Trial Outcomes & Findings for Saphenous Vein Cannulation in Infants and Small Children (NCT NCT01924975)

NCT ID: NCT01924975

Last Updated: 2018-01-23

Results Overview

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

102 participants

Primary outcome timeframe

10 minutes

Results posted on

2018-01-23

Participant Flow

Participant milestones

Participant milestones
Measure
Landmark Group
An operator is not allowed to use an ultrasound. A 22 or 24 G catheter will be advanced blindly toward the expected location of the saphenous vein at the level of the medial malleolus. Once blood appears in the hub, then the catheter will be advanced into the saphenous vein. Saphenous vein cannulation: Intravenous cannulation to saphenous vein A 22 or 24 G intravenous catheter
Ultrasound Group
An operator will identify the saphenous vein by using ultrasound with a linear transducer (L15-7io) in short axis view. A 22 or 24 G catheter will be advanced until the tip of the needle is seen on the ultrasound image. The needle is then advanced until blood appears in the hub. The catheter is then advanced into the saphenous vein. Saphenous vein cannulation: Intravenous cannulation to saphenous vein ultrasound with a linear transducer (L15-7io): Portable, bed-side ultrasound to detect saphenous vein A 22 or 24 G intravenous catheter
Overall Study
STARTED
51
51
Overall Study
COMPLETED
51
51
Overall Study
NOT COMPLETED
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Saphenous Vein Cannulation in Infants and Small Children

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Landmark Group
n=51 Participants
An operator is not allowed to use an ultrasound. A 22 or 24 G catheter will be advanced blindly toward the expected location of the saphenous vein at the level of the medial malleolus. Once blood appears in the hub, then the catheter will be advanced into the saphenous vein. Saphenous vein cannulation: Intravenous cannulation to saphenous vein A 22 or 24 G intravenous catheter
Ultrasound Group
n=51 Participants
An operator will identify the saphenous vein by using ultrasound with a linear transducer (L15-7io) in short axis view. A 22 or 24 G catheter will be advanced until the tip of the needle is seen on the ultrasound image. The needle is then advanced until blood appears in the hub. The catheter is then advanced into the saphenous vein. Saphenous vein cannulation: Intravenous cannulation to saphenous vein ultrasound with a linear transducer (L15-7io): Portable, bed-side ultrasound to detect saphenous vein A 22 or 24 G intravenous catheter
Total
n=102 Participants
Total of all reporting groups
Age, Continuous
12 months
n=5 Participants
8 months
n=7 Participants
11 months
n=5 Participants
Sex: Female, Male
Female
24 Participants
n=5 Participants
16 Participants
n=7 Participants
40 Participants
n=5 Participants
Sex: Female, Male
Male
27 Participants
n=5 Participants
35 Participants
n=7 Participants
62 Participants
n=5 Participants

PRIMARY outcome

Timeframe: 10 minutes

Outcome measures

Outcome measures
Measure
Landmark Group
n=51 Participants
An operator is not allowed to use an ultrasound. A 22 or 24 G catheter will be advanced blindly toward the expected location of the saphenous vein at the level of the medial malleolus. Once blood appears in the hub, then the catheter will be advanced into the saphenous vein. Saphenous vein cannulation: Intravenous cannulation to saphenous vein A 22 or 24 G intravenous catheter
Ultrasound Group
n=51 Participants
An operator will identify the saphenous vein by using ultrasound with a linear transducer (L15-7io) in short axis view. A 22 or 24 G catheter will be advanced until the tip of the needle is seen on the ultrasound image. The needle is then advanced until blood appears in the hub. The catheter is then advanced into the saphenous vein. Saphenous vein cannulation: Intravenous cannulation to saphenous vein ultrasound with a linear transducer (L15-7io): Portable, bed-side ultrasound to detect saphenous vein A 22 or 24 G intravenous catheter
Percentage of Participants With First Attempt Success of Saphenous Vein Cannulation
51.0 percent of participants
90.2 percent of participants

SECONDARY outcome

Timeframe: 10 minutes

Outcome measures

Outcome measures
Measure
Landmark Group
n=51 Participants
An operator is not allowed to use an ultrasound. A 22 or 24 G catheter will be advanced blindly toward the expected location of the saphenous vein at the level of the medial malleolus. Once blood appears in the hub, then the catheter will be advanced into the saphenous vein. Saphenous vein cannulation: Intravenous cannulation to saphenous vein A 22 or 24 G intravenous catheter
Ultrasound Group
n=51 Participants
An operator will identify the saphenous vein by using ultrasound with a linear transducer (L15-7io) in short axis view. A 22 or 24 G catheter will be advanced until the tip of the needle is seen on the ultrasound image. The needle is then advanced until blood appears in the hub. The catheter is then advanced into the saphenous vein. Saphenous vein cannulation: Intravenous cannulation to saphenous vein ultrasound with a linear transducer (L15-7io): Portable, bed-side ultrasound to detect saphenous vein A 22 or 24 G intravenous catheter
Percentage of Participants With Success of Saphenous Vein Cannulation Within 3 Attempts of Needle Insertion, or a 10 Minute Time Period.
62.8 percent of participants
92.2 percent of participants

SECONDARY outcome

Timeframe: 10 minutes

Population: Includes only those participants for which successful cannulation was achieved.

Outcome measures

Outcome measures
Measure
Landmark Group
n=32 Participants
An operator is not allowed to use an ultrasound. A 22 or 24 G catheter will be advanced blindly toward the expected location of the saphenous vein at the level of the medial malleolus. Once blood appears in the hub, then the catheter will be advanced into the saphenous vein. Saphenous vein cannulation: Intravenous cannulation to saphenous vein A 22 or 24 G intravenous catheter
Ultrasound Group
n=47 Participants
An operator will identify the saphenous vein by using ultrasound with a linear transducer (L15-7io) in short axis view. A 22 or 24 G catheter will be advanced until the tip of the needle is seen on the ultrasound image. The needle is then advanced until blood appears in the hub. The catheter is then advanced into the saphenous vein. Saphenous vein cannulation: Intravenous cannulation to saphenous vein ultrasound with a linear transducer (L15-7io): Portable, bed-side ultrasound to detect saphenous vein A 22 or 24 G intravenous catheter
Time Required for Overall Successful Venous Cannulation.
235 Seconds
Interval 179.0 to 300.0
151 Seconds
Interval 112.0 to 246.0

Adverse Events

Landmark Group

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Ultrasound Group

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Satoshi Hanada/Clinical Assistant Professor

University of Iowa Hopspital & Clinics

Phone: 3193561219

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place