Trial Outcomes & Findings for On the Move: Optimizing Participation in Group Exercise (NCT NCT01986647)

NCT ID: NCT01986647

Last Updated: 2019-03-22

Results Overview

Late Life Function and Disability Index (LLFDI) overall function. Scores range from 0-100 with higher score representing better function.

• Recruitment status: COMPLETED
• Study phase: NA
• Target enrollment: 424 participants
• Primary outcome timeframe: baseline and 12 weeks
• Results posted on: 2019-03-22

Participant Flow

Recruitment occurred between April 2014 through January 2016. Potential participants were recruited from independent living facilities, senior apartment buildings, and senior community centers.

Participant milestones

Measure	On the Move Exercise Group - Exercise Leader On the Move group exercise - 2 times per week for 12 weeks. Each session lasts approximately 1 hour. Timing and coordination exercises to improve walking. Taught by exercise leader. On the Move group exercise	Standard Group Exercise Program - Exercise Leader Standard impairment based seated group exercise program. 2 times per week for 12 weeks, approximately 1 hour class. Taught by exercise leader Standard group exercise	On the Move Exercise Program - Staff Activity Personnel On the Move group exercise - taught by staff activity personnel	Standard Exercise Program - Staff Activity Personnel Standard exercise program taught by a member of the facility who does not necessarily have formal exercise training. this person will be trained by the research staff to lead the class. Standard group exercise
Overall Study STARTED	152	146	49	77
Overall Study COMPLETED	142	139	37	66
Overall Study NOT COMPLETED	10	7	12	11

Reasons for withdrawal

Measure	On the Move Exercise Group - Exercise Leader On the Move group exercise - 2 times per week for 12 weeks. Each session lasts approximately 1 hour. Timing and coordination exercises to improve walking. Taught by exercise leader. On the Move group exercise	Standard Group Exercise Program - Exercise Leader Standard impairment based seated group exercise program. 2 times per week for 12 weeks, approximately 1 hour class. Taught by exercise leader Standard group exercise	On the Move Exercise Program - Staff Activity Personnel On the Move group exercise - taught by staff activity personnel	Standard Exercise Program - Staff Activity Personnel Standard exercise program taught by a member of the facility who does not necessarily have formal exercise training. this person will be trained by the research staff to lead the class. Standard group exercise
Overall Study Lost to Follow-up	4	1	4	4
Overall Study Withdrawal by Subject	1	3	2	3
Overall Study Health	5	3	6	4

