Trial Outcomes & Findings for Hepatic Artery Infusion With FOLFOX in Liver Metastasis From Breast Cancer (NCT NCT01937507)

NCT ID: NCT01937507

Last Updated: 2018-02-07

Results Overview

To determine response rate (RR) of HAI with oxaliplatin/5-FU every three weeks in heavily pre-treated patients with advanced breast cancer with metastasis to the liver.

Recruitment status

TERMINATED

Study phase

PHASE2

Target enrollment

2 participants

Primary outcome timeframe

One year

Results posted on

2018-02-07

Participant Flow

Participant milestones

Participant milestones
Measure
HAI With FOLFOX
Hepatic Artery Infusion with Oxaliplatin, 5FU, and Folinic Acid HAI with FOLFOX: HAI with FOLFOX q 3 weeks
Overall Study
STARTED
2
Overall Study
COMPLETED
0
Overall Study
NOT COMPLETED
2

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Hepatic Artery Infusion With FOLFOX in Liver Metastasis From Breast Cancer

Baseline characteristics by cohort

Baseline data not reported

PRIMARY outcome

Timeframe: One year

Population: Data was not collected

To determine response rate (RR) of HAI with oxaliplatin/5-FU every three weeks in heavily pre-treated patients with advanced breast cancer with metastasis to the liver.

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: One year

Population: Data was not collected

To determine time to intra-hepatic progression (TIP) of HAI with oxaliplatin/5-FU every three weeks in heavily pre-treated patients with advanced breast cancer with metastasis to the liver.

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: One year

Population: Data was not collected

To determine time to extra-hepatic progression (TEP) of HAI with oxaliplatin/5-FU every three weeks in heavily pre-treated patients with advanced breast cancer with metastasis to the liver.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: one year

Population: Data was not collected

Document the toxicity and tolerability of the therapy using the following CBC with differential, BUN, creatinine, liver function tests,CA 15-3, CA 27.29, Circulating tumor cells (CTCs)and Restaging radiographic studies (MRI or CT liver protocol).

Outcome measures

Outcome data not reported

Adverse Events

HAI With FOLFOX

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Jessica L. Coats

CTCA

Phone: 6232073899

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place