Voice Analysis Using the LPC (Linear Predictive Coding)Method for the Prediction of Aspiration
NCT ID: NCT01981239
Last Updated: 2014-12-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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WITHDRAWN
NA
INTERVENTIONAL
2013-11-30
2014-12-31
Brief Summary
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In order to predict the degree of an aspitation,video-fluoroscopic-swallowing study and fiberoptic-endoscopic swallowing evaluation have been developed, but those evaluations are invasive and allowed only in a limited condition.
In this study, as a precedent study for the non-linear analysis, voice analysis using LPC method will be evaluated. The superiority of LPC method will be compared with a spectral analysis using Jitter and Simmer as a positive control.
This clinical study will be performed prospective, positive-controlled, single-blind (i.e. assessor-blind),and single cohort clinical trial for efficacy
Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
DIAGNOSTIC
SINGLE
Study Groups
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LPC analysis group
Voice sampling is executed before and immediately after drinking of 20ml N/S and linear voice analyses using LPC method are performed to calculate LPC index, residual variance, coefficiency mean, coeffiency variance, and coeffiency skewness.
VFSS
VFSS was perfomred one day before or after the voice sampling in the same patients according to the guideline of modified Longeman's protocol.
spectral analysis group
Voice sampling is executed before and immediately after drinking of 20ml N/S and spectral voice analyses using Dr. Speech program are performed to calculate HNR (dB), RAP (%: Jitter), Mean and SD Fundamental Frequency (Hz: Fo), Shimmer (%) and SNR (dB).
VFSS
VFSS was perfomred one day before or after the voice sampling in the same patients according to the guideline of modified Longeman's protocol.
Interventions
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VFSS
VFSS was perfomred one day before or after the voice sampling in the same patients according to the guideline of modified Longeman's protocol.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Preexisting oro-laryngo-pharyngeal disease
* Patients cannot follow 1 step command
* Patients cannot maintain a phonation for 3 seconds
* Refusal of participation
* Patients who were not classified for the candidate by physicians
* Patients who coughs following drinking of 5ml normal saline
ALL
No
Sponsors
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Ulsan University Hospital
OTHER
Responsible Party
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Chang Ho Hwang
Associate Professor
Principal Investigators
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Chang Ho Hwang, M.D. & Ph.D.
Role: STUDY_DIRECTOR
Ulsan University Hospital
Hyungseob Han, M.Sc.
Role: PRINCIPAL_INVESTIGATOR
University of Ulsan
Locations
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Ulsan University Hospital
Ulsan, , South Korea
Countries
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Other Identifiers
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chhwang4
Identifier Type: -
Identifier Source: org_study_id