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Mean Systemic Pressure Measurement During Prone Position Surgery

NCT ID: NCT01957605

Last Updated: 2015-09-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-12-31

Study Completion Date

2016-10-31

Brief Summary

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Venous return is driven by the pressure gradient between mean systemic pressure and right atrial pressure. However, mean systemic pressure is more a physiological concept than an available clinical measurement. Indeed, the mean systemic pressure is the one that would be measured anywhere within the vascular system after cardiac arrest. Recent advances in hemodynamic monitoring have made MSP available to the clinician through beat-by-beat cardiac output measurements during respiratory pauses under mechanical ventilation. In this way, it is possible to calculate MSP, the pressure gradient and the venous return resistances. The investigators aim is to explain the hemodynamic variations and the decrease in cardiac output observed during prone position. The investigators hypothesis is that venous return resistances are increased during prone position probably following an increased intra-abdominal pressure.

Detailed Description

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Conditions

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Hemodynamic Variation During Surgery

Keywords

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prone position hemodynamic variation mean systemic pressure

Study Design

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Study Time Perspective

CROSS_SECTIONAL

Study Groups

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prone position

Patient scheduled for surgery in the prone position

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Prone position neurosurgery
* High-risk neurosurgery

Exclusion Criteria

* Emergency surgery
* Pregnancy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Strasbourg, France

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Julien Pottecher, MD

Role: PRINCIPAL_INVESTIGATOR

University Hospital of Strasbourg

Locations

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University Hospital of Strasbourg

Strasbourg, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Julien Pottecher, MD

Role: CONTACT

Phone: +33(0)3 88 12 70 95

Email: [email protected]

Other Identifiers

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5673

Identifier Type: -

Identifier Source: org_study_id