Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
PHASE4
14500 participants
INTERVENTIONAL
2013-09-30
2024-04-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
QUADRUPLE
Study Groups
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Aspirin
100 mg enteric-coated aspirin
Aspirin
100mg enteric-coated aspirin, taken daily
Placebo
Placebo
Placebo
100mg enteric-coated placebo, taken daily
Interventions
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Aspirin
100mg enteric-coated aspirin, taken daily
Placebo
100mg enteric-coated placebo, taken daily
Eligibility Criteria
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Exclusion Criteria
iii. Cardiovascular events, intercurrent illness likely to cause death within the next 5 years, a current or recurrent condition with a high risk of major bleeding, e.g. cerebral aneurysm, cerebral AV malformation, any bleeding diathesis, recent peptic ulcer and liver disease.
iv. Anemia, i.e. hemoglobin level below the normal value (males: 12 g/dL, females: 11 g/dL).
3. Participants eligible for the ASPREE Cancer Endpoints Study (ACES) include any participants recruited into the parent ASPREE study in the United States and Australia. ACES participants will be asked to consent to:
i. Collection and storage of blood or saliva DNA samples and urine and data for future use. If ASPREE participants are unwilling to contribute biological samples, this will not in any way jeopardize their continued enrolment in ASPREE.
ii. Collection of cancer tumor specimens and storage and data for future use.
65 Years
ALL
Yes
Sponsors
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National Cancer Institute (NCI)
NIH
National Institute on Aging (NIA)
NIH
Monash University
OTHER
Berman Center for Outcomes and Clinical Research
OTHER
National Health and Medical Research Council, Australia
OTHER
Bayer
INDUSTRY
Hennepin Healthcare Research Institute
OTHER
Responsible Party
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Principal Investigators
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Anne Murray, MD, MSc
Role: PRINCIPAL_INVESTIGATOR
Berman Center
Locations
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The University of Alabama at Birmingham
Birmingham, Alabama, United States
Palo Alto Medical Foundation Research Institute
Palo Alto, California, United States
Howard University
Washington D.C., District of Columbia, United States
University of Florida Department of Aging and Geriatrics
Gainesville, Florida, United States
Morehouse School of Medicine
Atlanta, Georgia, United States
Emory/ Atlanta VAMC
Atlanta, Georgia, United States
Georgia Health Sciences University
Augusta, Georgia, United States
Rush Alzheimer's Disease Center
Chicago, Illinois, United States
University of Iowa
Iowa City, Iowa, United States
Kansas University Medical Center
Kansas City, Kansas, United States
Baton Rouge General
Baton Rouge, Louisiana, United States
Pennington Biomedical Research Center
Baton Rouge, Louisiana, United States
Mary Bird Perkins Our Lady of the Lake Cancer Center
Baton Rouge, Louisiana, United States
Mary Bird Perkins St. Tammany Parish Hospital
Covington, Louisiana, United States
Mary Bird Perkins Terrebonne General Hospital
Houma, Louisiana, United States
LSU Health Sciences- New Orleans
New Orleans, Louisiana, United States
Tulane Medical Center
New Orleans, Louisiana, United States
LSU Health Sciences- Shreveport
Shreveport, Louisiana, United States
University of Michigan
Ann Arbor, Michigan, United States
Wayne State University
Detroit, Michigan, United States
Henry Ford Health System
Detroit, Michigan, United States
Detroit Clinical Research Center
Novi, Michigan, United States
HealthPartners Research Institute
Minneapolis, Minnesota, United States
Phalen Village Clinic
Saint Paul, Minnesota, United States
Central Jersey Medical Center
Elizabeth, New Jersey, United States
New Jersey Medical College
Newark, New Jersey, United States
SUNY Downstate Medical Center
Brooklyn, New York, United States
Winthrop University Hospital
Mineola, New York, United States
Queens Cancer Medical Center
Queens, New York, United States
Wake Forest University Baptist Medical Center
Greensboro, North Carolina, United States
The Brody School of Medicine at ECU
Greenville, North Carolina, United States
Albert Einstein Medical Center
Philadelphia, Pennsylvania, United States
University of Pittsburgh Health Sciences Research Center
Pittsburgh, Pennsylvania, United States
Memorial Hospital of Rhode Island
Pawtucket, Rhode Island, United States
University of Tennessee Health Science Center
Memphis, Tennessee, United States
Meharry Medical College
Nashville, Tennessee, United States
University of Texas Southwestern Medical Center at Dallas
Dallas, Texas, United States
University of TX Medical Branch
Galveston, Texas, United States
Regional Academic Health Center
Harlingen, Texas, United States
UT Health Science Center at San Antonio
San Antonio, Texas, United States
Countries
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Related Links
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Public ASPREE website
Other Identifiers
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