Trial Outcomes & Findings for mActive: A Blinded, Randomized mHealth Activity Trial (NCT NCT01917812)

NCT ID: NCT01917812

Last Updated: 2017-03-23

Results Overview

Note that the study occurred over two study phases after the 1-week blinded run-in. In the first 2-week phase, participants were randomized to unblinded or blinded tracking. In the second 2-week phase, the unblinded participants were randomized to receive smart texts or no texts.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

48 participants

Primary outcome timeframe

Change from baseline mean daily step count at 3 weeks (end of unblinded digital activity tracker intervention)

Results posted on

2017-03-23

Participant Flow

We enrolled outpatients at an academic cardiovascular prevention center (Johns Hopkins Ciccarone Center) in Baltimore, Maryland, USA from January 17 to May 20, 2014.

Participant milestones

Participant milestones
Measure
Unblinded Digital Activity Tracker / Smart Text Messaging
Unblinded Digital Activity Tracker = Group unblinded to the numeric physical activity feedback information provided by the digital activity tracker. Smart Text Messaging = Group receives personalized, health coaching via "smart" text messages. Unblinded Digital Activity Tracker Smart Text Messaging
Blinded Digital Activity Tracker
Blinded Digital Activity Tracker = Group wears the tracker but is blinded to the numeric physical activity feedback information provided by the tracker. Blinded Digital Activity Tracker
Unblinded Digital Activity Tracker / No Smart Text Messaging
Unblinded Digital Activity Tracker = Group unblinded to the numeric physical activity feedback information provided by the digital activity tracker. No Smart Text Messaging = Group does not receive personalized, health coaching via "smart" text messages. Unblinded Digital Activity Tracker
Overall Study
STARTED
16
16
16
Overall Study
COMPLETED
16
15
16
Overall Study
NOT COMPLETED
0
1
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

mActive: A Blinded, Randomized mHealth Activity Trial

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Blinded Digital Activity Tracker
n=16 Participants
Blinded Digital Activity Tracker = Group wears the tracker but is blinded to the numeric physical activity feedback information provided by the tracker. Blinded Digital Activity Tracker
Unblinded Digital Activity Tracker / No Smart Text Messaging
n=16 Participants
Unblinded Digital Activity Tracker = Group unblinded to the numeric physical activity feedback information provided by the digital activity tracker. Unblinded Digital Activity Tracker
Unblinded Digital Activity Tracker / Smart Text Messaging
n=16 Participants
Unblinded Digital Activity Tracker = Group unblinded to the numeric physical activity feedback information provided by the digital activity tracker. Smart Text Messaging = Group receives personalized, health coaching via "smart" text messages. Unblinded Digital Activity Tracker Smart Text Messaging
Total
n=48 Participants
Total of all reporting groups
Age, Continuous
60 years
STANDARD_DEVIATION 7 • n=5 Participants
58 years
STANDARD_DEVIATION 8 • n=7 Participants
55 years
STANDARD_DEVIATION 8 • n=5 Participants
58 years
STANDARD_DEVIATION 8 • n=4 Participants
Sex: Female, Male
Female
7 Participants
n=5 Participants
7 Participants
n=7 Participants
8 Participants
n=5 Participants
22 Participants
n=4 Participants
Sex: Female, Male
Male
9 Participants
n=5 Participants
9 Participants
n=7 Participants
8 Participants
n=5 Participants
26 Participants
n=4 Participants
Region of Enrollment
United States
16 participants
n=5 Participants
16 participants
n=7 Participants
16 participants
n=5 Participants
48 participants
n=4 Participants

PRIMARY outcome

Timeframe: Change from baseline mean daily step count at 3 weeks (end of unblinded digital activity tracker intervention)

Note that the study occurred over two study phases after the 1-week blinded run-in. In the first 2-week phase, participants were randomized to unblinded or blinded tracking. In the second 2-week phase, the unblinded participants were randomized to receive smart texts or no texts.

