Human Skin Test Model in Colostomists

NCT ID: NCT01918085

Last Updated: 2014-03-12

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

22 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-04-30

Study Completion Date

2012-05-31

Brief Summary

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The aim of the study is to investigate the correlation in peel force when peeling off a standard hydrocolloid adhesive strip and standard strata adhesive strip from peristomal skin compared to pre-stripped healthy abdominal skin in colostomists.

Detailed Description

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Conditions

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Colostomy Stoma

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Blinding Strategy

NONE

Study Groups

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Peristomal skin

The peel force used to remove two types of adhesive strips (Hydrocolloid strip and strata strip) from the Peristomal skin

Group Type OTHER

Hydrocolloid strip

Intervention Type OTHER

An adhesive strip made of hydrocolloid adhesive

Strata strip

Intervention Type OTHER

An adhesive strip made of the Strata adhesive

Pre-stripped abdominal skin

The peel force used to remove two types of adhesive strips (Hydrocolloid strip and strata strip) from healthy abdominal skin

Group Type OTHER

Hydrocolloid strip

Intervention Type OTHER

An adhesive strip made of hydrocolloid adhesive

Strata strip

Intervention Type OTHER

An adhesive strip made of the Strata adhesive

Interventions

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Hydrocolloid strip

An adhesive strip made of hydrocolloid adhesive

Intervention Type OTHER

Strata strip

An adhesive strip made of the Strata adhesive

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Have given written informed consent.
2. Be in the age of 45 to 75 years of age both extremes included.
3. Have had a colostomy for at least 1 year.
4. Has a colostomy with a diameter up to (≤) 40 mm.
5. Have mental capacity to understand the study guidelines and questionnaires.
6. Be assessed by the investigator as having a peristomal and abdominal skin condition justifying entry into the investigation.
7. Are colostomists currently using a 1-piece and 2-piece flat ostomy appliance.
8. Have a BMI between 20-30 kg/m2.
9. Are willing to comply with investigation procedures.

Exclusion Criteria

1. Currently suffering from peristomal skin problems (i.e. bleeding or broken skin).
2. Received radio- and/or chemotherapy within the last two months.
3. Currently using or have within the last 3 weeks used topical steroid products or other skin prep products.

on peristomal skin (injections and oral treatment are accepted).
4. Have dermatological problems.
5. Participating in other clinical studies or have previously participated in this test.
6. Be a daily user of a convex base-plate.
7. Are pregnant or breastfeeding.
8. Systemic elements that could affect skin histology (e.g. liver, kidney or immunological diseases).
Minimum Eligible Age

45 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Coloplast A/S

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Tonny Karlsmark, MD

Role: PRINCIPAL_INVESTIGATOR

Bispebjerg Hospital, Denmark

Other Identifiers

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CP228

Identifier Type: -

Identifier Source: org_study_id

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