Baseline Characteristics

On the Move: Optimizing Participation in Group Exercise

Baseline characteristics by cohort

Measure	On the Move Exercise Group - Exercise LEader n=152 Participants On the Move group exercise - 2 times per week for 12 weeks. Each session lasts approximately 1 hour. Timing and coordination exercises to improve walking. Exercise class will be led by a person who is trained in exercise such as exercise physiologist, physical therapist, physical therapist assistant On the Move group exercise	Standard Group Exercise Program - Exercise Leader n=146 Participants Standard impairment based seated group exercise program. 2 times per week for 12 weeks, approximately 1 hour class. Exercise class will be led by a person who is trained in exercise such as exercise physiologist, physical therapist, physical therapist assistant Standard group exercise	On the Move Group - STaff Activity Personnel n=49 Participants On the Move group exercise - 2 times per week for 12 weeks. Each session lasts approximately 1 hour. Timing and coordination exercises to improve walking. Exercise class will be led by a member of the facility who does not necessarily have formal exercise training. this person will be trained by the research staff to lead the class. On the Move group exercise	Standard Program - Staff Activity Personnel n=77 Participants Standard impairment based seated group exercise program. 2 times per week for 12 weeks, approximately 1 hour class. Exercise class will be led by a member of the facility who does not necessarily have formal exercise training. this person will be trained by the research staff to lead the class. Standard group exercise	Total n=424 Participants Total of all reporting groups
Age, Continuous	79.6 years STANDARD_DEVIATION 8.2 • n=5 Participants	80.5 years STANDARD_DEVIATION 8.1 • n=7 Participants	83.7 years STANDARD_DEVIATION 6.2 • n=5 Participants	81.7 years STANDARD_DEVIATION 7.0 • n=4 Participants	80.7 years STANDARD_DEVIATION 7.8 • n=21 Participants
Sex: Female, Male Female	131 Participants n=5 Participants	120 Participants n=7 Participants	40 Participants n=5 Participants	58 Participants n=4 Participants	349 Participants n=21 Participants
Sex: Female, Male Male	21 Participants n=5 Participants	26 Participants n=7 Participants	9 Participants n=5 Participants	19 Participants n=4 Participants	75 Participants n=21 Participants
Region of Enrollment United States	152 participants n=5 Participants	146 participants n=7 Participants	49 participants n=5 Participants	77 participants n=4 Participants	424 participants n=21 Participants
Intervention Setting Community center	36 Participants n=5 Participants	29 Participants n=7 Participants	13 Participants n=5 Participants	14 Participants n=4 Participants	92 Participants n=21 Participants
Intervention Setting Independent living facility	42 Participants n=5 Participants	61 Participants n=7 Participants	29 Participants n=5 Participants	44 Participants n=4 Participants	176 Participants n=21 Participants
Intervention Setting Apartment building	74 Participants n=5 Participants	56 Participants n=7 Participants	7 Participants n=5 Participants	19 Participants n=4 Participants	156 Participants n=21 Participants
Married	29 Participants n=5 Participants	30 Participants n=7 Participants	22 Participants n=5 Participants	18 Participants n=4 Participants	99 Participants n=21 Participants
College education	67 Participants n=5 Participants	73 Participants n=7 Participants	28 Participants n=5 Participants	47 Participants n=4 Participants	215 Participants n=21 Participants
Comorbidities	2.9 units on a scale STANDARD_DEVIATION 1.4 • n=5 Participants	2.7 units on a scale STANDARD_DEVIATION 1.5 • n=7 Participants	2.8 units on a scale STANDARD_DEVIATION 1.3 • n=5 Participants	3.0 units on a scale STANDARD_DEVIATION 1.3 • n=4 Participants	2.8 units on a scale STANDARD_DEVIATION 1.4 • n=21 Participants
Fear of falling	53 Participants n=5 Participants	57 Participants n=7 Participants	17 Participants n=5 Participants	21 Participants n=4 Participants	148 Participants n=21 Participants
fall in previous year	45 Participants n=5 Participants	41 Participants n=7 Participants	16 Participants n=5 Participants	26 Participants n=4 Participants	128 Participants n=21 Participants
Excellent/Very good mobility	90 Participants n=5 Participants	90 Participants n=7 Participants	30 Participants n=5 Participants	37 Participants n=4 Participants	247 Participants n=21 Participants
Excellent/very good health	80 Participants n=5 Participants	75 Participants n=7 Participants	32 Participants n=5 Participants	38 Participants n=4 Participants	225 Participants n=21 Participants
Excellent/very good balance	47 Participants n=5 Participants	51 Participants n=7 Participants	14 Participants n=5 Participants	19 Participants n=4 Participants	131 Participants n=21 Participants
Height	1.61 meters STANDARD_DEVIATION 0.10 • n=5 Participants	1.61 meters STANDARD_DEVIATION 0.13 • n=7 Participants	1.6 meters STANDARD_DEVIATION 0.2 • n=5 Participants	1.6 meters STANDARD_DEVIATION 0.1 • n=4 Participants	1.6 meters STANDARD_DEVIATION 0.12 • n=21 Participants
Weight	75.3 kg STANDARD_DEVIATION 21.1 • n=5 Participants	71.9 kg STANDARD_DEVIATION 15.7 • n=7 Participants	74.1 kg STANDARD_DEVIATION 32.0 • n=5 Participants	74.3 kg STANDARD_DEVIATION 18.0 • n=4 Participants	73.8 kg STANDARD_DEVIATION 20.5 • n=21 Participants
Body Mass Index	29.03 kg/m2 STANDARD_DEVIATION 7.59 • n=5 Participants	28.62 kg/m2 STANDARD_DEVIATION 15.76 • n=7 Participants	31.4 kg/m2 STANDARD_DEVIATION 24.3 • n=5 Participants	27.6 kg/m2 STANDARD_DEVIATION 6.1 • n=4 Participants	28.9 kg/m2 STANDARD_DEVIATION 13.4 • n=21 Participants
Six minute walk distance	273.3 meters STANDARD_DEVIATION 88.0 • n=5 Participants	277.3 meters STANDARD_DEVIATION 95.5 • n=7 Participants	276.2 meters STANDARD_DEVIATION 88.7 • n=5 Participants	282.8 meters STANDARD_DEVIATION 82.6 • n=4 Participants	276.8 meters STANDARD_DEVIATION 89.6 • n=21 Participants
LLFDI function	58.9 units on a scale STANDARD_DEVIATION 8.5 • n=5 Participants	60.0 units on a scale STANDARD_DEVIATION 10.5 • n=7 Participants	59.6 units on a scale STANDARD_DEVIATION 8.6 • n=5 Participants	59.8 units on a scale STANDARD_DEVIATION 9.5 • n=4 Participants	59.5 units on a scale STANDARD_DEVIATION 9.4 • n=21 Participants
LLFDI disability	53.3 units on a scale STANDARD_DEVIATION 6.5 • n=5 Participants	51.6 units on a scale STANDARD_DEVIATION 5.8 • n=7 Participants	54.0 units on a scale STANDARD_DEVIATION 6.6 • n=5 Participants	52.6 units on a scale STANDARD_DEVIATION 6.7 • n=4 Participants	52.7 units on a scale STANDARD_DEVIATION 6.4 • n=21 Participants
Gait speed	0.90 m/s STANDARD_DEVIATION 0.20 • n=5 Participants	0.92 m/s STANDARD_DEVIATION 0.21 • n=7 Participants	0.91 m/s STANDARD_DEVIATION 0.18 • n=5 Participants	0.91 m/s STANDARD_DEVIATION 0.20 • n=4 Participants	0.92 m/s STANDARD_DEVIATION 0.21 • n=21 Participants

