is a newly developed 1-piece ostomy appliance

Intervention Type DEVICE

Standard Care

Standard care consists of three already marketed 1-piece ostomy products

Coloplast SenSura Hollister Moderma/Moderma Flex B.Braun Flexima/Softima

Intervention Type DEVICE

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Coloplast 1-piece test product Coloplast SenSura Hollister Moderma/Moderma Flex B.Braun Flexima/Softima

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

1. Have given written informed consent
2. Be at least 18 years of age and have full legal capacity
3. Be able to handle the appliance themselves or with help from caregiver (e.g. spouse)
4. Have an ileostomy with a diameter between 15 and 45 mm
5. Have had their ostomy for at least three months
6. Currently use a 1-piece flat product with open bag
7. Use minimum 1 product every second day.
8. Be suitable for participation in the investigation and for using a standard adhesive, flat base plate
9. Must use custom cut product
10. Accept to test two 1-piece products within the study

Exclusion Criteria

1. Use irrigation during the study (flush the stoma with water)
2. Currently receiving or have within the past 2 months received radio- and/or chemotherapy
3. Currently receiving or have within the past month received systemic steroid or local treatment in the peristomal area
4. Are pregnant or breastfeeding
5. Participating in other interventional clinical investigations or have previously participated in this investigation
6. Has more than three days wear time
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Coloplast A/S

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Daniel Carter, MSc

Role: STUDY_DIRECTOR

Coloplast A/S

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

QPS Netherland B.V.

Groningen, , Netherlands

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Netherlands

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

CP224

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

CP376 OCT Exploratory Skin Study
NCT06965140 COMPLETED NA