Trial Outcomes & Findings for Asthma Express: Bridging the Emergency to Primary Care in Underserved Children (NCT NCT01981564)

NCT ID: NCT01981564

Last Updated: 2019-03-06

Results Overview

Symptom days for asthma during past 14 days

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

222 participants

Primary outcome timeframe

3 months

Results posted on

2019-03-06

Participant Flow

Participant milestones

Participant milestones
Measure
Asthma Express Intervention
Clinic visit for asthma education + nurse home visits Asthma Express Intervention: Asthma Express clinic visit for asthma education + nurse home visit Asthma Express Control Arm: Asthma Express home nurse visits for asthma education
Standard ASthma Education Control Group
STandard asthma education delivered in home by nurse Asthma Express Intervention: Asthma Express clinic visit for asthma education + nurse home visit Asthma Express Control Arm: Asthma Express home nurse visits for asthma education
Overall Study
STARTED
107
115
Overall Study
COMPLETED
98
106
Overall Study
NOT COMPLETED
9
9

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

3 caregivers did not report number of ED visits over past 3 months at the baseline survey.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Asthma Express Intervention
n=107 Participants
Clinic visit for asthma education + nurse home visits Asthma Express Intervention: Asthma Express clinic visit for asthma education + nurse home visit Asthma Express Control Arm: Asthma Express home nurse visits for asthma education
Standard ASthma Education Control Group
n=115 Participants
STandard asthma education delivered in home by nurse Asthma Express Intervention: Asthma Express clinic visit for asthma education + nurse home visit Asthma Express Control Arm: Asthma Express home nurse visits for asthma education
Total
n=222 Participants
Total of all reporting groups
Age, Categorical
<=18 years
107 Participants
n=107 Participants
115 Participants
n=115 Participants
222 Participants
n=222 Participants
Age, Categorical
Between 18 and 65 years
0 Participants
n=107 Participants
0 Participants
n=115 Participants
0 Participants
n=222 Participants
Age, Categorical
>=65 years
0 Participants
n=107 Participants
0 Participants
n=115 Participants
0 Participants
n=222 Participants
Age, Continuous
6.2 years
STANDARD_DEVIATION 2.7 • n=107 Participants
6.5 years
STANDARD_DEVIATION 2.6 • n=115 Participants
6.3 years
STANDARD_DEVIATION 2.7 • n=222 Participants
Sex: Female, Male
Female
45 Participants
n=107 Participants
35 Participants
n=115 Participants
80 Participants
n=222 Participants
Sex: Female, Male
Male
62 Participants
n=107 Participants
80 Participants
n=115 Participants
142 Participants
n=222 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
4 Participants
n=107 Participants
3 Participants
n=115 Participants
7 Participants
n=222 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
103 Participants
n=107 Participants
112 Participants
n=115 Participants
215 Participants
n=222 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=107 Participants
0 Participants
n=115 Participants
0 Participants
n=222 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=107 Participants
0 Participants
n=115 Participants
0 Participants
n=222 Participants
Race (NIH/OMB)
Asian
0 Participants
n=107 Participants
0 Participants
n=115 Participants
0 Participants
n=222 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=107 Participants
0 Participants
n=115 Participants
0 Participants
n=222 Participants
Race (NIH/OMB)
Black or African American
101 Participants
n=107 Participants
107 Participants
n=115 Participants
208 Participants
n=222 Participants
Race (NIH/OMB)
White
4 Participants
n=107 Participants
3 Participants
n=115 Participants
7 Participants
n=222 Participants
Race (NIH/OMB)
More than one race
2 Participants
n=107 Participants
5 Participants
n=115 Participants
7 Participants
n=222 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=107 Participants
0 Participants
n=115 Participants
0 Participants
n=222 Participants
Region of Enrollment
United States
107 participants
n=107 Participants
115 participants
n=115 Participants
222 participants
n=222 Participants
Symptoms days past 14 days
5.55 symptom days
STANDARD_DEVIATION 4.6 • n=107 Participants
6.17 symptom days
STANDARD_DEVIATION 4.9 • n=115 Participants
5.88 symptom days
STANDARD_DEVIATION 4.8 • n=222 Participants
Emergency Department visits over past 3 months
1.02 Number of ED visits over past 3 months
STANDARD_DEVIATION 1.1 • n=105 Participants • 3 caregivers did not report number of ED visits over past 3 months at the baseline survey.
1.48 Number of ED visits over past 3 months
STANDARD_DEVIATION 1.6 • n=114 Participants • 3 caregivers did not report number of ED visits over past 3 months at the baseline survey.
1.26 Number of ED visits over past 3 months
STANDARD_DEVIATION 1.4 • n=219 Participants • 3 caregivers did not report number of ED visits over past 3 months at the baseline survey.

PRIMARY outcome

Timeframe: 3 months

Symptom days for asthma during past 14 days

Outcome measures

Outcome measures
Measure
Asthma Express Intervention
n=98 Participants
Asthma Express clinic visit for asthma education + nurse home visit
Standard ASthma Education Control Group
n=106 Participants
Asthma Express home nurse visits for asthma education
Symptom Days
6.24 symptom days over past 14 days
Standard Deviation 5.7
4.82 symptom days over past 14 days
Standard Deviation 5.1

SECONDARY outcome

Timeframe: 3 months

Population: No data for one participant in the control group for this outcome

Number of emergency department visits for asthma in the past 3 months

Outcome measures

Outcome measures
Measure
Asthma Express Intervention
n=98 Participants
Asthma Express clinic visit for asthma education + nurse home visit
Standard ASthma Education Control Group
n=105 Participants
Asthma Express home nurse visits for asthma education
Emergency Department (ED) Visits for Asthma
0.64 visits
Standard Deviation 2.26
0.62 visits
Standard Deviation 1.02

Adverse Events

Asthma Express Intervention

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Standard ASthma Education Control Group

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Arlene Butz

Johns Hopkins University School of Medicine, Department of Pediatrics

Phone: 410-614-5963

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place