PRIMARY outcome

Timeframe: baseline and 12 weeks

Late Life Function and Disability Index (LLFDI) overall function. Scores range from 0-100 with higher score representing better function.

Outcome measures

Measure	On the Move Exercise Group - Exercise Leader n=152 Participants On the Move group exercise - 2 times per week for 12 weeks. Each session lasts approximately 1 hour. Timing and coordination exercises to improve walking. Taught by exercise leader. On the Move group exercise	Standard Group Exercise Program - Exercise Leader n=146 Participants Standard impairment based seated group exercise program. 2 times per week for 12 weeks, approximately 1 hour class. Taught by exercise leader Standard group exercise	On the Move Exercise Program - Staff Activity Personnel n=49 Participants On the Move group exercise - taught by staff activity personnel	Standard Exercise Program - Staff Activity Personnel n=77 Participants Standard exercise program taught by a member of the facility who does not necessarily have formal exercise training. this person will be trained by the research staff to lead the class. Standard group exercise
Change in Self-reported Overall Function From Baseline to 12 Weeks	0.4 units on a scale Standard Error 5.7	-0.6 units on a scale Standard Error 5.8	-1.37 units on a scale Standard Error 4.68	-0.32 units on a scale Standard Error 6.03

PRIMARY outcome

Timeframe: 12 weeks

Late Life Function and Disability Instrument (LLFDI) disability frequency component. Scores range from 0-100 with higher scores representing better (less) disability.

Outcome measures

Measure	On the Move Exercise Group - Exercise Leader n=152 Participants On the Move group exercise - 2 times per week for 12 weeks. Each session lasts approximately 1 hour. Timing and coordination exercises to improve walking. Taught by exercise leader. On the Move group exercise	Standard Group Exercise Program - Exercise Leader n=146 Participants Standard impairment based seated group exercise program. 2 times per week for 12 weeks, approximately 1 hour class. Taught by exercise leader Standard group exercise	On the Move Exercise Program - Staff Activity Personnel n=49 Participants On the Move group exercise - taught by staff activity personnel	Standard Exercise Program - Staff Activity Personnel n=77 Participants Standard exercise program taught by a member of the facility who does not necessarily have formal exercise training. this person will be trained by the research staff to lead the class. Standard group exercise
Change in Self-reported Disability From Baseline to 12 Weeks	0.4 units on a scale Standard Error 4.1	0.7 units on a scale Standard Error 5.0	-1.45 units on a scale Standard Error 6.34	1.26 units on a scale Standard Error 5.66