Outcome measures

Outcome measures
Measure
Blinded Digital Activity Tracker
n=16 Participants
Unblinded Digital Activity Tracker
n=32 Participants
Unblinded Digital Activity Tracker / Smart Text Messaging
Mean Daily Step Count
-616 steps per day
Standard Deviation 2385
408 steps per day
Standard Deviation 2701

PRIMARY outcome

Timeframe: Change from 3 weeks mean daily step count at 5 weeks (end of smart text messaging intervention)

Note that the study occurred over two study phases after the 1-week blinded run-in. In the first 2-week phase, participants were randomized to unblinded or blinded tracking. In the second 2-week phase, the unblinded participants were randomized to receive smart texts or no texts.

Outcome measures

Outcome measures
Measure
Blinded Digital Activity Tracker
n=16 Participants
Unblinded Digital Activity Tracker
n=16 Participants
Unblinded Digital Activity Tracker / Smart Text Messaging
n=16 Participants
Mean Daily Step Count
-1042 steps per day
Standard Deviation 2202
-200 steps per day
Standard Deviation 1653
2334 steps per day
Standard Deviation 1714

SECONDARY outcome

Timeframe: Change from baseline mean daily activity time at 3 weeks (end of unblinded digital activity tracker intervention)

Note that the study occurred over two study phases after the 1-week blinded run-in. In the first 2-week phase, participants were randomized to unblinded or blinded tracking. In the second 2-week phase, the unblinded participants were randomized to receive smart texts or no texts.

Outcome measures

Outcome measures
Measure
Blinded Digital Activity Tracker
n=16 Participants
Unblinded Digital Activity Tracker
n=32 Participants
Unblinded Digital Activity Tracker / Smart Text Messaging
Mean Daily Activity Time
-6 minutes per day
Standard Deviation 26
2 minutes per day
Standard Deviation 27

SECONDARY outcome

Timeframe: Change from baseline mean daily aerobic activity time at 3 weeks (end of unblinded digital activity tracker intervention)

Defined as the time spent walking continuously for \>10 minutes without breaking for more than a minute. Note that the study occurred over two study phases after the 1-week blinded run-in. In the first 2-week phase, participants were randomized to unblinded or blinded tracking. In the second 2-week phase, the unblinded participants were randomized to receive smart texts or no texts.

Outcome measures

Outcome measures
Measure
Blinded Digital Activity Tracker
n=16 Participants
Unblinded Digital Activity Tracker
n=32 Participants
Unblinded Digital Activity Tracker / Smart Text Messaging
Mean Daily Aerobic Activity Time
-11 minutes per day
Standard Deviation 14
-3 minutes per day
Standard Deviation 12

SECONDARY outcome

Timeframe: Change from 3 weeks mean daily activity time at 5 weeks (end of smart text messaging intervention)

Note that the study occurred over two study phases after the 1-week blinded run-in. In the first 2-week phase, participants were randomized to unblinded or blinded tracking. In the second 2-week phase, the unblinded participants were randomized to receive smart texts or no texts.

Outcome measures

Outcome measures
Measure
Blinded Digital Activity Tracker
n=16 Participants
Unblinded Digital Activity Tracker
n=16 Participants
Unblinded Digital Activity Tracker / Smart Text Messaging
n=16 Participants
Mean Daily Activity Time
-8 minutes per day
Standard Deviation 23
0 minutes per day
Standard Deviation 17
21 minutes per day
Standard Deviation 20

SECONDARY outcome

Timeframe: Change from 3 weeks mean daily aerobic activity time at 5 weeks (end of smart text messaging intervention)

Note that the study occurred over two study phases after the 1-week blinded run-in. In the first 2-week phase, participants were randomized to unblinded or blinded tracking. In the second 2-week phase, the unblinded participants were randomized to receive smart texts or no texts.

Outcome measures

Outcome measures
Measure
Blinded Digital Activity Tracker
n=16 Participants
Unblinded Digital Activity Tracker
n=16 Participants
Unblinded Digital Activity Tracker / Smart Text Messaging
n=16 Participants
Mean Daily Aerobic Activity Time
-3 minutes per day
Standard Deviation 10
-1 minutes per day
Standard Deviation 8
13 minutes per day
Standard Deviation 11

Adverse Events

Blinded Digital Activity Tracker

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Unblinded Digital Activity Tracker / No Smart Text Messaging

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Unblinded Digital Activity Tracker / Smart Text Messaging

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Seth S Martin

Johns Hopkins University School of Medicine

Phone: 410-955-7376

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place