Barbed Suture in Single-port Laparoscopic Myomectomy

NCT ID: NCT01984632

Last Updated: 2015-07-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-11-30

Study Completion Date

2014-12-31

Brief Summary

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The aim of this study is to test our hypothesis that the use of unidirectional knotless barbed suture in single-port laparoscopic myomectomy could facilitate the suture of uterine wall defect after myoma enucleation as multi-port laparoscopic myomectomy did.

Detailed Description

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The investigators plan to perform a multi-center randomized clinical trial on women scheduled for laparoscopic myomectomy. All women will get the same preoperative and postoperative care. Women will be assigned by chance to one of two groups: one group will receive single-port laparoscopic myomectomy using V-Loc™ suture material (study group). The other group will receive conventional multi-port laparoscopic myomectomy using V-Loc™ suture material (control group). The investigators will collect information on suturing time and complications related to surgery.

Conditions

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Uterine Myoma

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Single-port laparoscopic myomectomy

We will use barbed suture (V-Loc) under intervention of single-port laparoscopic myomectomy

Group Type EXPERIMENTAL

Single-port laparoscopic myomectomy

Intervention Type PROCEDURE

The aim of this study is to compare single-port laparoscopic myomectomy using barbed suture (experimental group) with multi-port laparoscopic myomectomy using barbed suture (control group) in terms of operative time (esp. suturing time).

Multi-port laparoscopic myomectomy

We will use barbed suture(V-Loc) under intervention of multi-port laparoscopic myomectomy.

Group Type ACTIVE_COMPARATOR

Multi-port laparoscopic myomectomy

Intervention Type PROCEDURE

The aim of this study is to compare single-port laparoscopic myomectomy using barbed suture (experimental group) with multi-port laparoscopic myomectomy using barbed suture(control group) in terms of operative time (esp. suturing time).

Interventions

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Single-port laparoscopic myomectomy

The aim of this study is to compare single-port laparoscopic myomectomy using barbed suture (experimental group) with multi-port laparoscopic myomectomy using barbed suture (control group) in terms of operative time (esp. suturing time).

Intervention Type PROCEDURE

Multi-port laparoscopic myomectomy

The aim of this study is to compare single-port laparoscopic myomectomy using barbed suture (experimental group) with multi-port laparoscopic myomectomy using barbed suture(control group) in terms of operative time (esp. suturing time).

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Age between 18 and 55 years
* Image-confirmed uterine myoma
* Number of myoma ≤2 and largest size ≤10cm
* Women who were scheduled to have laparoscopic myomectomy
* Appropriate medical status for laparoscopic surgery (American Society of Anesthesiologists Physical Status classification 1 or 2)

Exclusion Criteria

* Women with pedunculated subserosal myoma or submucosal myoma
* Women undergoing concomitant complex surgical procedures at the time of laparoscopic myomectomy such as severe adhesiolysis or resection for severe endometriosis
* Women with any suggestion of malignant uterine or adnexal diseases
* Women with diabetics, malignancy, or malnutrition, which can affect wound healing
* Women having major medical comorbidity or psychiatric illness, which could affect follow-up and/or compliance
* Women who refuse to participate or give consent to the procedures
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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CHA University

OTHER

Sponsor Role lead

Responsible Party

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Taejong Song

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Taejong Song, MD

Role: PRINCIPAL_INVESTIGATOR

CHA Gangnam Medical Center, CHA university, Seoul, Republic of Korea

Locations

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National Health Insurance Service Ilsan Hospital

Goyang, , South Korea

Site Status

CHA Gangnam Medical Center

Seoul, , South Korea

Site Status

Kangbuk Samsung Hospital

Seoul, , South Korea

Site Status

Samsung Medical Center

Seoul, , South Korea

Site Status

Countries

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South Korea

References

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Song T, Kim TJ, Lee SH, Kim TH, Kim WY. Laparoendoscopic single-site myomectomy compared with conventional laparoscopic myomectomy: a multicenter, randomized, controlled trial. Fertil Steril. 2015 Nov;104(5):1325-31. doi: 10.1016/j.fertnstert.2015.07.1137. Epub 2015 Aug 8.

Reference Type DERIVED
PMID: 26263079 (View on PubMed)

Other Identifiers

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MYO04

Identifier Type: -

Identifier Source: org_study_id