PRIMARY outcome

Timeframe: 12 weeks

Gait speed in m/s

Outcome measures

Measure	On the Move Exercise Group - Exercise Leader n=152 Participants On the Move group exercise - 2 times per week for 12 weeks. Each session lasts approximately 1 hour. Timing and coordination exercises to improve walking. Taught by exercise leader. On the Move group exercise	Standard Group Exercise Program - Exercise Leader n=146 Participants Standard impairment based seated group exercise program. 2 times per week for 12 weeks, approximately 1 hour class. Taught by exercise leader Standard group exercise	On the Move Exercise Program - Staff Activity Personnel n=49 Participants On the Move group exercise - taught by staff activity personnel	Standard Exercise Program - Staff Activity Personnel n=77 Participants Standard exercise program taught by a member of the facility who does not necessarily have formal exercise training. this person will be trained by the research staff to lead the class. Standard group exercise
Change in Gait Speed From Baseline to 12 Weeks	0.05 m/s Standard Error 0.13	-0.01 m/s Standard Error 0.11	-0.01 m/s Standard Error 0.13	0.02 m/s Standard Error 0.16

PRIMARY outcome

Timeframe: 12 weeks

distance walked in 6 minutes

Outcome measures

Measure	On the Move Exercise Group - Exercise Leader n=152 Participants On the Move group exercise - 2 times per week for 12 weeks. Each session lasts approximately 1 hour. Timing and coordination exercises to improve walking. Taught by exercise leader. On the Move group exercise	Standard Group Exercise Program - Exercise Leader n=146 Participants Standard impairment based seated group exercise program. 2 times per week for 12 weeks, approximately 1 hour class. Taught by exercise leader Standard group exercise	On the Move Exercise Program - Staff Activity Personnel n=49 Participants On the Move group exercise - taught by staff activity personnel	Standard Exercise Program - Staff Activity Personnel n=77 Participants Standard exercise program taught by a member of the facility who does not necessarily have formal exercise training. this person will be trained by the research staff to lead the class. Standard group exercise
Change in Six Minute Walk Distance From Baseline to 12 Weeks	20.6 meters Standard Error 57.1	4.1 meters Standard Error 55.6	9.3 meters Standard Error 72.4	-3.24 meters Standard Error 56.48

SECONDARY outcome

Timeframe: 12 weeks

Participant satisfaction will be measured by satisfaction surveys and personal interviews. Benefited from class a good bit or somewhat

Outcome measures

Measure	On the Move Exercise Group - Exercise Leader n=152 Participants On the Move group exercise - 2 times per week for 12 weeks. Each session lasts approximately 1 hour. Timing and coordination exercises to improve walking. Taught by exercise leader. On the Move group exercise	Standard Group Exercise Program - Exercise Leader n=146 Participants Standard impairment based seated group exercise program. 2 times per week for 12 weeks, approximately 1 hour class. Taught by exercise leader Standard group exercise	On the Move Exercise Program - Staff Activity Personnel n=49 Participants On the Move group exercise - taught by staff activity personnel	Standard Exercise Program - Staff Activity Personnel n=77 Participants Standard exercise program taught by a member of the facility who does not necessarily have formal exercise training. this person will be trained by the research staff to lead the class. Standard group exercise
Number of Participants Who Reported They Benefited a Good Bit or Somewhat From the Class	104 Participants	105 Participants	21 Participants	41 Participants

SECONDARY outcome

Timeframe: 12 weeks

Measured by question on the satisfaction questionnaire. Question asked participants to rate how challenging the class was.

