Fall Risk Reduction in Multiple Sclerosis: Exercise Versus Behavior
NCT ID: NCT01956227
Last Updated: 2014-11-25
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE1/PHASE2
37 participants
INTERVENTIONAL
2013-04-30
2014-09-30
Brief Summary
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Detailed Description
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It is well known that causes of falls are multifactorial with over 400 risk factors identified. However, it is believed that these factors can be divided into two main classes: intrinsic (e.g. physiological factors) and extrinsic factors. For instance balance dysfunction, spasticity and muscle weakness are physiological risk factors for falls in MS . Behavioral fall risk factors in MS include choosing appropriate footwear, lighting and utilizing appropriate assistive device. There is evidence that both types of risk factors can be minimized with appropriately designed interventions in persons with MS and have been shown to reduce fall risk and incidence in other clinical populations. This has led to calls for the combination of exercise training program that targets specific, modifiable physiological risk factors and educational interventions targeting modifiable behavioral risk factors in persons with MS. However, there is minimal evidence that these interventions in isolation or combination actually reduce fall incidence or risk in persons with MS. This proposal seeks to determine the effectiveness of a combined exercise and educational rehabilitation strategy to prevent falls in persons with MS.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
SINGLE
Study Groups
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Home-based Exercise
Participants will be taught a series of exercises targeting balance and lower limb strength in four instructional sessions. They will be asked to complete exercises 3 times a week for 12 weeks. Exercise compliance will be recorded with a diary.
Home-based exercise
exercise to look at balance and lower limb strength record in diary
Education
Participants will attend 4 education sessions focusing on interaction of beliefs, behaviors and symptoms on falls. They will be taught self-management principles to modify their fall risk.
Education
sessions to discuss self-management ideas to modify risk of falling
Exercise plus education
Participants will attend 2 instructional exercise sessions as well as 2 education sessions. Participants will be asked to complete exercises at home 3 times per week and engage in behavior to minimize fall risk.
Exercise plus Education
combination of exercise sessions with education sessions to modify fall risk
Control
Participants will not receive any treatment.
No interventions assigned to this group
Interventions
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Home-based exercise
exercise to look at balance and lower limb strength record in diary
Education
sessions to discuss self-management ideas to modify risk of falling
Exercise plus Education
combination of exercise sessions with education sessions to modify fall risk
Eligibility Criteria
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Inclusion Criteria
* ambulatory
* aged 50-75 years of age
* fallen within 12 months
Exclusion Criteria
* outside age range
* no fall history
50 Years
75 Years
ALL
No
Sponsors
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University of Illinois at Urbana-Champaign
OTHER
Responsible Party
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Principal Investigators
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Jacob Sosnoff
Role: PRINCIPAL_INVESTIGATOR
University of Illinois at Urbana-Champaign
Locations
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University of Illinois UC
Urbana, Illinois, United States
Countries
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References
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Sosnoff JJ, Moon Y, Wajda DA, Finlayson ML, McAuley E, Peterson EW, Morrison S, Motl RW. Fall risk and incidence reduction in high risk individuals with multiple sclerosis: a pilot randomized control trial. Clin Rehabil. 2015 Oct;29(10):952-60. doi: 10.1177/0269215514564899. Epub 2014 Dec 23.
Other Identifiers
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NMSS-IL-006
Identifier Type: -
Identifier Source: org_study_id