Evaluation of a New Daily Disposable Multifocal Contact Lens Design

NCT ID: NCT01951573

Last Updated: 2014-12-02

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

36 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-10-31

Study Completion Date

2013-11-30

Brief Summary

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The purpose of this study is to demonstrate non-inferiority of a new daily disposable multifocal contact lens in plus powers against the commercially available AIR OPTIX® AQUA MULTIFOCAL (AOAMF) lens in high contrast/high illumination (HC/HI) near visual acuity (VA).

Detailed Description

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Conditions

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Presbyopia Hyperopia Refractive Error

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Delefilcon A MF, then AOAMF

Delefilcon A multifocal contact lenses first, followed by lotrafilcon B multifocal contact lenses. Each product worn bilaterally (ie, in both eyes) for 9-12 hours, with a 1-8 day washout separating the 2 wear periods.

Group Type OTHER

Delefilcon A multifocal contact lenses

Intervention Type DEVICE

Silicone hydrogel multifocal contact lenses for daily wear, daily disposable use

Lotrafilcon B multifocal contact lenses

Intervention Type DEVICE

Silicone hydrogel multifocal contact lenses with a labeled indication for daily wear and extended wear use of up to 6 days with monthly replacement

AOAMF, then Delefilcon A MF

Lotrafilcon B multifocal contact lenses first, followed by delefilcon A multifocal contact lenses. Each product worn bilaterally (ie, in both eyes) for 9-12 hours, with a 1-8 day washout separating the 2 wear periods.

Group Type OTHER

Delefilcon A multifocal contact lenses

Intervention Type DEVICE

Silicone hydrogel multifocal contact lenses for daily wear, daily disposable use

Lotrafilcon B multifocal contact lenses

Intervention Type DEVICE

Silicone hydrogel multifocal contact lenses with a labeled indication for daily wear and extended wear use of up to 6 days with monthly replacement

Interventions

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Delefilcon A multifocal contact lenses

Silicone hydrogel multifocal contact lenses for daily wear, daily disposable use

Intervention Type DEVICE

Lotrafilcon B multifocal contact lenses

Silicone hydrogel multifocal contact lenses with a labeled indication for daily wear and extended wear use of up to 6 days with monthly replacement

Intervention Type DEVICE

Other Intervention Names

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AIR OPTIX® AQUA MULTIFOCAL

Eligibility Criteria

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Inclusion Criteria

* Subjects with normal eyes who are not using any ocular medication.
* Must sign the Informed Consent document.
* Habitual lens power within the range available for the study lenses (+1.00 to +3.50 diopters(D)).
* Manifest cylinder less than or equal to 0.75D.
* Best corrected distance VA greater than or equal to 20/25 in each eye.
* Existing soft contact lens (CL) wearers who wear contact lenses in both eyes at least 5 days per week.
* Presbyopic with a spectacle addition (ADD) \>0.50D and \<2.75D.

Exclusion Criteria

* Any ocular disease, inflammation, or abnormality that contraindicates CL wear.
* Any use of systemic or ocular medications for which CL wear could be contraindicated.
* History of herpetic keratitis.
* History of refractive surgery or irregular cornea.
* A clinically significant dry eye that precludes CL wear.
* Participation of the subject in a clinical study (including CL or CL care product) within the previous 30 days.
* Monocular (only 1 eye with functional vision).
* History of intolerance or hypersensitivity to any component of the test articles.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Alcon Research

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Joachim Nick, Dipl. Ing.

Role: STUDY_DIRECTOR

CIBA VISION GmbH

Other Identifiers

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C-13-011

Identifier Type: -

Identifier Source: org_study_id