Outcome measures

Measure	On the Move Exercise Group - Exercise Leader n=152 Participants On the Move group exercise - 2 times per week for 12 weeks. Each session lasts approximately 1 hour. Timing and coordination exercises to improve walking. Taught by exercise leader. On the Move group exercise	Standard Group Exercise Program - Exercise Leader n=146 Participants Standard impairment based seated group exercise program. 2 times per week for 12 weeks, approximately 1 hour class. Taught by exercise leader Standard group exercise	On the Move Exercise Program - Staff Activity Personnel n=49 Participants On the Move group exercise - taught by staff activity personnel	Standard Exercise Program - Staff Activity Personnel n=77 Participants Standard exercise program taught by a member of the facility who does not necessarily have formal exercise training. this person will be trained by the research staff to lead the class. Standard group exercise
Number of Participants Who Reported That the Class Was at Least Somewhat Challenging	92 Participants	94 Participants	23 Participants	33 Participants

SECONDARY outcome

Timeframe: 12 weeks

Question from satisfaction questionnaire - that asked participants their opinion on the amount of individualized instruction they received.

Outcome measures

Measure	On the Move Exercise Group - Exercise Leader n=152 Participants On the Move group exercise - 2 times per week for 12 weeks. Each session lasts approximately 1 hour. Timing and coordination exercises to improve walking. Taught by exercise leader. On the Move group exercise	Standard Group Exercise Program - Exercise Leader n=146 Participants Standard impairment based seated group exercise program. 2 times per week for 12 weeks, approximately 1 hour class. Taught by exercise leader Standard group exercise	On the Move Exercise Program - Staff Activity Personnel n=49 Participants On the Move group exercise - taught by staff activity personnel	Standard Exercise Program - Staff Activity Personnel n=77 Participants Standard exercise program taught by a member of the facility who does not necessarily have formal exercise training. this person will be trained by the research staff to lead the class. Standard group exercise
Number of Participants Reporting That They Received a Just Right Amount of Individualized Instruction	128 Participants	124 Participants	25 Participants	53 Participants

SECONDARY outcome

Timeframe: 12 weeks

Question from the satisfaction questionnaire.

Outcome measures

Measure	On the Move Exercise Group - Exercise Leader n=152 Participants On the Move group exercise - 2 times per week for 12 weeks. Each session lasts approximately 1 hour. Timing and coordination exercises to improve walking. Taught by exercise leader. On the Move group exercise	Standard Group Exercise Program - Exercise Leader n=146 Participants Standard impairment based seated group exercise program. 2 times per week for 12 weeks, approximately 1 hour class. Taught by exercise leader Standard group exercise	On the Move Exercise Program - Staff Activity Personnel n=49 Participants On the Move group exercise - taught by staff activity personnel	Standard Exercise Program - Staff Activity Personnel n=77 Participants Standard exercise program taught by a member of the facility who does not necessarily have formal exercise training. this person will be trained by the research staff to lead the class. Standard group exercise
Number of Participants Who Reported That They Felt Safe or Very Safe During the Exercise.	131 Participants	127 Participants	27 Participants	58 Participants

SECONDARY outcome

Timeframe: 12 weeks

Question from the satisfaction questionnaire.

Outcome measures

Measure	On the Move Exercise Group - Exercise Leader n=152 Participants On the Move group exercise - 2 times per week for 12 weeks. Each session lasts approximately 1 hour. Timing and coordination exercises to improve walking. Taught by exercise leader. On the Move group exercise	Standard Group Exercise Program - Exercise Leader n=146 Participants Standard impairment based seated group exercise program. 2 times per week for 12 weeks, approximately 1 hour class. Taught by exercise leader Standard group exercise	On the Move Exercise Program - Staff Activity Personnel n=49 Participants On the Move group exercise - taught by staff activity personnel	Standard Exercise Program - Staff Activity Personnel n=77 Participants Standard exercise program taught by a member of the facility who does not necessarily have formal exercise training. this person will be trained by the research staff to lead the class. Standard group exercise
Number of Participants Who Reported They Were Satisfied or Very Satisfied With the Program.	128 Participants	126 Participants	26 Participants	57 Participants

SECONDARY outcome

Timeframe: 12 weeks

Question from the satisfaction questionnaire.

