Probiotics and Recovery From Surgery

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

TERMINATED

Clinical Phase

PHASE3

Total Enrollment

140 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-08-31

Study Completion Date

2017-02-28

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The study will investigate whether probiotics given just before and shortly after major abdominal operation improve outcomes.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Probiotics and Recovery From Gastrointestinal Surgery - 2

NCT04266106

Surgical Recovery

UNKNOWN PHASE3

Effect of Probiotics Before Cesarean Section on Postoperative Recovery in Pregnant Women

NCT06347770

Microbiota Postoperative Recovery

RECRUITING NA

The Impact of Probiotics on Bariatric Treatment Outcomes

NCT07258732

Obesity &Amp; Overweight

ACTIVE_NOT_RECRUITING NA

Determination of the Safety and Efficacy of Two Probiotic Strains

NCT06466174

Gastrointestinal Dysfunction

NOT_YET_RECRUITING NA

Effect of Probiotics After Neurosurgery

NCT07200518

Healing

RECRUITING NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Perioperative probiotic intervention is associated with approximately 30% reduction of primary outcome measure.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Major Abdominal Operation

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

VSL #3

probiotics given orally BID

Group Type EXPERIMENTAL

VSL #3 BID

Intervention Type DIETARY_SUPPLEMENT

placebo

Near-identically appearing placebo

Group Type OTHER

VSL #3 BID

Intervention Type DIETARY_SUPPLEMENT

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

VSL #3 BID

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* All elective major GI surgical patients

Exclusion Criteria

* • Current episode of acute pancreatitis as defined by clinician

* Active medication-induced immunosuppression including systemic corticosteroids, chemotherapy within 4 weeks, immunomodulating agents with transplant indication, biologicals for rheumatoid arthritis and inflammatory bowel disease. Topical chemotherapy or corticosteroids, and chemotherapy applied during operation are allowed.

Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No