Measurement and Evaluation of Total Lung Capacity (TLC) in the Field of Pulmonary Functional Testing (PFT)

NCT ID: NCT01952431

Last Updated: 2014-11-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-04-30

Study Completion Date

2013-09-30

Brief Summary

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A comparative study to test the efficacy of a novel device - the MiniBoxPFT, in measuring TLC (total lung capacity) compared to TLC measured by standard body plethysmography using the ZAN 500. The study will be conducted as a prospective two-arm, open, randomized comparative study.

Detailed Description

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This study is a prospective, multi-centered, randomized, comparative study designed to demonstrate substantially equivalence performance of the proposed device, the PulmOne MiniBoxPFT, to its predicate device, the ZAN500, for the measurement of total lung capacity (TLC).

Conditions

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TLC in Patients With and Without Respiratory System Disease

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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PulmOne MiniBox PFT

Total Lung Capacity (TLC) testing with PulmOne MiniBoxPFT

Group Type EXPERIMENTAL

Total Lung Capacity (TLC) testing

Intervention Type DEVICE

Comparison of TLC results

ZAN500

Total Lung Capacity (TLC) testing with ZAN500.

Group Type ACTIVE_COMPARATOR

Total Lung Capacity (TLC) testing

Intervention Type DEVICE

Comparison of TLC results

Interventions

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Total Lung Capacity (TLC) testing

Comparison of TLC results

Intervention Type DEVICE

Other Intervention Names

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TLC

Eligibility Criteria

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Inclusion Criteria

1. Subject is at least 18 years of age.
2. Subject is cooperative and capable of following instructions.
3. Healthy subjects:

1. Never smokers.
2. No known history of respiratory, cardiovascular, hepatic, renal or metabolic disease.
3. BMI \< 35.
4. No persisting respiratory symptoms during the last 12 months. (e.g., dyspnea, chronic cough, wheezing or phlegm).
5. No history suggesting upper respiratory infection during the three weeks prior to testing.
4. Patients with known disease affecting the respiratory system, with previous documentation of obstructive, restrictive, or mixed obstructive plus restrictive ventilatory abnormality.

Exclusion Criteria

1. Subjects who are unable to satisfactorily perform routine, full lung function testing(due to non-compliance or claustrophobia).
2. Subjects unable or unwilling to give informed consent.
3. Subjects who have performed any significant physical activity during 1 hour prior to the Study.
4. Patients with a tracheostomy.
5. Pregnant women.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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PulmOne Advanced Medical Devices, Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Mordechai Yigla, MD

Role: PRINCIPAL_INVESTIGATOR

Rambam University Medical Center

Locations

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Rambam University Medical Center

Haifa, , Israel

Site Status

Countries

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Israel

Other Identifiers

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PulmOne-1.0

Identifier Type: -

Identifier Source: org_study_id