Outcome measures

Measure	On the Move Exercise Group - Exercise Leader n=152 Participants On the Move group exercise - 2 times per week for 12 weeks. Each session lasts approximately 1 hour. Timing and coordination exercises to improve walking. Taught by exercise leader. On the Move group exercise	Standard Group Exercise Program - Exercise Leader n=146 Participants Standard impairment based seated group exercise program. 2 times per week for 12 weeks, approximately 1 hour class. Taught by exercise leader Standard group exercise	On the Move Exercise Program - Staff Activity Personnel n=49 Participants On the Move group exercise - taught by staff activity personnel	Standard Exercise Program - Staff Activity Personnel n=77 Participants Standard exercise program taught by a member of the facility who does not necessarily have formal exercise training. this person will be trained by the research staff to lead the class. Standard group exercise
Number of Participants Who Reported They Would Definitely or Probably Continue With the Program	113 Participants	108 Participants	26 Participants	56 Participants

SECONDARY outcome

Timeframe: 12 weeks

Time it takes to walk a figure 8 around 2 cones 5 feet apart. Greater time in seconds represents poorer performance

Outcome measures

Measure	On the Move Exercise Group - Exercise Leader n=152 Participants On the Move group exercise - 2 times per week for 12 weeks. Each session lasts approximately 1 hour. Timing and coordination exercises to improve walking. Taught by exercise leader. On the Move group exercise	Standard Group Exercise Program - Exercise Leader n=146 Participants Standard impairment based seated group exercise program. 2 times per week for 12 weeks, approximately 1 hour class. Taught by exercise leader Standard group exercise	On the Move Exercise Program - Staff Activity Personnel n=49 Participants On the Move group exercise - taught by staff activity personnel	Standard Exercise Program - Staff Activity Personnel n=77 Participants Standard exercise program taught by a member of the facility who does not necessarily have formal exercise training. this person will be trained by the research staff to lead the class. Standard group exercise
Change in Figure 8 Walk Test From Baseline to 12 Weeks	-0.67 seconds Standard Deviation 2.02	0.11 seconds Standard Deviation 3.15	-0.1 seconds Standard Deviation 2.1	0.3 seconds Standard Deviation 3.9

SECONDARY outcome

Timeframe: 12 weeks

Confidence in walking was measured by the modified gait efficacy scale (mGES). Scores range from 0-100 with higher scores indicating greater confidence.

Outcome measures

Measure	On the Move Exercise Group - Exercise Leader n=152 Participants On the Move group exercise - 2 times per week for 12 weeks. Each session lasts approximately 1 hour. Timing and coordination exercises to improve walking. Taught by exercise leader. On the Move group exercise	Standard Group Exercise Program - Exercise Leader n=146 Participants Standard impairment based seated group exercise program. 2 times per week for 12 weeks, approximately 1 hour class. Taught by exercise leader Standard group exercise	On the Move Exercise Program - Staff Activity Personnel n=49 Participants On the Move group exercise - taught by staff activity personnel	Standard Exercise Program - Staff Activity Personnel n=77 Participants Standard exercise program taught by a member of the facility who does not necessarily have formal exercise training. this person will be trained by the research staff to lead the class. Standard group exercise
Change in Modified Gait Efficacy Scale From Baseline to 12 Weeks	-0.61 units on a scale Standard Deviation 10.7	-1.51 units on a scale Standard Deviation 12.1	-5.3 units on a scale Standard Deviation 11.6	-4.1 units on a scale Standard Deviation 11.5

SECONDARY outcome

Timeframe: 12 week

Short physical Performance Battery is a performance test that includes gait speed, 5 time sit to stand and standing balance. Scores range from 0-12 with greater scores indicating better performance.

