Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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TERMINATED
PHASE2/PHASE3
63 participants
INTERVENTIONAL
2013-12-31
2019-04-23
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Propranolol
Propranolol by mouth given daily throughout hospitalization for up to 12 months
Propranolol
Propranolol by mouth given daily throughout hospitalization for up to 12 months
Sugar Pill
Placebo by mouth given daily throughout hospitalization for up to 12 months
Placebo
Placebo by mouth given daily throughout hospitalization for up to 12 months.
Interventions
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Propranolol
Propranolol by mouth given daily throughout hospitalization for up to 12 months
Placebo
Placebo by mouth given daily throughout hospitalization for up to 12 months.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Age of 0 to 18 years
* Patient arrival to the burn center within 96 hours (4 days) of burn injury
* Require \> 1 surgical procedure
Exclusion Criteria
* Known history of AIDS, Aids Related Complex, or HIV
* History of cancer within 5 years
* Existence of pre-morbid conditions
* Asthma
* Congestive heart failure (measured ejection fraction \< 20%)
* Medical condition requiring glucocorticoid treatment
* Burn injury due to chemical burns
* Burn injury due to deep electrical injury (decision of hospital PI)
* Presence of anoxic brain injury that is not expected to result in complete recovery
* Decision not to treat due to burn injury severity
18 Years
ALL
No
Sponsors
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Shriners Hospitals for Children
OTHER
The University of Texas Medical Branch, Galveston
OTHER
Responsible Party
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Principal Investigators
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David N Herndon, MD
Role: PRINCIPAL_INVESTIGATOR
University of Texas
Locations
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Shriners Hospitals for Children
Sacramento, California, United States
Shriners Hospitals for Children
Boston, Massachusetts, United States
Shriners Hospitals for Children
Cincinnati, Ohio, United States
Shriners Hospitals for Children
Galveston, Texas, United States
Countries
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Other Identifiers
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13-103
Identifier Type: -
Identifier Source: org_study_id
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