Outcome measures

Measure	On the Move Exercise Group - Exercise Leader n=152 Participants On the Move group exercise - 2 times per week for 12 weeks. Each session lasts approximately 1 hour. Timing and coordination exercises to improve walking. Taught by exercise leader. On the Move group exercise	Standard Group Exercise Program - Exercise Leader n=146 Participants Standard impairment based seated group exercise program. 2 times per week for 12 weeks, approximately 1 hour class. Taught by exercise leader Standard group exercise	On the Move Exercise Program - Staff Activity Personnel n=49 Participants On the Move group exercise - taught by staff activity personnel	Standard Exercise Program - Staff Activity Personnel n=77 Participants Standard exercise program taught by a member of the facility who does not necessarily have formal exercise training. this person will be trained by the research staff to lead the class. Standard group exercise
Change in Short Physical Performance Battery From Baseline to 12weeks	0.16 units on a scale Standard Deviation 1.81	0.17 units on a scale Standard Deviation 1.53	-0.1 units on a scale Standard Deviation 2.4	-0.1 units on a scale Standard Deviation 1.7

SECONDARY outcome

Timeframe: 12 week

variability of individual stance times during walking as measured from a electronic walkway. Measured as the standard deviation of all stance times. greater values represent greater variability which is related to poorer outcomes.

Outcome measures

Measure	On the Move Exercise Group - Exercise Leader n=152 Participants On the Move group exercise - 2 times per week for 12 weeks. Each session lasts approximately 1 hour. Timing and coordination exercises to improve walking. Taught by exercise leader. On the Move group exercise	Standard Group Exercise Program - Exercise Leader n=146 Participants Standard impairment based seated group exercise program. 2 times per week for 12 weeks, approximately 1 hour class. Taught by exercise leader Standard group exercise	On the Move Exercise Program - Staff Activity Personnel n=49 Participants On the Move group exercise - taught by staff activity personnel	Standard Exercise Program - Staff Activity Personnel n=77 Participants Standard exercise program taught by a member of the facility who does not necessarily have formal exercise training. this person will be trained by the research staff to lead the class. Standard group exercise
Change in Stance Time Variability From Baseline to 12weeks	0.002 seconds Standard Deviation 0.03	0.00 seconds Standard Deviation 0.03	0.006 seconds Standard Deviation 0.02	-0.001 seconds Standard Deviation 0.022

SECONDARY outcome

Timeframe: 12 weeks

Time to walk narrow pathway. Greater values (times) indicate poorer performance.

Outcome measures

Measure	On the Move Exercise Group - Exercise Leader n=152 Participants On the Move group exercise - 2 times per week for 12 weeks. Each session lasts approximately 1 hour. Timing and coordination exercises to improve walking. Taught by exercise leader. On the Move group exercise	Standard Group Exercise Program - Exercise Leader n=146 Participants Standard impairment based seated group exercise program. 2 times per week for 12 weeks, approximately 1 hour class. Taught by exercise leader Standard group exercise	On the Move Exercise Program - Staff Activity Personnel n=49 Participants On the Move group exercise - taught by staff activity personnel	Standard Exercise Program - Staff Activity Personnel n=77 Participants Standard exercise program taught by a member of the facility who does not necessarily have formal exercise training. this person will be trained by the research staff to lead the class. Standard group exercise
Change in Narrow Walk Time From Baseline to 12 Weeks	-0.25 seconds Standard Deviation 2.04	-0.04 seconds Standard Deviation 2.39	-0.3 seconds Standard Deviation 1.5	0.1 seconds Standard Deviation 2.6

OTHER_PRE_SPECIFIED outcome

Timeframe: 12 weeks

The number of participants attending 20 or more exercise classes

Outcome measures

Measure	On the Move Exercise Group - Exercise Leader n=152 Participants On the Move group exercise - 2 times per week for 12 weeks. Each session lasts approximately 1 hour. Timing and coordination exercises to improve walking. Taught by exercise leader. On the Move group exercise	Standard Group Exercise Program - Exercise Leader n=146 Participants Standard impairment based seated group exercise program. 2 times per week for 12 weeks, approximately 1 hour class. Taught by exercise leader Standard group exercise	On the Move Exercise Program - Staff Activity Personnel n=49 Participants On the Move group exercise - taught by staff activity personnel	Standard Exercise Program - Staff Activity Personnel n=77 Participants Standard exercise program taught by a member of the facility who does not necessarily have formal exercise training. this person will be trained by the research staff to lead the class. Standard group exercise
Attendance Rates	76 Participants	95 Participants	12 Participants	40 Participants

Adverse Events

On the Move Exercise - Exercise Leader

Serious events: 0 serious events

Other events: 4 other events

Deaths: 0 deaths

Standard Program - Exercise Leader

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

On the Move - Staff Activity Personnel

Serious events: 0 serious events

Other events: 2 other events

Deaths: 0 deaths

Standard - Staff Activity Personnel

Serious events: 1 serious events

Other events: 0 other events

Deaths: 0 deaths

Serious adverse events

Measure	On the Move Exercise - Exercise Leader n=152 participants at risk On the Move group exercise - 2 times per week for 12 weeks. Each session lasts approximately 1 hour. Timing and coordination exercises to improve walking. Led by exercise leader On the Move exercise - exercise leader: exercise physiologists	Standard Program - Exercise Leader n=146 participants at risk Standard impairment based seated group exercise program. 2 times per week for 12 weeks, approximately 1 hour class. Led by exercise leader Standard program - exercise leader: This is an impairment-based exercise program focusing on flexibility, strength and endurance and is taught by research staff who are PTs, PTAs, or exercise physiologists	On the Move - Staff Activity Personnel n=49 participants at risk On the Move group exercise - 2 times per week for 12 weeks. Each session lasts approximately 1 hour. Timing and coordination exercises to improve walking. Led by activity personnel. On the Move exercise - staff activity personnel: this is a group exercise program focusing on the timing and coordination of walking. The program is taught by a person from the facility that the research team trained.	Standard - Staff Activity Personnel n=77 participants at risk Standard impairment based seated group exercise program. 2 times per week for 12 weeks, approximately 1 hour class. Led by staff activity personnel Standard program - staff activity personnel: This is an impairment-based exercise program focusing on flexibility, strength and endurance and is taught by a member of the facility that the research staff trained.
Cardiac disorders chest pain	0.00% 0/152	0.00% 0/146	0.00% 0/49	1.3% 1/77 • Number of events 1

Other adverse events

Measure	On the Move Exercise - Exercise Leader n=152 participants at risk On the Move group exercise - 2 times per week for 12 weeks. Each session lasts approximately 1 hour. Timing and coordination exercises to improve walking. Led by exercise leader On the Move exercise - exercise leader: exercise physiologists	Standard Program - Exercise Leader n=146 participants at risk Standard impairment based seated group exercise program. 2 times per week for 12 weeks, approximately 1 hour class. Led by exercise leader Standard program - exercise leader: This is an impairment-based exercise program focusing on flexibility, strength and endurance and is taught by research staff who are PTs, PTAs, or exercise physiologists	On the Move - Staff Activity Personnel n=49 participants at risk On the Move group exercise - 2 times per week for 12 weeks. Each session lasts approximately 1 hour. Timing and coordination exercises to improve walking. Led by activity personnel. On the Move exercise - staff activity personnel: this is a group exercise program focusing on the timing and coordination of walking. The program is taught by a person from the facility that the research team trained.	Standard - Staff Activity Personnel n=77 participants at risk Standard impairment based seated group exercise program. 2 times per week for 12 weeks, approximately 1 hour class. Led by staff activity personnel Standard program - staff activity personnel: This is an impairment-based exercise program focusing on flexibility, strength and endurance and is taught by a member of the facility that the research staff trained.
Injury, poisoning and procedural complications fall	1.3% 2/152 • Number of events 2	0.00% 0/146	2.0% 1/49 • Number of events 1	0.00% 0/77
Musculoskeletal and connective tissue disorders pain	0.66% 1/152 • Number of events 1	0.00% 0/146	0.00% 0/49	0.00% 0/77
Respiratory, thoracic and mediastinal disorders fatigue	0.66% 1/152 • Number of events 1	0.00% 0/146	2.0% 1/49 • Number of events 1	0.00% 0/77

Additional Information

Jennifer S. Brach, PhD, PT

University of Pittsburgh

Phone: 412-383-6533

Email: jbrach@pitt.edu

Results disclosure agreements

• Principal investigator is a sponsor employee
• Publication restrictions are in place